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2OV2

The crystal structure of the human RAC3 in complex with the CRIB domain of human p21-activated kinase 4 (PAK4)

Functional Information from GO Data
ChainGOidnamespacecontents
A0003924molecular_functionGTPase activity
A0003925molecular_functionG protein activity
A0005515molecular_functionprotein binding
A0005525molecular_functionGTP binding
A0005737cellular_componentcytoplasm
A0005789cellular_componentendoplasmic reticulum membrane
A0005829cellular_componentcytosol
A0005856cellular_componentcytoskeleton
A0005886cellular_componentplasma membrane
A0007015biological_processactin filament organization
A0007163biological_processestablishment or maintenance of cell polarity
A0007264biological_processsmall GTPase-mediated signal transduction
A0008045biological_processmotor neuron axon guidance
A0008360biological_processregulation of cell shape
A0012505cellular_componentendomembrane system
A0014041biological_processregulation of neuron maturation
A0016055biological_processWnt signaling pathway
A0016601biological_processRac protein signal transduction
A0016787molecular_functionhydrolase activity
A0019901molecular_functionprotein kinase binding
A0021894biological_processcerebral cortex GABAergic interneuron development
A0022604biological_processregulation of cell morphogenesis
A0030027cellular_componentlamellipodium
A0030031biological_processcell projection assembly
A0030036biological_processactin cytoskeleton organization
A0030426cellular_componentgrowth cone
A0030865biological_processcortical cytoskeleton organization
A0031175biological_processneuron projection development
A0031410cellular_componentcytoplasmic vesicle
A0031941cellular_componentfilamentous actin
A0032956biological_processregulation of actin cytoskeleton organization
A0033630biological_processpositive regulation of cell adhesion mediated by integrin
A0035556biological_processintracellular signal transduction
A0042995cellular_componentcell projection
A0043005cellular_componentneuron projection
A0043020cellular_componentNADPH oxidase complex
A0043025cellular_componentneuronal cell body
A0043652biological_processengulfment of apoptotic cell
A0045730biological_processrespiratory burst
A0048306molecular_functioncalcium-dependent protein binding
A0048471cellular_componentperinuclear region of cytoplasm
A0048873biological_processhomeostasis of number of cells within a tissue
A0050885biological_processneuromuscular process controlling balance
A0050905biological_processneuromuscular process
A0051932biological_processsynaptic transmission, GABAergic
A0060326biological_processcell chemotaxis
A0070062cellular_componentextracellular exosome
A0071944cellular_componentcell periphery
A0098794cellular_componentpostsynapse
A0098974biological_processpostsynaptic actin cytoskeleton organization
A0098978cellular_componentglutamatergic synapse
A0150052biological_processregulation of postsynapse assembly
A1900026biological_processpositive regulation of substrate adhesion-dependent cell spreading
A1902622biological_processregulation of neutrophil migration
B0003924molecular_functionGTPase activity
B0003925molecular_functionG protein activity
B0005515molecular_functionprotein binding
B0005525molecular_functionGTP binding
B0005737cellular_componentcytoplasm
B0005789cellular_componentendoplasmic reticulum membrane
B0005829cellular_componentcytosol
B0005856cellular_componentcytoskeleton
B0005886cellular_componentplasma membrane
B0007015biological_processactin filament organization
B0007163biological_processestablishment or maintenance of cell polarity
B0007264biological_processsmall GTPase-mediated signal transduction
B0008045biological_processmotor neuron axon guidance
B0008360biological_processregulation of cell shape
B0012505cellular_componentendomembrane system
B0014041biological_processregulation of neuron maturation
B0016055biological_processWnt signaling pathway
B0016601biological_processRac protein signal transduction
B0016787molecular_functionhydrolase activity
B0019901molecular_functionprotein kinase binding
B0021894biological_processcerebral cortex GABAergic interneuron development
B0022604biological_processregulation of cell morphogenesis
B0030027cellular_componentlamellipodium
B0030031biological_processcell projection assembly
B0030036biological_processactin cytoskeleton organization
B0030426cellular_componentgrowth cone
B0030865biological_processcortical cytoskeleton organization
B0031175biological_processneuron projection development
B0031410cellular_componentcytoplasmic vesicle
B0031941cellular_componentfilamentous actin
B0032956biological_processregulation of actin cytoskeleton organization
B0033630biological_processpositive regulation of cell adhesion mediated by integrin
