Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

2ON5

Structure of NaGST-2

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004364	molecular_function	glutathione transferase activity
A	0006749	biological_process	glutathione metabolic process
A	0016740	molecular_function	transferase activity
B	0004364	molecular_function	glutathione transferase activity
B	0006749	biological_process	glutathione metabolic process
B	0016740	molecular_function	transferase activity
C	0004364	molecular_function	glutathione transferase activity
C	0006749	biological_process	glutathione metabolic process
C	0016740	molecular_function	transferase activity
D	0004364	molecular_function	glutathione transferase activity
D	0006749	biological_process	glutathione metabolic process
D	0016740	molecular_function	transferase activity
E	0004364	molecular_function	glutathione transferase activity
E	0006749	biological_process	glutathione metabolic process
E	0016740	molecular_function	transferase activity
F	0004364	molecular_function	glutathione transferase activity
F	0006749	biological_process	glutathione metabolic process
F	0016740	molecular_function	transferase activity
G	0004364	molecular_function	glutathione transferase activity
G	0006749	biological_process	glutathione metabolic process
G	0016740	molecular_function	transferase activity
H	0004364	molecular_function	glutathione transferase activity
H	0006749	biological_process	glutathione metabolic process
H	0016740	molecular_function	transferase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE EDO A 419

Chain	Residue
A	ARG129
A	GLU130

site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE EDO A 420

Chain	Residue
A	PHE9
A	ALA10
A	TYR34
A	THR35
A	PHE36

site_id	AC3
Number of Residues	1
Details	BINDING SITE FOR RESIDUE EDO A 421

Chain	Residue
A	HOH1214

site_id	AC4
Number of Residues	7
Details	BINDING SITE FOR RESIDUE EDO A 422

Chain	Residue
A	VAL109
A	GLY166
A	ILE167
A	LYS205
A	HOH1135
A	HOH1176
A	TYR105

site_id	AC5
Number of Residues	2
Details	BINDING SITE FOR RESIDUE EDO A 423

Chain	Residue
A	GSH999
A	HOH1133

site_id	AC6
Number of Residues	2
Details	BINDING SITE FOR RESIDUE EDO A 424

Chain	Residue
A	ALA110
A	GSH999

site_id	AC7
Number of Residues	5
Details	BINDING SITE FOR RESIDUE EDO A 425

Chain	Residue
A	LEU14
A	ILE18
A	SER64
A	CYS159
A	EDO426

site_id	AC8
Number of Residues	7
Details	BINDING SITE FOR RESIDUE EDO A 426

Chain	Residue
A	LEU14
A	PHE65
A	TYR95
A	EDO425
A	HOH1102
A	HOH1178
A	HOH1197

site_id	AC9
Number of Residues	4
Details	BINDING SITE FOR RESIDUE EDO A 427

Chain	Residue
A	TYR29
A	ASP31
A	TRP197
A	HOH1166

site_id	BC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE EDO A 428

Chain	Residue
A	ALA25
A	GLY26
A	GLN27

site_id	BC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE EDO A 429

Chain	Residue
A	GLN37
A	HOH1041
A	HOH1069
A	HOH1112
A	HOH1221

site_id	BC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE EDO A 452

Chain	Residue
A	LYS138
A	PHE139
A	LYS142
A	HOH1113
G	HOH1148

site_id	BC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE EDO A 454

Chain	Residue
A	ASP44
A	GLU45
A	MET46
A	PRO47
A	GLN60
G	EDO452

site_id	BC5
Number of Residues	13
Details	BINDING SITE FOR RESIDUE GSH A 999

Chain	Residue
A	TYR8
A	PHE9
A	LEU14
A	TRP39
A	LYS43
A	GLN50
A	ILE51
A	GLN63
A	SER64
A	EDO423
A	EDO424
A	HOH1002
G	ASP97

site_id	BC6
Number of Residues	2
Details	BINDING SITE FOR RESIDUE EDO B 419

