2OJW
Crystal structure of human glutamine synthetase in complex with ADP and phosphate
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0001525 | biological_process | angiogenesis |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0004356 | molecular_function | glutamine synthetase activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005634 | cellular_component | nucleus |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005739 | cellular_component | mitochondrion |
| A | 0005829 | cellular_component | cytosol |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0006538 | biological_process | L-glutamate catabolic process |
| A | 0006542 | biological_process | glutamine biosynthetic process |
| A | 0008283 | biological_process | cell population proliferation |
| A | 0009267 | biological_process | cellular response to starvation |
| A | 0009749 | biological_process | response to glucose |
| A | 0010594 | biological_process | regulation of endothelial cell migration |
| A | 0016740 | molecular_function | transferase activity |
| A | 0016874 | molecular_function | ligase activity |
| A | 0018345 | biological_process | protein palmitoylation |
| A | 0019706 | molecular_function | protein-cysteine S-palmitoyltransferase activity |
| A | 0042254 | biological_process | ribosome biogenesis |
| A | 0042802 | molecular_function | identical protein binding |
| A | 0044297 | cellular_component | cell body |
| A | 0045648 | biological_process | positive regulation of erythrocyte differentiation |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0070062 | cellular_component | extracellular exosome |
| A | 0097275 | biological_process | intracellular ammonium homeostasis |
| A | 0097386 | cellular_component | glial cell projection |
| A | 1903670 | biological_process | regulation of sprouting angiogenesis |
| A | 1904749 | biological_process | regulation of protein localization to nucleolus |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0001525 | biological_process | angiogenesis |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0004356 | molecular_function | glutamine synthetase activity |
| B | 0005515 | molecular_function | protein binding |
| B | 0005524 | molecular_function | ATP binding |
| B | 0005634 | cellular_component | nucleus |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005739 | cellular_component | mitochondrion |
| B | 0005829 | cellular_component | cytosol |
| B | 0005886 | cellular_component | plasma membrane |
| B | 0006538 | biological_process | L-glutamate catabolic process |
| B | 0006542 | biological_process | glutamine biosynthetic process |
| B | 0008283 | biological_process | cell population proliferation |
| B | 0009267 | biological_process | cellular response to starvation |
| B | 0009749 | biological_process | response to glucose |
| B | 0010594 | biological_process | regulation of endothelial cell migration |
| B | 0016740 | molecular_function | transferase activity |
| B | 0016874 | molecular_function | ligase activity |
| B | 0018345 | biological_process | protein palmitoylation |
| B | 0019706 | molecular_function | protein-cysteine S-palmitoyltransferase activity |
| B | 0042254 | biological_process | ribosome biogenesis |
| B | 0042802 | molecular_function | identical protein binding |
| B | 0044297 | cellular_component | cell body |
| B | 0045648 | biological_process | positive regulation of erythrocyte differentiation |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0070062 | cellular_component | extracellular exosome |
| B | 0097275 | biological_process | intracellular ammonium homeostasis |
| B | 0097386 | cellular_component | glial cell projection |
| B | 1903670 | biological_process | regulation of sprouting angiogenesis |
| B | 1904749 | biological_process | regulation of protein localization to nucleolus |
| C | 0000166 | molecular_function | nucleotide binding |
| C | 0001525 | biological_process | angiogenesis |
| C | 0003824 | molecular_function | catalytic activity |
| C | 0004356 | molecular_function | glutamine synthetase activity |
| C | 0005515 | molecular_function | protein binding |
| C | 0005524 | molecular_function | ATP binding |
| C | 0005634 | cellular_component | nucleus |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0005739 | cellular_component | mitochondrion |