B0035556biological_processintracellular signal transduction
B0042995cellular_componentcell projection
B0043005cellular_componentneuron projection
B0043020cellular_componentNADPH oxidase complex
B0043025cellular_componentneuronal cell body
B0043652biological_processengulfment of apoptotic cell
B0045730biological_processrespiratory burst
B0048306molecular_functioncalcium-dependent protein binding
B0048471cellular_componentperinuclear region of cytoplasm
B0048873biological_processhomeostasis of number of cells within a tissue
B0050885biological_processneuromuscular process controlling balance
B0050905biological_processneuromuscular process
B0051932biological_processsynaptic transmission, GABAergic
B0060326biological_processcell chemotaxis
B0070062cellular_componentextracellular exosome
B0071944cellular_componentcell periphery
B0098794cellular_componentpostsynapse
B0098974biological_processpostsynaptic actin cytoskeleton organization
B0098978cellular_componentglutamatergic synapse
B0150052biological_processregulation of postsynapse assembly
B1900026biological_processpositive regulation of substrate adhesion-dependent cell spreading
B1902622biological_processregulation of neutrophil migration
C0003924molecular_functionGTPase activity
C0003925molecular_functionG protein activity
C0005515molecular_functionprotein binding
C0005525molecular_functionGTP binding
C0005737cellular_componentcytoplasm
C0005789cellular_componentendoplasmic reticulum membrane
C0005829cellular_componentcytosol
C0005856cellular_componentcytoskeleton
C0005886cellular_componentplasma membrane
C0007015biological_processactin filament organization
C0007163biological_processestablishment or maintenance of cell polarity
C0007264biological_processsmall GTPase-mediated signal transduction
C0008045biological_processmotor neuron axon guidance
C0008360biological_processregulation of cell shape
C0012505cellular_componentendomembrane system
C0014041biological_processregulation of neuron maturation
C0016055biological_processWnt signaling pathway
C0016601biological_processRac protein signal transduction
C0016787molecular_functionhydrolase activity
C0019901molecular_functionprotein kinase binding
C0021894biological_processcerebral cortex GABAergic interneuron development
C0022604biological_processregulation of cell morphogenesis
C0030027cellular_componentlamellipodium
C0030031biological_processcell projection assembly
C0030036biological_processactin cytoskeleton organization
C0030426cellular_componentgrowth cone
C0030865biological_processcortical cytoskeleton organization
C0031175biological_processneuron projection development
C0031410cellular_componentcytoplasmic vesicle
C0031941cellular_componentfilamentous actin
C0032956biological_processregulation of actin cytoskeleton organization
C0033630biological_processpositive regulation of cell adhesion mediated by integrin
C0035556biological_processintracellular signal transduction
C0042995cellular_componentcell projection
C0043005cellular_componentneuron projection
C0043020cellular_componentNADPH oxidase complex
C0043025cellular_componentneuronal cell body
C0043652biological_processengulfment of apoptotic cell
C0045730biological_processrespiratory burst
C0048306molecular_functioncalcium-dependent protein binding
C0048471cellular_componentperinuclear region of cytoplasm
C0048873biological_processhomeostasis of number of cells within a tissue
C0050885biological_processneuromuscular process controlling balance
C0050905biological_processneuromuscular process
C0051932biological_processsynaptic transmission, GABAergic
C0060326biological_processcell chemotaxis
C0070062cellular_componentextracellular exosome
C0071944cellular_componentcell periphery
C0098794cellular_componentpostsynapse
C0098974biological_processpostsynaptic actin cytoskeleton organization
C0098978cellular_componentglutamatergic synapse
C0150052biological_processregulation of postsynapse assembly
C1900026biological_processpositive regulation of substrate adhesion-dependent cell spreading
C1902622biological_processregulation of neutrophil migration
D0003924molecular_functionGTPase activity
D0003925molecular_functionG protein activity
D0005515molecular_functionprotein binding
D0005525molecular_functionGTP binding
D0005737cellular_componentcytoplasm
D0005789cellular_componentendoplasmic reticulum membrane
D0005829cellular_componentcytosol
D0005856cellular_componentcytoskeleton
D0005886cellular_componentplasma membrane
D0007015biological_processactin filament organization
D0007163biological_processestablishment or maintenance of cell polarity
D0007264biological_processsmall GTPase-mediated signal transduction
D0008045biological_processmotor neuron axon guidance
D0008360biological_processregulation of cell shape
D0012505cellular_componentendomembrane system
