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2P5T

Molecular and structural characterization of the PezAT chromosomal toxin-antitoxin system of the human pathogen Streptococcus pneumoniae

Functional Information from GO Data
ChainGOidnamespacecontents
A0003677molecular_functionDNA binding
A0009636biological_processresponse to toxic substance
A0015643molecular_functiontoxic substance binding
A0031342biological_processnegative regulation of cell killing
B0005524molecular_functionATP binding
B0016301molecular_functionkinase activity
B0016310biological_processphosphorylation
C0003677molecular_functionDNA binding
C0009636biological_processresponse to toxic substance
C0015643molecular_functiontoxic substance binding
C0031342biological_processnegative regulation of cell killing
D0005524molecular_functionATP binding
D0016301molecular_functionkinase activity
D0016310biological_processphosphorylation
E0003677molecular_functionDNA binding
E0009636biological_processresponse to toxic substance
E0015643molecular_functiontoxic substance binding
E0031342biological_processnegative regulation of cell killing
F0005524molecular_functionATP binding
F0016301molecular_functionkinase activity
F0016310biological_processphosphorylation
G0003677molecular_functionDNA binding
G0009636biological_processresponse to toxic substance
G0015643molecular_functiontoxic substance binding
G0031342biological_processnegative regulation of cell killing
H0005524molecular_functionATP binding
H0016301molecular_functionkinase activity
H0016310biological_processphosphorylation
Functional Information from PROSITE/UniProt
site_idPS00675
Number of Residues14
DetailsSIGMA54_INTERACT_1 Sigma-54 interaction domain ATP-binding region A signature. ILLgGQSGAGKttI
ChainResidueDetails
BILE35-ILE48

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues4
DetailsACT_SITE: Proton acceptor => ECO:0000305
ChainResidueDetails
BASP66
DASP66
FASP66
HASP66

site_idSWS_FT_FI2
Number of Residues4
DetailsBINDING: BINDING => ECO:0000305|PubMed:17488720
ChainResidueDetails
BGLY39
DGLY39
FGLY39
HGLY39

226707

PDB entries from 2024-10-30

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