2OXQ

Structure of the UbcH5 :CHIP U-box complex

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0000209	biological_process	protein polyubiquitination
A	0005524	molecular_function	ATP binding
A	0005634	cellular_component	nucleus
A	0006511	biological_process	ubiquitin-dependent protein catabolic process
A	0016740	molecular_function	transferase activity
A	0031398	biological_process	positive regulation of protein ubiquitination
A	0061631	molecular_function	ubiquitin conjugating enzyme activity
A	0070936	biological_process	protein K48-linked ubiquitination
B	0000166	molecular_function	nucleotide binding
B	0000209	biological_process	protein polyubiquitination
B	0005524	molecular_function	ATP binding
B	0005634	cellular_component	nucleus
B	0006511	biological_process	ubiquitin-dependent protein catabolic process
B	0016740	molecular_function	transferase activity
B	0031398	biological_process	positive regulation of protein ubiquitination
B	0061631	molecular_function	ubiquitin conjugating enzyme activity
B	0070936	biological_process	protein K48-linked ubiquitination
C	0004842	molecular_function	ubiquitin-protein transferase activity
C	0016567	biological_process	protein ubiquitination
D	0004842	molecular_function	ubiquitin-protein transferase activity
D	0016567	biological_process	protein ubiquitination

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CL C 1

Chain	Residue
C	GLY214
C	LYS215
C	ILE216
C	SER217
C	ASP234

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site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CL D 6

Chain	Residue
C	ALA266
D	GLY230
D	ILE231
D	THR232

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site_id	AC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CL D 7

Chain	Residue
D	GLY214
D	LYS215
D	ILE216
D	SER217
D	ASP234
D	ASP237

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Functional Information from PROSITE/UniProt

site_id	PS00183
Number of Residues	16
Details	UBC_1 Ubiquitin-conjugating (UBC) active site signature. YHPNInsn.GsICLdiL

Chain	Residue	Details
A	TYR74-LEU89

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