D0014041biological_processregulation of neuron maturation
D0016055biological_processWnt signaling pathway
D0016601biological_processRac protein signal transduction
D0016787molecular_functionhydrolase activity
D0019901molecular_functionprotein kinase binding
D0021894biological_processcerebral cortex GABAergic interneuron development
D0022604biological_processregulation of cell morphogenesis
D0030027cellular_componentlamellipodium
D0030031biological_processcell projection assembly
D0030036biological_processactin cytoskeleton organization
D0030426cellular_componentgrowth cone
D0030865biological_processcortical cytoskeleton organization
D0031175biological_processneuron projection development
D0031410cellular_componentcytoplasmic vesicle
D0031941cellular_componentfilamentous actin
D0032956biological_processregulation of actin cytoskeleton organization
D0033630biological_processpositive regulation of cell adhesion mediated by integrin
D0035556biological_processintracellular signal transduction
D0042995cellular_componentcell projection
D0043005cellular_componentneuron projection
D0043020cellular_componentNADPH oxidase complex
D0043025cellular_componentneuronal cell body
D0043652biological_processengulfment of apoptotic cell
D0045730biological_processrespiratory burst
D0048306molecular_functioncalcium-dependent protein binding
D0048471cellular_componentperinuclear region of cytoplasm
D0048873biological_processhomeostasis of number of cells within a tissue
D0050885biological_processneuromuscular process controlling balance
D0050905biological_processneuromuscular process
D0051932biological_processsynaptic transmission, GABAergic
D0060326biological_processcell chemotaxis
D0070062cellular_componentextracellular exosome
D0071944cellular_componentcell periphery
D0098794cellular_componentpostsynapse
D0098974biological_processpostsynaptic actin cytoskeleton organization
D0098978cellular_componentglutamatergic synapse
D0150052biological_processregulation of postsynapse assembly
D1900026biological_processpositive regulation of substrate adhesion-dependent cell spreading
D1902622biological_processregulation of neutrophil migration
E0003924molecular_functionGTPase activity
E0003925molecular_functionG protein activity
E0005515molecular_functionprotein binding
E0005525molecular_functionGTP binding
E0005737cellular_componentcytoplasm
E0005789cellular_componentendoplasmic reticulum membrane
E0005829cellular_componentcytosol
E0005856cellular_componentcytoskeleton
E0005886cellular_componentplasma membrane
E0007015biological_processactin filament organization
E0007163biological_processestablishment or maintenance of cell polarity
E0007264biological_processsmall GTPase-mediated signal transduction
E0008045biological_processmotor neuron axon guidance
E0008360biological_processregulation of cell shape
E0012505cellular_componentendomembrane system
E0014041biological_processregulation of neuron maturation
E0016055biological_processWnt signaling pathway
E0016601biological_processRac protein signal transduction
E0016787molecular_functionhydrolase activity
E0019901molecular_functionprotein kinase binding
E0021894biological_processcerebral cortex GABAergic interneuron development
E0022604biological_processregulation of cell morphogenesis
E0030027cellular_componentlamellipodium
E0030031biological_processcell projection assembly
E0030036biological_processactin cytoskeleton organization
E0030426cellular_componentgrowth cone
E0030865biological_processcortical cytoskeleton organization
E0031175biological_processneuron projection development
E0031410cellular_componentcytoplasmic vesicle
E0031941cellular_componentfilamentous actin
E0032956biological_processregulation of actin cytoskeleton organization
E0033630biological_processpositive regulation of cell adhesion mediated by integrin
E0035556biological_processintracellular signal transduction
E0042995cellular_componentcell projection
E0043005cellular_componentneuron projection
E0043020cellular_componentNADPH oxidase complex
E0043025cellular_componentneuronal cell body
E0043652biological_processengulfment of apoptotic cell
E0045730biological_processrespiratory burst
E0048306molecular_functioncalcium-dependent protein binding
E0048471cellular_componentperinuclear region of cytoplasm
E0048873biological_processhomeostasis of number of cells within a tissue
E0050885biological_processneuromuscular process controlling balance
E0050905biological_processneuromuscular process
E0051932biological_processsynaptic transmission, GABAergic
E0060326biological_processcell chemotaxis
E0070062cellular_componentextracellular exosome
E0071944cellular_componentcell periphery
E0098794cellular_componentpostsynapse
E0098974biological_processpostsynaptic actin cytoskeleton organization
