2PAH
TETRAMERIC HUMAN PHENYLALANINE HYDROXYLASE
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004497 | molecular_function | monooxygenase activity |
| A | 0004505 | molecular_function | phenylalanine 4-monooxygenase activity |
| A | 0005506 | molecular_function | iron ion binding |
| A | 0006559 | biological_process | L-phenylalanine catabolic process |
| A | 0009072 | biological_process | aromatic amino acid metabolic process |
| A | 0016714 | molecular_function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen |
| B | 0004497 | molecular_function | monooxygenase activity |
| B | 0004505 | molecular_function | phenylalanine 4-monooxygenase activity |
| B | 0005506 | molecular_function | iron ion binding |
| B | 0006559 | biological_process | L-phenylalanine catabolic process |
| B | 0009072 | biological_process | aromatic amino acid metabolic process |
| B | 0016714 | molecular_function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE FE A 453 |
| Chain | Residue |
| A | HIS285 |
| A | HIS290 |
| A | GLU330 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE FE B 454 |
| Chain | Residue |
| B | HIS285 |
| B | HIS290 |
| B | GLU330 |
| site_id | FE1 |
| Number of Residues | 3 |
| Details |
| Chain | Residue |
| A | HIS285 |
| A | HIS290 |
| A | GLU330 |
| site_id | FE2 |
| Number of Residues | 3 |
| Details |
| Chain | Residue |
| B | HIS285 |
| B | HIS290 |
| B | GLU330 |
Functional Information from PROSITE/UniProt
| site_id | PS00367 |
| Number of Residues | 12 |
| Details | BH4_AAA_HYDROXYL_1 Biopterin-dependent aromatic amino acid hydroxylases signature. PDicHELLGHVP |
| Chain | Residue | Details |
| A | PRO281-PRO292 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 6 |
| Details | Binding site: {"evidences":[{"source":"UniProtKB","id":"P04176","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
