Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

2OX8

Human Scavenger Receptor C-type Lectin carbohydrate-recognition domain.

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN A 1

Chain	Residue
A	CL6
A	CL7
A	HIS610
A	HIS641

site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE ZN A 2

Chain	Residue
A	CL8
A	TYR619
A	PHE644
A	GLU650
A	GLU731

site_id	AC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE ZN A 3

Chain	Residue
A	ASP616
A	LYS617
A	ASP733
A	HOH743
B	HIS700

site_id	AC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN A 4

Chain	Residue
A	ASP670
A	GLU674
A	HIS702
A	ASP707

site_id	AC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN A 5

Chain	Residue
A	GLU662
A	HIS664
A	HOH744
A	HOH746

site_id	AC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CL A 6

Chain	Residue
A	ZN1
A	HIS610
A	HIS641
A	ASP733

site_id	AC7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CL A 7

Chain	Residue
A	ZN1
A	HIS610
A	LYS617
A	GLU731

site_id	AC8
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CL A 8

Chain	Residue
A	ZN2
A	PHE644
A	ASN646
A	GLU650
A	GLU731

site_id	AC9
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN B 1

Chain	Residue
B	CL6
B	CL7
B	HIS610
B	HIS641

site_id	BC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN B 2

Chain	Residue
B	CL8
B	PHE644
B	GLU650
B	GLU731

site_id	BC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN B 3

Chain	Residue
A	HIS700
A	HOH745
B	ASP616
B	ASP733

site_id	BC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN B 4

Chain	Residue
B	ASP670
B	GLU674
B	HIS702
B	ASP707

site_id	BC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE ZN B 5

Chain	Residue
B	GLU662
B	HIS664
B	HOH743

site_id	BC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CL B 6

Chain	Residue
B	ZN1
B	HIS610
B	HIS641
B	ASP733

site_id	BC6
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CL B 7

Chain	Residue
B	ZN1
B	HIS610
B	LYS617
B	HIS641
B	GLU731

site_id	BC7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CL B 8

Chain	Residue
B	ZN2
B	PHE644
B	GLU650
B	GLU731

site_id	BC8
Number of Residues	8
Details	BINDING SITE FOR RESIDUE ZN C 1

Chain	Residue
C	CL3
C	CL4
C	HIS610
C	HIS641
D	TRP611
D	LYS612
D	TYR619
D	TYR620

site_id	BC9
Number of Residues	6
Details	BINDING SITE FOR RESIDUE ZN C 2

Chain	Residue
C	CL5
C	PHE644
C	GLU650
C	GLU731
D	PHE621
D	SER622

site_id	CC1
Number of Residues	8
Details	BINDING SITE FOR RESIDUE CL C 3

Chain	Residue
C	ZN1
C	HIS641
C	LYS732
C	ASP733
D	TRP611
D	LYS612
D	CYS618
D	TYR619

site_id	CC2
Number of Residues	7
Details	BINDING SITE FOR RESIDUE CL C 4

Chain	Residue
C	ZN1
C	HIS610
C	HIS641
C	GLU731
D	TYR619
D	TYR620
D	PHE621

site_id	CC3
Number of Residues	8
Details	BINDING SITE FOR RESIDUE CL C 5

Chain	Residue
C	GLU650
C	GLU731
D	TYR620
D	PHE621
D	SER622
C	ZN2
C	LYS617
C	PHE644

site_id	CC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CA C 6

Chain	Residue
C	ASP670
C	GLU674
C	ASN697
C	GLU706
C	ASP707

site_id	CC5
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CA C 7

Chain	Residue
C	GLN694
C	ASP696
C	GLU706
C	ASN718
C	ASP719

site_id	CC6
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CA C 8

Chain	Residue
C	GLU674
C	PRO704
C	ASP707

site_id	CC7
Number of Residues	3
Details	BINDING SITE FOR RESIDUE ZN C 9

Chain	Residue
B	ASP696
C	HOH32
C	HIS700

site_id	CC8
Number of Residues	8
Details	BINDING SITE FOR RESIDUE ZN D 1

Chain	Residue
C	TRP611
C	LYS612
C	TYR619
C	TYR620
D	CL3
D	CL4
D	HIS610
D	HIS641

site_id	CC9
Number of Residues	6
Details	BINDING SITE FOR RESIDUE ZN D 2

Chain	Residue
C	PHE621
C	SER622
D	CL5
D	PHE644
D	GLU650
D	GLU731

site_id	DC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CL D 3

Chain	Residue
C	TRP611
C	LYS612
C	CYS618
C	TYR619
D	ZN1
D	HIS641

site_id	DC2
Number of Residues	11
Details	BINDING SITE FOR RESIDUE CL D 4

Chain	Residue
C	HIS610
C	TRP611
C	LYS612
C	TYR619
C	TYR620
C	PHE621
D	ZN1
D	HIS610
D	LYS617
D	HIS641
D	GLU731

site_id	DC3
Number of Residues	7
Details	BINDING SITE FOR RESIDUE CL D 5

Chain	Residue
C	TYR620
C	PHE621
C	SER622
D	ZN2
D	PHE644
D	GLU650
D	GLU731

site_id	DC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CA D 6

Chain	Residue
D	ASP670
D	GLU674
D	ASN697
D	GLU706
D	ASP707

site_id	DC5
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CA D 7

Chain	Residue
D	GLN694
D	ASP696
D	GLU706
D	ASN718
D	ASP719

site_id	DC6
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CA D 8

Chain	Residue
D	GLU674
D	ASP707

site_id	DC7
Number of Residues	3
Details	BINDING SITE FOR RESIDUE ZN D 9

Chain	Residue
A	ASP696
D	HOH33
D	HIS700

Functional Information from PROSITE/UniProt

site_id	PS00615
Number of Residues	23
Details	C_TYPE_LECTIN_1 C-type lectin domain signature. CAgliyagq.....WNDFQCedvnn.FIC

Chain	Residue	Details
A	CYS708-CYS730

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	52
Details	BINDING:

Chain	Residue	Details
A	PHE644
A	ASP707
A	ASN718
A	ASP719
A	GLU731
B	PHE644
B	ASN646
B	GLU650
B	ASP670
B	GLU674
B	GLN694
A	ASN646
B	ASP696
B	ASN697
B	GLU706
B	ASP707
B	ASN718
B	ASP719
B	GLU731
C	PHE644
C	ASN646
C	GLU650
A	GLU650
C	ASP670
C	GLU674
C	GLN694
C	ASP696
C	ASN697
C	GLU706
C	ASP707
C	ASN718
C	ASP719
C	GLU731
A	ASP670
D	PHE644
D	ASN646
D	GLU650
D	ASP670
D	GLU674
D	GLN694
D	ASP696
D	ASN697
D	GLU706
D	ASP707
A	GLU674
D	ASN718
D	ASP719
D	GLU731
A	GLN694
A	ASP696
A	ASN697
A	GLU706

site_id	SWS_FT_FI2
Number of Residues	4
Details	BINDING: BINDING => ECO:0000250

Chain	Residue	Details
A	LYS691
B	LYS691
C	LYS691
D	LYS691

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)