E0098978cellular_componentglutamatergic synapse
E0150052biological_processregulation of postsynapse assembly
E1900026biological_processpositive regulation of substrate adhesion-dependent cell spreading
E1902622biological_processregulation of neutrophil migration
F0003924molecular_functionGTPase activity
F0003925molecular_functionG protein activity
F0005515molecular_functionprotein binding
F0005525molecular_functionGTP binding
F0005737cellular_componentcytoplasm
F0005789cellular_componentendoplasmic reticulum membrane
F0005829cellular_componentcytosol
F0005856cellular_componentcytoskeleton
F0005886cellular_componentplasma membrane
F0007015biological_processactin filament organization
F0007163biological_processestablishment or maintenance of cell polarity
F0007264biological_processsmall GTPase-mediated signal transduction
F0008045biological_processmotor neuron axon guidance
F0008360biological_processregulation of cell shape
F0012505cellular_componentendomembrane system
F0014041biological_processregulation of neuron maturation
F0016055biological_processWnt signaling pathway
F0016601biological_processRac protein signal transduction
F0016787molecular_functionhydrolase activity
F0019901molecular_functionprotein kinase binding
F0021894biological_processcerebral cortex GABAergic interneuron development
F0022604biological_processregulation of cell morphogenesis
F0030027cellular_componentlamellipodium
F0030031biological_processcell projection assembly
F0030036biological_processactin cytoskeleton organization
F0030426cellular_componentgrowth cone
F0030865biological_processcortical cytoskeleton organization
F0031175biological_processneuron projection development
F0031410cellular_componentcytoplasmic vesicle
F0031941cellular_componentfilamentous actin
F0032956biological_processregulation of actin cytoskeleton organization
F0033630biological_processpositive regulation of cell adhesion mediated by integrin
F0035556biological_processintracellular signal transduction
F0042995cellular_componentcell projection
F0043005cellular_componentneuron projection
F0043020cellular_componentNADPH oxidase complex
F0043025cellular_componentneuronal cell body
F0043652biological_processengulfment of apoptotic cell
F0045730biological_processrespiratory burst
F0048306molecular_functioncalcium-dependent protein binding
F0048471cellular_componentperinuclear region of cytoplasm
F0048873biological_processhomeostasis of number of cells within a tissue
F0050885biological_processneuromuscular process controlling balance
F0050905biological_processneuromuscular process
F0051932biological_processsynaptic transmission, GABAergic
F0060326biological_processcell chemotaxis
F0070062cellular_componentextracellular exosome
F0071944cellular_componentcell periphery
F0098794cellular_componentpostsynapse
F0098974biological_processpostsynaptic actin cytoskeleton organization
F0098978cellular_componentglutamatergic synapse
F0150052biological_processregulation of postsynapse assembly
F1900026biological_processpositive regulation of substrate adhesion-dependent cell spreading
F1902622biological_processregulation of neutrophil migration
G0003924molecular_functionGTPase activity
G0003925molecular_functionG protein activity
G0005515molecular_functionprotein binding
G0005525molecular_functionGTP binding
G0005737cellular_componentcytoplasm
G0005789cellular_componentendoplasmic reticulum membrane
G0005829cellular_componentcytosol
G0005856cellular_componentcytoskeleton
G0005886cellular_componentplasma membrane
G0007015biological_processactin filament organization
G0007163biological_processestablishment or maintenance of cell polarity
G0007264biological_processsmall GTPase-mediated signal transduction
G0008045biological_processmotor neuron axon guidance
G0008360biological_processregulation of cell shape
G0012505cellular_componentendomembrane system
G0014041biological_processregulation of neuron maturation
G0016055biological_processWnt signaling pathway
G0016601biological_processRac protein signal transduction
G0016787molecular_functionhydrolase activity
G0019901molecular_functionprotein kinase binding
G0021894biological_processcerebral cortex GABAergic interneuron development
G0022604biological_processregulation of cell morphogenesis
G0030027cellular_componentlamellipodium
G0030031biological_processcell projection assembly
G0030036biological_processactin cytoskeleton organization
G0030426cellular_componentgrowth cone
G0030865biological_processcortical cytoskeleton organization
G0031175biological_processneuron projection development
G0031410cellular_componentcytoplasmic vesicle
G0031941cellular_componentfilamentous actin
G0032956biological_processregulation of actin cytoskeleton organization
G0033630biological_processpositive regulation of cell adhesion mediated by integrin