| C | 0005829 | cellular_component | cytosol |
| C | 0005886 | cellular_component | plasma membrane |
| C | 0006538 | biological_process | L-glutamate catabolic process |
| C | 0006542 | biological_process | glutamine biosynthetic process |
| C | 0008283 | biological_process | cell population proliferation |
| C | 0009267 | biological_process | cellular response to starvation |
| C | 0009749 | biological_process | response to glucose |
| C | 0010594 | biological_process | regulation of endothelial cell migration |
| C | 0016740 | molecular_function | transferase activity |
| C | 0016874 | molecular_function | ligase activity |
| C | 0018345 | biological_process | protein palmitoylation |
| C | 0019706 | molecular_function | protein-cysteine S-palmitoyltransferase activity |
| C | 0042254 | biological_process | ribosome biogenesis |
| C | 0042802 | molecular_function | identical protein binding |
| C | 0044297 | cellular_component | cell body |
| C | 0045648 | biological_process | positive regulation of erythrocyte differentiation |
| C | 0046872 | molecular_function | metal ion binding |
| C | 0070062 | cellular_component | extracellular exosome |
| C | 0097275 | biological_process | intracellular ammonium homeostasis |
| C | 0097386 | cellular_component | glial cell projection |
| C | 1903670 | biological_process | regulation of sprouting angiogenesis |
| C | 1904749 | biological_process | regulation of protein localization to nucleolus |
| D | 0000166 | molecular_function | nucleotide binding |
| D | 0001525 | biological_process | angiogenesis |
| D | 0003824 | molecular_function | catalytic activity |
| D | 0004356 | molecular_function | glutamine synthetase activity |
| D | 0005515 | molecular_function | protein binding |
| D | 0005524 | molecular_function | ATP binding |
| D | 0005634 | cellular_component | nucleus |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0005739 | cellular_component | mitochondrion |
| D | 0005829 | cellular_component | cytosol |
| D | 0005886 | cellular_component | plasma membrane |
| D | 0006538 | biological_process | L-glutamate catabolic process |
| D | 0006542 | biological_process | glutamine biosynthetic process |
| D | 0008283 | biological_process | cell population proliferation |
| D | 0009267 | biological_process | cellular response to starvation |
| D | 0009749 | biological_process | response to glucose |
| D | 0010594 | biological_process | regulation of endothelial cell migration |
| D | 0016740 | molecular_function | transferase activity |
| D | 0016874 | molecular_function | ligase activity |
| D | 0018345 | biological_process | protein palmitoylation |
| D | 0019706 | molecular_function | protein-cysteine S-palmitoyltransferase activity |
| D | 0042254 | biological_process | ribosome biogenesis |
| D | 0042802 | molecular_function | identical protein binding |
| D | 0044297 | cellular_component | cell body |
| D | 0045648 | biological_process | positive regulation of erythrocyte differentiation |
| D | 0046872 | molecular_function | metal ion binding |
| D | 0070062 | cellular_component | extracellular exosome |
| D | 0097275 | biological_process | intracellular ammonium homeostasis |
| D | 0097386 | cellular_component | glial cell projection |
| D | 1903670 | biological_process | regulation of sprouting angiogenesis |
| D | 1904749 | biological_process | regulation of protein localization to nucleolus |
| E | 0000166 | molecular_function | nucleotide binding |
| E | 0001525 | biological_process | angiogenesis |
| E | 0003824 | molecular_function | catalytic activity |
| E | 0004356 | molecular_function | glutamine synthetase activity |
| E | 0005515 | molecular_function | protein binding |
| E | 0005524 | molecular_function | ATP binding |
| E | 0005634 | cellular_component | nucleus |
| E | 0005737 | cellular_component | cytoplasm |
| E | 0005739 | cellular_component | mitochondrion |
| E | 0005829 | cellular_component | cytosol |
| E | 0005886 | cellular_component | plasma membrane |
| E | 0006538 | biological_process | L-glutamate catabolic process |
| E | 0006542 | biological_process | glutamine biosynthetic process |
| E | 0008283 | biological_process | cell population proliferation |
| E | 0009267 | biological_process | cellular response to starvation |
| E | 0009749 | biological_process | response to glucose |
