2ORL

Solution structure of the cytochrome c- para-aminophenol adduct

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Functional Information from GO Data

ChainGOidnamespacecontents
A0005758cellular_componentmitochondrial intermembrane space
A0005739cellular_componentmitochondrion
A0070469cellular_componentrespiratory chain
A0009055molecular_functionelectron transfer activity
A0020037molecular_functionheme binding
A0046872molecular_functionmetal ion binding
A0006123biological_processmitochondrial electron transport, cytochrome c to oxygen
A0006122biological_processmitochondrial electron transport, ubiquinol to cytochrome c
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Functional Information from PDB Data

site_idNumber of ResiduesDetails
AC122BINDING SITE FOR RESIDUE HEC A 104
ChainResidue
AARG13
ACYS14
AGLN16
ACYS17
AHIS18
AVAL28
APRO30
ALEU32
AILE35
ASER40
AGLY41
AGLN42
ATYR46
ATYR48
ATHR49
AASN52
ATRP59
ALEU68
ATHR78
ALYS79
AMET80
APHE82

AC25BINDING SITE FOR RESIDUE 4NL A 105
ChainResidue
APHE36
AASP60
AGLU61
ALYS99
AGLU103

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Functional Information from PDB atom coordinates for the "HETATM" binding sites

site_idNumber of ResiduesDetails
HEC_2orl_A_10440HEME C binding site
ChainResidueligand
APHE10HEC: HEME C
AARG13-HIS18HEC: HEME C
AVAL28-LEU32HEC: HEME C
AILE35HEC: HEME C
AHIS39-ALA43HEC: HEME C
ATYR46-THR49HEC: HEME C
AASN52HEC: HEME C
ATRP59HEC: HEME C
AMET64HEC: HEME C
ATYR67-LEU68HEC: HEME C
AILE75HEC: HEME C
AGLY77-PHE82HEC: HEME C
AGLY84-LEU85HEC: HEME C
ALEU94HEC: HEME C
ALEU98HEC: HEME C
ALEU9HEC: HEME C
AARG38HEC: HEME C

4NL_2orl_A_105154-AMINOPHENOL binding site
ChainResidueligand
APHE36-ARG384NL: 4-AMINOPHENOL
ALEU58-ASN624NL: 4-AMINOPHENOL
AILE954NL: 4-AMINOPHENOL
ALEU98-LYS994NL: 4-AMINOPHENOL
ATHR102-GLU1034NL: 4-AMINOPHENOL
AMET644NL: 4-AMINOPHENOL
ALYS1004NL: 4-AMINOPHENOL

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Functional Information from PROSITE/UniProt

site_idNumber of ResiduesDetails
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Functional Information from SwissProt/UniProt

site_idNumber of ResiduesDetails
SWS_FT_FI12Iron (heme axial ligand)
ChainResidueDetails
AHIS23
AMET85

SWS_FT_FI22Heme (covalent).
ChainResidueDetails
ACYS19
ACYS22

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Catalytic Information from CSA

site_idNumber of ResiduesDetails