G0035556biological_processintracellular signal transduction
G0042995cellular_componentcell projection
G0043005cellular_componentneuron projection
G0043020cellular_componentNADPH oxidase complex
G0043025cellular_componentneuronal cell body
G0043652biological_processengulfment of apoptotic cell
G0045730biological_processrespiratory burst
G0048306molecular_functioncalcium-dependent protein binding
G0048471cellular_componentperinuclear region of cytoplasm
G0048873biological_processhomeostasis of number of cells within a tissue
G0050885biological_processneuromuscular process controlling balance
G0050905biological_processneuromuscular process
G0051932biological_processsynaptic transmission, GABAergic
G0060326biological_processcell chemotaxis
G0070062cellular_componentextracellular exosome
G0071944cellular_componentcell periphery
G0098794cellular_componentpostsynapse
G0098974biological_processpostsynaptic actin cytoskeleton organization
G0098978cellular_componentglutamatergic synapse
G0150052biological_processregulation of postsynapse assembly
G1900026biological_processpositive regulation of substrate adhesion-dependent cell spreading
G1902622biological_processregulation of neutrophil migration
H0003924molecular_functionGTPase activity
H0003925molecular_functionG protein activity
H0005515molecular_functionprotein binding
H0005525molecular_functionGTP binding
H0005737cellular_componentcytoplasm
H0005789cellular_componentendoplasmic reticulum membrane
H0005829cellular_componentcytosol
H0005856cellular_componentcytoskeleton
H0005886cellular_componentplasma membrane
H0007015biological_processactin filament organization
H0007163biological_processestablishment or maintenance of cell polarity
H0007264biological_processsmall GTPase-mediated signal transduction
H0008045biological_processmotor neuron axon guidance
H0008360biological_processregulation of cell shape
H0012505cellular_componentendomembrane system
H0014041biological_processregulation of neuron maturation
H0016055biological_processWnt signaling pathway
H0016601biological_processRac protein signal transduction
H0016787molecular_functionhydrolase activity
H0019901molecular_functionprotein kinase binding
H0021894biological_processcerebral cortex GABAergic interneuron development
H0022604biological_processregulation of cell morphogenesis
H0030027cellular_componentlamellipodium
H0030031biological_processcell projection assembly
H0030036biological_processactin cytoskeleton organization
H0030426cellular_componentgrowth cone
H0030865biological_processcortical cytoskeleton organization
H0031175biological_processneuron projection development
H0031410cellular_componentcytoplasmic vesicle
H0031941cellular_componentfilamentous actin
H0032956biological_processregulation of actin cytoskeleton organization
H0033630biological_processpositive regulation of cell adhesion mediated by integrin
H0035556biological_processintracellular signal transduction
H0042995cellular_componentcell projection
H0043005cellular_componentneuron projection
H0043020cellular_componentNADPH oxidase complex
H0043025cellular_componentneuronal cell body
H0043652biological_processengulfment of apoptotic cell
H0045730biological_processrespiratory burst
H0048306molecular_functioncalcium-dependent protein binding
H0048471cellular_componentperinuclear region of cytoplasm
H0048873biological_processhomeostasis of number of cells within a tissue
H0050885biological_processneuromuscular process controlling balance
H0050905biological_processneuromuscular process
H0051932biological_processsynaptic transmission, GABAergic
H0060326biological_processcell chemotaxis
H0070062cellular_componentextracellular exosome
H0071944cellular_componentcell periphery
H0098794cellular_componentpostsynapse
H0098974biological_processpostsynaptic actin cytoskeleton organization
H0098978cellular_componentglutamatergic synapse
H0150052biological_processregulation of postsynapse assembly
H1900026biological_processpositive regulation of substrate adhesion-dependent cell spreading
H1902622biological_processregulation of neutrophil migration
I0004674molecular_functionprotein serine/threonine kinase activity
J0004674molecular_functionprotein serine/threonine kinase activity
K0004674molecular_functionprotein serine/threonine kinase activity
L0004674molecular_functionprotein serine/threonine kinase activity
M0004674molecular_functionprotein serine/threonine kinase activity
N0004674molecular_functionprotein serine/threonine kinase activity
O0004674molecular_functionprotein serine/threonine kinase activity
P0004674molecular_functionprotein serine/threonine kinase activity
Functional Information from PDB Data
site_idAC1
Number of Residues5
DetailsBINDING SITE FOR RESIDUE MG A 202
ChainResidue
ATHR17
ATHR35
AGCP200
AHOH1222
AHOH1250

