2P6T

CRYSTAL STRUCTURE OF TRANSCRIPTIONAL REGULATOR NMB0573 and L-LEUCINE COMPLEX FROM NEISSERIA MENINGITIDIS

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0043565	molecular_function	sequence-specific DNA binding
B	0043565	molecular_function	sequence-specific DNA binding
C	0043565	molecular_function	sequence-specific DNA binding
D	0043565	molecular_function	sequence-specific DNA binding
E	0043565	molecular_function	sequence-specific DNA binding
F	0043565	molecular_function	sequence-specific DNA binding
G	0043565	molecular_function	sequence-specific DNA binding
H	0043565	molecular_function	sequence-specific DNA binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CA D 161

Chain	Residue
A	GLY67
D	ASN118

---

site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CA G 161

Chain	Residue
B	GLY67
B	HOH1162
B	HOH1163
G	ASN118

---

site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CA C 161

Chain	Residue
F	HOH1163
C	GLY67
C	HOH1161
F	ASN118

---

site_id	AC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CA E 161

Chain	Residue
E	GLY67
E	HOH1162
E	HOH1164

---

site_id	AC5
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA H 161

Chain	Residue
F	GLY104
F	GLU105
F	ASP107
F	LEU1160
H	ASP136
H	ALA137

---

site_id	AC6
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CA B 161

Chain	Residue
B	ASN118
G	GLY67

---

site_id	AC7
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CA E 162

Chain	Residue
E	ASP136
G	GLU105
G	ASP107

---

site_id	AC8
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CA H 162

Chain	Residue
H	GLU105

---

site_id	AC9
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CA B 162

Chain	Residue
B	GLY104
B	ASP107
B	LEU1160
D	ASP136
D	ALA137

---

site_id	BC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CA C 162

Chain	Residue
C	ASP136
E	GLU105

---

site_id	BC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CA H 163

Chain	Residue
E	HOH1179
H	GLY67
H	HOH1161
H	HOH1171
H	HOH1172

---

site_id	BC3
Number of Residues	11
Details	BINDING SITE FOR RESIDUE LEU A 1160

Chain	Residue
A	LEU102
A	THR103
A	GLY104
A	THR106
A	ASP107
A	HOH1165
G	LEU125
G	LEU129
G	ALA137
G	GLN138
G	SER139

---

site_id	BC4
Number of Residues	9
Details	BINDING SITE FOR RESIDUE LEU B 1160

Chain	Residue
B	LEU102
B	THR103
B	GLY104
B	ASP107
B	CA162
D	LEU129
D	ALA137
D	GLN138
D	SER139

---

site_id	BC5
Number of Residues	9
Details	BINDING SITE FOR RESIDUE LEU C 1160

Chain	Residue
A	LEU129
A	ALA137
A	GLN138
A	SER139
C	LEU102
C	THR103
C	GLY104
C	THR106
C	ASP107

---

site_id	BC6
Number of Residues	10
Details	BINDING SITE FOR RESIDUE LEU D 1160

Chain	Residue
C	LEU143
D	ARG83
D	LEU102
D	THR103
D	GLY104
D	ASP107
F	LEU129
F	ALA137
F	GLN138
F	SER139

---

site_id	BC7
Number of Residues	10
Details	BINDING SITE FOR RESIDUE LEU E 1160

Chain	Residue
C	LEU125
C	LEU129
C	ALA137
C	GLN138
C	SER139
E	LEU102
E	THR103
E	GLY104
E	THR106
E	ASP107

---

site_id	BC8
Number of Residues	12
Details	BINDING SITE FOR RESIDUE LEU F 1160

Chain	Residue
E	LEU143
F	ARG83
F	LEU102
F	THR103
F	GLY104
F	ASP107
H	VAL124
H	LEU125
H	ALA137
H	GLN138
H	SER139
H	CA161

---

site_id	BC9
Number of Residues	8
Details	BINDING SITE FOR RESIDUE LEU G 1160

Chain	Residue
E	ALA137
E	GLN138
E	SER139
G	LEU102
G	THR103
G	GLY104
H	LEU143
E	LEU129

---

site_id	CC1
Number of Residues	9
Details	BINDING SITE FOR RESIDUE LEU H 1160

Chain	Residue
B	ALA137
B	GLN138
B	SER139
H	ARG83
H	LEU102
H	THR103
H	GLY104
H	THR106
H	ASP107

---

site_id	CC2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE GOL D 901

Chain	Residue
A	ASN118
D	GLU62
D	GLY67

---

site_id	CC3
Number of Residues	2
Details	BINDING SITE FOR RESIDUE GOL E 907

Chain	Residue
E	ASN65
E	GOL809

---

site_id	CC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE GOL C 908

Chain	Residue
C	ASN118
F	GLU62
F	GLY67

---

site_id	CC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE GOL A 904

Chain	Residue
A	GLN15
A	VAL16
A	GLU19
A	ARG31

---

site_id	CC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE GOL D 803

Chain	Residue
D	ASN65
D	THR115
D	ASP116
D	HOH1169

---

site_id	CC7
Number of Residues	7
Details	BINDING SITE FOR RESIDUE GOL E 809

Chain	Residue
E	LEU68
E	ASP116
E	MSE117
E	GOL907
H	LEU68
H	ASP116
H	MSE117

---

Functional Information from PROSITE/UniProt

site_id	PS00519
Number of Residues	27
Details	HTH_ASNC_1 AsnC-type HTH domain signature. TnvELSerVALSpspclrRLkqLedaG

Chain	Residue	Details
A	THR24-GLY50

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