Chain	Residue
B	ARG129
B	GLU130

site_id	BC7
Number of Residues	5
Details	BINDING SITE FOR RESIDUE EDO B 420

Chain	Residue
B	PHE9
B	ALA10
B	TYR34
B	THR35
B	PHE36

site_id	BC8
Number of Residues	2
Details	BINDING SITE FOR RESIDUE EDO B 421

Chain	Residue
B	LYS205
B	HOH1195

site_id	BC9
Number of Residues	7
Details	BINDING SITE FOR RESIDUE EDO B 422

Chain	Residue
B	TYR105
B	VAL109
B	GLY166
B	ILE167
B	LYS205
B	HOH1081
B	HOH1104

site_id	CC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE EDO B 423

Chain	Residue
B	ARG107
B	VAL112
B	GSH999

site_id	CC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE EDO B 424

Chain	Residue
B	GSH999
B	HOH1244

site_id	CC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE EDO B 425

Chain	Residue
B	LEU14
B	PRO17
B	SER64
B	PHE65
B	EDO426

site_id	CC4
Number of Residues	7
Details	BINDING SITE FOR RESIDUE EDO B 426

Chain	Residue
B	HOH1184
B	LEU14
B	PHE65
B	TYR95
B	EDO425
B	HOH1114
B	HOH1151

site_id	CC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE EDO B 427

Chain	Residue
B	TYR29
B	TRP197
B	HOH1125
B	HOH1185

site_id	CC6
Number of Residues	3
Details	BINDING SITE FOR RESIDUE EDO B 428

Chain	Residue
B	ALA25
B	GLY26
B	GLN27

site_id	CC7
Number of Residues	5
Details	BINDING SITE FOR RESIDUE EDO B 430

Chain	Residue
B	GLN37
B	HOH1039
B	HOH1099
B	HOH1213
E	HOH1079

site_id	CC8
Number of Residues	6
Details	BINDING SITE FOR RESIDUE EDO B 452

Chain	Residue
B	LYS138
B	PHE139
B	LYS142
B	HOH1108
B	HOH1153
C	HOH1085

site_id	CC9
Number of Residues	6
Details	BINDING SITE FOR RESIDUE EDO B 453

Chain	Residue
B	GLN60
B	HOH1034
B	HOH1049
B	HOH1072
B	HOH1124
C	EDO452

site_id	DC1
Number of Residues	13
Details	BINDING SITE FOR RESIDUE GSH B 999

Chain	Residue
B	TYR8
B	PHE9
B	LEU14
B	TRP39
B	LYS43
B	GLN50
B	ILE51
B	GLN63
B	SER64
B	EDO423
B	EDO424
B	HOH1001
C	ASP97

site_id	DC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE EDO C 424

Chain	Residue
C	GLN37
C	PRO40
C	HOH1210
G	ARG107
G	VAL112
G	ASP113

site_id	DC3
Number of Residues	7
Details	BINDING SITE FOR RESIDUE EDO C 425

Chain	Residue
C	LEU14
C	PRO17
C	ILE18
C	SER64
C	PHE65
C	CYS159
C	HOH1117

site_id	DC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE EDO C 427

Chain	Residue
C	TYR29
C	TRP197
C	HOH1120

site_id	DC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE EDO C 428

Chain	Residue
C	ALA25
C	GLY26
C	GLN27
C	HOH1041

site_id	DC6
Number of Residues	6
Details	BINDING SITE FOR RESIDUE EDO C 452

Chain	Residue
B	EDO453
B	HOH1124
C	LYS138
C	PHE139
C	LYS142
C	HOH1233

site_id	DC7
Number of Residues	11
Details	BINDING SITE FOR RESIDUE GSH C 999

Chain	Residue
B	ASP97
C	TYR8
C	PHE9
C	LEU14
C	TRP39
C	LYS43
C	GLN50
C	ILE51
C	GLN63
C	SER64
C	HOH1022

site_id	DC8
Number of Residues	7
Details	BINDING SITE FOR RESIDUE EDO D 418

Chain	Residue
A	ARG33
A	TYR34
A	HOH1087
D	HIS3
D	GLU30
D	HOH1011
D	HOH1047

site_id	DC9
Number of Residues	2
Details	BINDING SITE FOR RESIDUE EDO D 419

Chain	Residue
D	PRO179
F	HOH1155

site_id	EC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE EDO D 422

Chain	Residue
D	ARG189
D	ARG201
D	HOH1017
D	HOH1107
D	HOH1156

site_id	EC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE EDO D 425

Chain	Residue
D	LEU14
D	PRO17
D	SER64
D	PHE65
D	CYS159
D	EDO426

site_id	EC3
Number of Residues	9
Details	BINDING SITE FOR RESIDUE EDO D 426

Chain	Residue
D	GLY13
D	LEU14
D	PRO17
D	TYR95
D	EDO425
D	HOH1082
D	HOH1086
D	HOH1097
D	HOH1153