site_idAC2
Number of Residues5
DetailsBINDING SITE FOR RESIDUE MG F 202
ChainResidue
FHOH1334
FTHR17
FTHR35
FGCP200
FHOH1302

site_idAC3
Number of Residues5
DetailsBINDING SITE FOR RESIDUE MG B 202
ChainResidue
BTHR17
BTHR35
BGCP200
BHOH1220
BHOH1253

site_idAC4
Number of Residues5
DetailsBINDING SITE FOR RESIDUE MG C 202
ChainResidue
CTHR17
CTHR35
CGCP200
CHOH1308
CHOH1360

site_idAC5
Number of Residues5
DetailsBINDING SITE FOR RESIDUE MG G 202
ChainResidue
GTHR17
GTHR35
GGCP200
GHOH236
GHOH249

site_idAC6
Number of Residues5
DetailsBINDING SITE FOR RESIDUE MG D 202
ChainResidue
DTHR17
DTHR35
DGCP200
DHOH1317
DHOH1328

site_idAC7
Number of Residues5
DetailsBINDING SITE FOR RESIDUE MG E 202
ChainResidue
ETHR17
ETHR35
EGCP200
EHOH1242
EHOH1249

site_idAC8
Number of Residues5
DetailsBINDING SITE FOR RESIDUE MG H 202
ChainResidue
HTHR17
HTHR35
HGCP200
HHOH217
HHOH263

site_idAC9
Number of Residues1
DetailsBINDING SITE FOR RESIDUE CL A 1201
ChainResidue
ASER151

site_idBC1
Number of Residues2
DetailsBINDING SITE FOR RESIDUE CL C 1203
ChainResidue
BHOH1213
CARG102

