2P7T

Crystal Structure of KcsA mutant

Functional Information from GO Data

Chain	GOid	namespace	contents
C	0005249	molecular_function	voltage-gated potassium channel activity
C	0006813	biological_process	potassium ion transport
C	0008076	cellular_component	voltage-gated potassium channel complex

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE K C 501

Chain	Residue
C	K502
C	K502
C	K502
C	K502

---

site_id	AC2
Number of Residues	8
Details	BINDING SITE FOR RESIDUE K C 502

Chain	Residue
C	HOH510
C	HOH510
C	HOH510
C	K501
C	K501
C	K501
C	K501
C	HOH510

---

site_id	AC3
Number of Residues	12
Details	BINDING SITE FOR RESIDUE K C 503

Chain	Residue
C	GLY77
C	GLY77
C	GLY77
C	GLY77
C	TYR78
C	TYR78
C	TYR78
C	TYR78
C	K504
C	K504
C	K504
C	K504

---

site_id	AC4
Number of Residues	16
Details	BINDING SITE FOR RESIDUE K C 504

Chain	Residue
C	VAL76
C	VAL76
C	VAL76
C	VAL76
C	GLY77
C	GLY77
C	GLY77
C	GLY77
C	K503
C	K503
C	K503
C	K503
C	K505
C	K505
C	K505
C	K505

---

site_id	AC5
Number of Residues	16
Details	BINDING SITE FOR RESIDUE K C 505

Chain	Residue
C	THR75
C	THR75
C	THR75
C	THR75
C	VAL76
C	VAL76
C	VAL76
C	VAL76
C	K504
C	K504
C	K504
C	K504
C	K506
C	K506
C	K506
C	K506

---

site_id	AC6
Number of Residues	8
Details	BINDING SITE FOR RESIDUE K C 506

Chain	Residue
C	THR75
C	THR75
C	THR75
C	THR75
C	K505
C	K505
C	K505
C	K505

---

site_id	AC7
Number of Residues	11
Details	BINDING SITE FOR RESIDUE 1EM C 507

Chain	Residue
C	LEU41
C	ALA42
C	SER44
C	TYR45
C	PRO63
C	TRP67
C	VAL84
C	LEU86
C	ARG89
C	HOH519
C	HOH541

---

site_id	AC8
Number of Residues	3
Details	BINDING SITE FOR RESIDUE F09 A 2001

Chain	Residue
A	ARG57
C	LEU46
C	TRP87

---

Functional Information from PROSITE/UniProt

site_id	PS00290
Number of Residues	7
Details	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YTCEATH

Chain	Residue	Details
B	TYR192-HIS198

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	45
Details	Transmembrane: {"description":"Helical"}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	16
Details	Topological domain: {"description":"Extracellular"}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	10
Details	Intramembrane: {"description":"Helical; Pore-forming"}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	7
Details	Intramembrane: {"description":"Pore-forming"}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	5
Details	Motif: {"description":"Selectivity filter"}

Chain

Residue

Details

---