site_id	EC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE EDO D 427

Chain	Residue
A	LYS41
A	HOH1069
D	TYR29
D	ASP31
D	TRP197
D	HOH1070

site_id	EC5
Number of Residues	5
Details	BINDING SITE FOR RESIDUE EDO D 428

Chain	Residue
D	GLY26
D	GLN27
D	LYS28
D	HOH1112
D	HOH1179

site_id	EC6
Number of Residues	5
Details	BINDING SITE FOR RESIDUE EDO D 453

Chain	Residue
D	LYS59
D	GLN60
D	EDO454
D	HOH1089
F	EDO452

site_id	EC7
Number of Residues	8
Details	BINDING SITE FOR RESIDUE EDO D 454

Chain	Residue
D	ASP44
D	GLU45
D	MET46
D	PRO47
D	GLN60
D	EDO453
F	LYS138
F	EDO452

site_id	EC8
Number of Residues	12
Details	BINDING SITE FOR RESIDUE GSH D 999

Chain	Residue
D	TYR8
D	PHE9
D	LEU14
D	TRP39
D	LYS43
D	GLN50
D	ILE51
D	PRO52
D	GLN63
D	SER64
D	HOH1004
F	ASP97

site_id	EC9
Number of Residues	6
Details	BINDING SITE FOR RESIDUE EDO E 425

Chain	Residue
E	LEU14
E	PRO17
E	ILE18
E	SER64
E	PHE65
E	EDO426

site_id	FC1
Number of Residues	8
Details	BINDING SITE FOR RESIDUE EDO E 426

Chain	Residue
E	GLY13
E	LEU14
E	PRO17
E	TYR95
E	ILE99
E	EDO425
E	HOH1101
E	HOH1111

site_id	FC2
Number of Residues	7
Details	BINDING SITE FOR RESIDUE EDO E 427

Chain	Residue
B	LYS41
B	HOH1039
E	TYR29
E	ASP31
E	TRP197
E	HOH1050
E	HOH1079

site_id	FC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE EDO E 428

Chain	Residue
E	GLY26
E	GLN27
E	LYS28
E	HOH1087

site_id	FC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE EDO E 453

Chain	Residue
E	LYS59
E	GLN60
E	EDO454
H	EDO451
H	EDO452

site_id	FC5
Number of Residues	9
Details	BINDING SITE FOR RESIDUE EDO E 454

Chain	Residue
E	ASP44
E	GLU45
E	MET46
E	PRO47
E	GLN60
E	EDO453
E	HOH1187
H	LYS138
H	EDO452

site_id	FC6
Number of Residues	6
Details	BINDING SITE FOR RESIDUE EDO E 450

Chain	Residue
E	PHE83
E	LEU87
E	LYS142
E	HOH1103
H	LYS59
H	GLN60

site_id	FC7
Number of Residues	3
Details	BINDING SITE FOR RESIDUE EDO E 452

Chain	Residue
E	LYS142
E	HOH1084
E	HOH1103

site_id	FC8
Number of Residues	15
Details	BINDING SITE FOR RESIDUE GSH E 999

Chain	Residue
E	TYR8
E	PHE9
E	LEU14
E	TRP39
E	LYS43
E	GLN50
E	ILE51
E	PRO52
E	GLN63
E	SER64
E	HOH1009
E	HOH1019
E	HOH1148
E	HOH1150
H	ASP97

site_id	FC9
Number of Residues	5
Details	BINDING SITE FOR RESIDUE EDO F 418

Chain	Residue
D	LYS182
F	LEU126
F	ARG129
F	ASP176
F	HOH1153

site_id	GC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE EDO F 419

Chain	Residue
F	PRO40
F	HOH1038
F	HOH1175

site_id	GC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE EDO F 420

Chain	Residue
F	PHE9
F	ALA10
F	TYR34
F	THR35
F	PHE36
F	HOH1189

site_id	GC3
Number of Residues	8
Details	BINDING SITE FOR RESIDUE EDO F 422

Chain	Residue
F	LEU106
F	VAL109
F	ILE167
F	LYS205
F	HOH1082
F	HOH1083
F	HOH1112
F	HOH1178

site_id	GC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE EDO F 424

Chain	Residue
F	PHE9
F	TRP39
F	VAL112
F	HOH1180

site_id	GC5
Number of Residues	5
Details	BINDING SITE FOR RESIDUE EDO F 425

Chain	Residue
F	LEU14
F	PRO17
F	ILE18
F	SER64
F	PHE65

site_id	GC6
Number of Residues	3
Details	BINDING SITE FOR RESIDUE EDO F 427

Chain	Residue
F	TYR29
F	TRP197
F	HOH1068

site_id	GC7
Number of Residues	2
Details	BINDING SITE FOR RESIDUE EDO F 432

Chain	Residue
F	GLU30
F	ASP31

site_id	GC8
Number of Residues	5
Details	BINDING SITE FOR RESIDUE EDO F 450

Chain	Residue
F	SER143
F	VAL149
F	GLY150
F	EDO451
F	HOH1022

site_id	GC9
Number of Residues	7
Details	BINDING SITE FOR RESIDUE EDO F 451

Chain	Residue
D	HOH1025
F	LEU87
F	PHE139
F	LYS142
F	EDO450
F	EDO452
F	HOH1022

site_id	HC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE EDO F 452

Chain	Residue
D	EDO453
D	EDO454
F	LYS138
F	PHE139
F	LYS142
F	EDO451

site_id	HC2
Number of Residues	14
Details	BINDING SITE FOR RESIDUE GSH F 999

Chain	Residue
D	ASP97
F	TYR8
F	PHE9
F	LEU14
F	TRP39
F	LYS43
F	GLN50
F	ILE51
F	PRO52
F	GLN63
F	SER64
F	HOH1029
F	HOH1163
F	HOH1180

