Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

2P3N

Thermotoga maritima IMPase TM1415

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0006020	biological_process	inositol metabolic process
A	0007165	biological_process	signal transduction
A	0008934	molecular_function	inositol monophosphate 1-phosphatase activity
A	0016787	molecular_function	hydrolase activity
A	0042132	molecular_function	fructose 1,6-bisphosphate 1-phosphatase activity
A	0046854	biological_process	phosphatidylinositol phosphate biosynthetic process
A	0046872	molecular_function	metal ion binding
A	0052832	molecular_function	inositol monophosphate 3-phosphatase activity
A	0052833	molecular_function	inositol monophosphate 4-phosphatase activity
A	0052834	molecular_function	inositol monophosphate phosphatase activity
B	0006020	biological_process	inositol metabolic process
B	0007165	biological_process	signal transduction
B	0008934	molecular_function	inositol monophosphate 1-phosphatase activity
B	0016787	molecular_function	hydrolase activity
B	0042132	molecular_function	fructose 1,6-bisphosphate 1-phosphatase activity
B	0046854	biological_process	phosphatidylinositol phosphate biosynthetic process
B	0046872	molecular_function	metal ion binding
B	0052832	molecular_function	inositol monophosphate 3-phosphatase activity
B	0052833	molecular_function	inositol monophosphate 4-phosphatase activity
B	0052834	molecular_function	inositol monophosphate phosphatase activity
C	0006020	biological_process	inositol metabolic process
C	0007165	biological_process	signal transduction
C	0008934	molecular_function	inositol monophosphate 1-phosphatase activity
C	0016787	molecular_function	hydrolase activity
C	0042132	molecular_function	fructose 1,6-bisphosphate 1-phosphatase activity
C	0046854	biological_process	phosphatidylinositol phosphate biosynthetic process
C	0046872	molecular_function	metal ion binding
C	0052832	molecular_function	inositol monophosphate 3-phosphatase activity
C	0052833	molecular_function	inositol monophosphate 4-phosphatase activity
C	0052834	molecular_function	inositol monophosphate phosphatase activity
D	0006020	biological_process	inositol metabolic process
D	0007165	biological_process	signal transduction
D	0008934	molecular_function	inositol monophosphate 1-phosphatase activity
D	0016787	molecular_function	hydrolase activity
D	0042132	molecular_function	fructose 1,6-bisphosphate 1-phosphatase activity
D	0046854	biological_process	phosphatidylinositol phosphate biosynthetic process
D	0046872	molecular_function	metal ion binding
D	0052832	molecular_function	inositol monophosphate 3-phosphatase activity
D	0052833	molecular_function	inositol monophosphate 4-phosphatase activity
D	0052834	molecular_function	inositol monophosphate phosphatase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	7
Details	BINDING SITE FOR RESIDUE MG A 1758

Chain	Residue
A	GLU65
A	ASP79
A	ILE81
A	ASP82
A	HOH2128
A	HOH2189
A	HOH2191

site_id	AC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG B 1759

Chain	Residue
B	ILE581
B	HOH2120
B	HOH2176
B	HOH2188
B	GLU565
B	ASP579

site_id	AC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG C 1761

Chain	Residue
C	GLU1065
C	ASP1079
C	ILE1081
C	HOH2105
C	HOH2107
C	HOH2193

site_id	AC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG D 1763

Chain	Residue
D	GLU1565
D	ASP1579
D	ILE1581
D	HOH2133
D	HOH2194
D	HOH2195

Functional Information from PROSITE/UniProt

site_id	PS00629
Number of Residues	14
Details	IMP_1 Inositol monophosphatase family signature 1. WiIDPIDGTinFvH

Chain	Residue	Details
A	TRP76-HIS89

site_id	PS00630
Number of Residues	15
Details	IMP_2 Inositol monophosphatase family signature 2. WDiAAGlIIVkeaGG

Chain	Residue	Details
A	TRP200-GLY214

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	8
Details	BINDING: BINDING => ECO:0000269\|PubMed:17419729

Chain	Residue	Details
A	GLU65
A	ILE81
B	GLU565
B	ILE581
C	GLU1065
C	ILE1081
D	GLU1565
D	ILE1581

site_id	SWS_FT_FI2
Number of Residues	24
Details	BINDING: BINDING => ECO:0000250

Chain	Residue	Details
A	ASP79
B	ALA677
B	ARG696
B	ASP701
C	ASP1079
C	ASP1082
C	ARG1172
C	ALA1177
C	ARG1196
C	ASP1201
D	ASP1579
A	ASP82
D	ASP1582
D	ARG1672
D	ALA1677
D	ARG1696
D	ASP1701
A	ARG172
A	ALA177
A	ARG196
A	ASP201
B	ASP579
B	ASP582
B	ARG672

Catalytic Information from CSA

site_id	CSA1
Number of Residues	2
Details	Annotated By Reference To The Literature 1ima

Chain	Residue	Details
A	THR84
A	GLU65

site_id	CSA2
Number of Residues	2
Details	Annotated By Reference To The Literature 1ima

Chain	Residue	Details
B	GLU565
B	THR584

site_id	CSA3
Number of Residues	2
Details	Annotated By Reference To The Literature 1ima

Chain	Residue	Details
C	THR1084
C	GLU1065

site_id	CSA4
Number of Residues	2
Details	Annotated By Reference To The Literature 1ima

Chain	Residue	Details
D	GLU1565
D	THR1584

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)