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2PI4

T7RNAP complexed with a phi10 protein and initiating GTPs.

Functional Information from GO Data
ChainGOidnamespacecontents
A0000428cellular_componentDNA-directed RNA polymerase complex
A0003677molecular_functionDNA binding
A0003899molecular_functionDNA-directed 5'-3' RNA polymerase activity
A0006351biological_processDNA-templated transcription
A0016779molecular_functionnucleotidyltransferase activity
A0019083biological_processviral transcription
A0034062molecular_function5'-3' RNA polymerase activity
A0039695biological_processDNA-templated viral transcription
Functional Information from PDB Data
site_idAC1
Number of Residues1
DetailsBINDING SITE FOR RESIDUE MG A 884
ChainResidue
AGH3901

site_idAC2
Number of Residues3
DetailsBINDING SITE FOR RESIDUE MG A 885
ChainResidue
AASP537
AASP812
AGH3902

site_idAC3
Number of Residues7
DetailsBINDING SITE FOR RESIDUE GH3 A 901
ChainResidue
AGH3902
TDC5
AARG394
AARG425
AASN437
AILE810
AMG884

site_idAC4
Number of Residues9
DetailsBINDING SITE FOR RESIDUE GH3 A 902
ChainResidue
ATYR571
AARG627
ATYR639
AHIS784
AASP812
AMG885
AGH3901
TDC4
TDC5

Functional Information from PROSITE/UniProt
site_idPS00489
Number of Residues15
DetailsRNA_POL_PHAGE_2 Bacteriophage-type RNA polymerase family active site signature 2. VtRsvtKrsVMTlaY
ChainResidueDetails
AVAL625-TYR639

site_idPS00900
Number of Residues12
DetailsRNA_POL_PHAGE_1 Bacteriophage-type RNA polymerase family active site signature 1. PLafDGSCSGIQ
ChainResidueDetails
APRO533-GLN544

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues2
DetailsACT_SITE: ACT_SITE => ECO:0000269|PubMed:8133519
ChainResidueDetails
AASP537
AASP812

site_idSWS_FT_FI2
Number of Residues1
DetailsACT_SITE: ACT_SITE => ECO:0000269|PubMed:1847871, ECO:0000269|PubMed:8133519
ChainResidueDetails
ALYS631

Catalytic Information from CSA
site_idCSA1
Number of Residues1
DetailsAnnotated By Reference To The Literature 1s76
ChainResidueDetails
ALYS631

226707

PDB entries from 2024-10-30

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