site_idBC2
Number of Residues2
DetailsBINDING SITE FOR RESIDUE CL B 1204
ChainResidue
BSER22
BLEU160

site_idBC3
Number of Residues1
DetailsBINDING SITE FOR RESIDUE CL P 1205
ChainResidue
PGLN27

site_idBC4
Number of Residues1
DetailsBINDING SITE FOR RESIDUE CL N 1206
ChainResidue
NPRO14

site_idBC5
Number of Residues2
DetailsBINDING SITE FOR RESIDUE CL O 1209
ChainResidue
OGLN27
OHOH759

site_idBC6
Number of Residues30
DetailsBINDING SITE FOR RESIDUE GCP A 200
ChainResidue
AALA13
AVAL14
AGLY15
ALYS16
ATHR17
ACYS18
APHE28
ATYR32
APRO34
ATHR35
AGLY60
ALYS116
AASP118
ALEU119
ASER158
AALA159
ALEU160
AMG202
AHOH1208
AHOH1209
AHOH1210
AHOH1221
AHOH1222
AHOH1227
AHOH1234
AHOH1250
AHOH1254
AHOH1283
AHOH1290
JGLN27

site_idBC7
Number of Residues29
DetailsBINDING SITE FOR RESIDUE GCP F 200
ChainResidue
FHOH1303
FHOH1319
FHOH1332
FHOH1333
FHOH1334
FHOH1335
GHOH207
OGLN27
OHOH586
FALA13
FVAL14
FGLY15
FLYS16
FTHR17
FCYS18
FPHE28
FTYR32
FPRO34
FTHR35
FGLY60
FLYS116
FASP118
FLEU119
FSER158
FALA159
FLEU160
FMG202
FEDO1301
FHOH1302

site_idBC8
Number of Residues28
DetailsBINDING SITE FOR RESIDUE GCP B 200
ChainResidue
AHOH1241
BALA13
BVAL14
BGLY15
BLYS16
BTHR17
BCYS18
BPHE28
BTYR32
BPRO34
BTHR35
BGLY60
BLYS116
BASP118
BLEU119
BSER158
BALA159
BLEU160
BMG202
BHOH1205
BHOH1209
BHOH1219
BHOH1220
BHOH1226
BHOH1228
BHOH1232
BHOH1253
IGLN27

site_idBC9
Number of Residues28
DetailsBINDING SITE FOR RESIDUE GCP C 200
ChainResidue
CALA13
CVAL14
CGLY15
CLYS16
CTHR17
CCYS18
CPHE28
CTYR32
CPRO34
CTHR35
CGLY60
CLYS116
CASP118
CLEU119
CSER158
CALA159
CLEU160
CMG202
CEDO1302
CHOH1303
CHOH1307
CHOH1308
CHOH1321
CHOH1330
CHOH1338
CHOH1339
CHOH1360
LGLN27

site_idCC1
Number of Residues29
DetailsBINDING SITE FOR RESIDUE GCP G 200
ChainResidue
FHOH1304
GALA13
GVAL14
GGLY15
GLYS16
GTHR17
GCYS18
GPHE28
GTYR32
GPRO34
GTHR35
GGLY60
GLYS116
GASP118
GLEU119
GSER158
GALA159
GLEU160
GMG202
GHOH203
GHOH204
GHOH213
GHOH221
GHOH225
GHOH236
GHOH237
GHOH249
NGLN27
NHOH530

site_idCC2
Number of Residues27
DetailsBINDING SITE FOR RESIDUE GCP D 200
ChainResidue
DALA13
DVAL14
DGLY15
DLYS16
DTHR17
DCYS18
DPHE28
DTYR32
DPRO34
DTHR35
DGLY60
DLYS116
DASP118
DSER158
DALA159
DLEU160
DMG202
DEDO1303
DHOH1305
DHOH1317
DHOH1328
DHOH1330
DHOH1333
DHOH1334
DHOH1339
DHOH1340
KGLN27