site_id	HC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE EDO G 420

Chain	Residue
C	GLN114
G	ALA10
G	THR204
G	LYS205
G	HOH1122
G	HOH1221

site_id	HC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE EDO G 422

Chain	Residue
G	LEU106
G	VAL109
G	ALA110
G	HOH1063

site_id	HC5
Number of Residues	6
Details	BINDING SITE FOR RESIDUE EDO G 425

Chain	Residue
G	LEU14
G	PRO17
G	ILE18
G	SER64
G	PHE65
G	EDO426

site_id	HC6
Number of Residues	10
Details	BINDING SITE FOR RESIDUE EDO G 426

Chain	Residue
G	GLY13
G	LEU14
G	PRO17
G	TYR95
G	ILE99
G	EDO425
G	HOH1023
G	HOH1076
G	HOH1085
G	HOH1185

site_id	HC7
Number of Residues	3
Details	BINDING SITE FOR RESIDUE EDO G 427

Chain	Residue
G	TYR29
G	TRP197
G	HOH1097

site_id	HC8
Number of Residues	7
Details	BINDING SITE FOR RESIDUE EDO G 450

Chain	Residue
G	LEU87
G	LYS142
G	HOH1017
G	HOH1041
G	HOH1100
G	HOH1104
G	HOH1197

site_id	HC9
Number of Residues	3
Details	BINDING SITE FOR RESIDUE EDO G 452

Chain	Residue
A	EDO454
G	LYS142
G	HOH1034

site_id	IC1
Number of Residues	11
Details	BINDING SITE FOR RESIDUE GSH G 999

Chain	Residue
A	ASP97
G	TYR8
G	PHE9
G	LEU14
G	TRP39
G	LYS43
G	GLN50
G	ILE51
G	GLN63
G	SER64
G	HOH1234

site_id	IC2
Number of Residues	8
Details	BINDING SITE FOR RESIDUE EDO H 422

Chain	Residue
H	VAL109
H	ILE167
H	LYS205
H	PHE206
H	HOH1074
H	HOH1106
H	HOH1131
H	HOH1153

site_id	IC3
Number of Residues	2
Details	BINDING SITE FOR RESIDUE EDO H 423

Chain	Residue
H	GLY111
H	VAL112

site_id	IC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE EDO H 425

Chain	Residue
H	LEU14
H	SER64
H	PHE65
H	EDO426

site_id	IC5
Number of Residues	8
Details	BINDING SITE FOR RESIDUE EDO H 426

Chain	Residue
H	GLY13
H	LEU14
H	PRO17
H	TYR95
H	ILE99
H	EDO425
H	HOH1020
H	HOH1095

site_id	IC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE EDO H 427

Chain	Residue
H	LYS28
H	TYR29
H	EDO429
H	HOH1177

site_id	IC7
Number of Residues	7
Details	BINDING SITE FOR RESIDUE EDO H 429

Chain	Residue
H	PHE22
H	ALA23
H	GLN27
H	TYR29
H	TRP197
H	EDO427
H	HOH1026

site_id	IC8
Number of Residues	6
Details	BINDING SITE FOR RESIDUE EDO H 450

Chain	Residue
H	PHE139
H	SER143
H	LEU148
H	VAL149
H	GLY150
H	EDO451

site_id	IC9
Number of Residues	7
Details	BINDING SITE FOR RESIDUE EDO H 451

Chain	Residue
E	EDO453
H	LEU87
H	PHE139
H	LYS142
H	EDO450
H	EDO452
H	HOH1009

site_id	JC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE EDO H 452

Chain	Residue
E	EDO453
E	EDO454
H	PHE139
H	LYS142
H	EDO451

site_id	JC2
Number of Residues	12
Details	BINDING SITE FOR RESIDUE GSH H 999

Chain	Residue
E	ASP97
H	TYR8
H	PHE9
H	LEU14
H	TRP39
H	LYS43
H	GLN50
H	ILE51
H	GLN63
H	SER64
H	HOH1006
H	HOH1165

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)