site_idCC3
Number of Residues28
DetailsBINDING SITE FOR RESIDUE GCP E 200
ChainResidue
EALA13
EVAL14
EGLY15
ELYS16
ETHR17
ECYS18
EPHE28
ETYR32
EPRO34
ETHR35
EGLY60
ELYS116
EASP118
ELEU119
ESER158
EALA159
ELEU160
EMG202
EHOH1209
EHOH1213
EHOH1215
EHOH1216
EHOH1240
EHOH1242
EHOH1249
EHOH1259
HHOH208
PGLN27

site_idCC4
Number of Residues30
DetailsBINDING SITE FOR RESIDUE GCP H 200
ChainResidue
EHOH1225
HALA13
HVAL14
HGLY15
HLYS16
HTHR17
HCYS18
HPHE28
HTYR32
HPRO34
HTHR35
HGLY60
HLYS116
HASP118
HLEU119
HSER158
HALA159
HLEU160
HMG202
HHOH207
HHOH215
HHOH217
HHOH219
HHOH225
HHOH239
HHOH247
HHOH263
HHOH306
MGLN27
MHOH595

site_idCC5
Number of Residues6
DetailsBINDING SITE FOR RESIDUE EDO F 1301
ChainResidue
FPRO29
FGLU31
FTYR32
FILE33
FGCP200
FHOH1373

site_idCC6
Number of Residues6
DetailsBINDING SITE FOR RESIDUE EDO C 1302
ChainResidue
CTHR17
CGLU31
CTYR32
CILE33
CGCP200
CHOH1407

site_idCC7
Number of Residues6
DetailsBINDING SITE FOR RESIDUE EDO D 1303
ChainResidue
DTHR17
DGLU31
DTYR32
DILE33
DGCP200
DHOH1364

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues8
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:18691976, ECO:0007744|PubMed:19369195, ECO:0007744|PubMed:23186163
ChainResidueDetails
ISER41
CGLY10
CASP57
CTHR115
GGLY10
GASP57
GTHR115
DGLY10
DASP57
DTHR115
EGLY10
JSER41
EASP57
ETHR115
HGLY10
HASP57
HTHR115
KSER41
LSER41
MSER41
NSER41
OSER41
PSER41
BTHR115

site_idSWS_FT_FI2
Number of Residues8
DetailsCARBOHYD: O-linked (GlcNAc) tyrosine; by Photorhabdus PAU_02230 => ECO:0000269|PubMed:24141704
ChainResidueDetails
ATYR32
FTYR32
BTYR32
CTYR32
GTYR32
DTYR32
ETYR32
HTYR32

site_idSWS_FT_FI3
Number of Residues16
DetailsCROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:24684802
ChainResidueDetails
ALYS166
DLYS166
ELYS166
HLYS166
FLYS166
BLYS166
CLYS166
GLYS166

Catalytic Information from CSA
site_idCSA1
Number of Residues1
DetailsAnnotated By Reference To The Literature 1ksj
ChainResidueDetails
AGLN61

site_idCSA2
Number of Residues1
DetailsAnnotated By Reference To The Literature 1ksj
ChainResidueDetails
FGLN61

site_idCSA3
Number of Residues1
DetailsAnnotated By Reference To The Literature 1ksj
ChainResidueDetails
BGLN61

site_idCSA4
Number of Residues1
DetailsAnnotated By Reference To The Literature 1ksj
ChainResidueDetails
CGLN61

site_idCSA5
Number of Residues1
DetailsAnnotated By Reference To The Literature 1ksj
ChainResidueDetails
GGLN61

site_idCSA6
Number of Residues1
DetailsAnnotated By Reference To The Literature 1ksj
ChainResidueDetails
DGLN61

site_idCSA7
Number of Residues1
DetailsAnnotated By Reference To The Literature 1ksj
ChainResidueDetails
EGLN61

site_idCSA8
Number of Residues1
DetailsAnnotated By Reference To The Literature 1ksj
ChainResidueDetails
HGLN61

224931

PDB entries from 2024-09-11

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