| E | 0010594 | biological_process | regulation of endothelial cell migration |
| E | 0016740 | molecular_function | transferase activity |
| E | 0016874 | molecular_function | ligase activity |
| E | 0018345 | biological_process | protein palmitoylation |
| E | 0019706 | molecular_function | protein-cysteine S-palmitoyltransferase activity |
| E | 0042254 | biological_process | ribosome biogenesis |
| E | 0042802 | molecular_function | identical protein binding |
| E | 0044297 | cellular_component | cell body |
| E | 0045648 | biological_process | positive regulation of erythrocyte differentiation |
| E | 0046872 | molecular_function | metal ion binding |
| E | 0070062 | cellular_component | extracellular exosome |
| E | 0097275 | biological_process | intracellular ammonium homeostasis |
| E | 0097386 | cellular_component | glial cell projection |
| E | 1903670 | biological_process | regulation of sprouting angiogenesis |
| E | 1904749 | biological_process | regulation of protein localization to nucleolus |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MN A 401 |
| Chain | Residue |
| A | GLU136 |
| A | GLU196 |
| A | GLU203 |
| A | MN404 |
| A | PO4502 |
| A | HOH1686 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MN A 402 |
| Chain | Residue |
| A | ARG340 |
| A | ADP501 |
| A | PO4502 |
| A | GLU134 |
| A | HIS253 |
| A | GLU338 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MN A 403 |
| Chain | Residue |
| A | GLU134 |
| A | GLU203 |
| A | ADP501 |
| A | PO4502 |
| A | HOH1635 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MN A 404 |
| Chain | Residue |
| A | GLU196 |
| A | MN401 |
| A | PO4502 |
| A | HOH1729 |
| A | HOH1730 |
| A | HOH1731 |
| site_id | AC5 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE PO4 A 502 |
| Chain | Residue |
| A | GLU134 |
| A | GLU136 |
| A | GLU196 |
| A | GLU203 |
| A | HIS253 |
| A | ARG319 |
| A | GLU338 |
| A | ARG340 |
| A | MN401 |
| A | MN402 |
| A | MN403 |
| A | MN404 |
| A | ADP501 |
| A | HOH1686 |
| A | HOH1730 |
| A | HOH1786 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MN B 401 |
| Chain | Residue |
| B | GLU136 |
| B | GLU196 |
| B | GLU203 |
| B | MN404 |
| B | PO4502 |
| B | HOH1747 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MN B 402 |
| Chain | Residue |
| B | GLU134 |
| B | HIS253 |
| B | GLU338 |
| B | ARG340 |
| B | ADP501 |
| B | PO4502 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MN B 403 |
| Chain | Residue |
| B | GLU134 |
| B | GLU203 |
| B | ADP501 |
| B | PO4502 |
| B | HOH1616 |
| site_id | AC9 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE MN B 404 |
| Chain | Residue |
| B | GLU196 |
| B | MN401 |
| B | PO4502 |
| B | HOH1730 |
| B | HOH1738 |
| B | HOH1739 |
| B | HOH1740 |
| site_id | BC1 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE PO4 B 502 |
| Chain | Residue |
| B | GLU134 |
| B | GLU136 |
| B | GLU196 |
| B | GLU203 |
| B | HIS253 |
| B | ARG319 |
| B | GLU338 |
| B | ARG340 |
| B | MN401 |
| B | MN402 |
| B | MN403 |
| B | MN404 |
| B | ADP501 |
| B | HOH1616 |
| B | HOH1740 |
| site_id | BC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MN C 401 |
| Chain | Residue |
| C | GLU136 |
| C | GLU196 |
| C | GLU203 |
| C | MN404 |
| C | PO4502 |
| C | HOH1745 |
| site_id | BC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MN C 402 |
| Chain | Residue |
| C | GLU134 |
| C | HIS253 |
| C | GLU338 |
| C | ARG340 |
| C | ADP501 |
| C | PO4502 |
| site_id | BC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MN C 403 |
| Chain | Residue |
| C | GLU134 |
| C | GLU203 |
| C | ADP501 |
| C | PO4502 |
| C | HOH1604 |
| site_id | BC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MN C 404 |
| Chain | Residue |
| C | HOH1718 |
| C | HOH1719 |
| B | HOH1741 |
| C | GLU196 |
| C | MN401 |
| C | PO4502 |
| site_id | BC6 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE PO4 C 502 |
| Chain | Residue |
| B | HOH1741 |
| C | GLU134 |
| C | GLU136 |
| C | GLU196 |
| C | GLU203 |
| C | HIS253 |
| C | ARG319 |
| C | GLU338 |
| C | ARG340 |
| C | MN401 |
| C | MN402 |
| C | MN403 |
| C | MN404 |
| C | ADP501 |
| C | HOH1707 |
| C | HOH1718 |
| C | HOH1745 |
| site_id | BC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MN D 401 |
| Chain | Residue |
| D | GLU136 |
| D | GLU196 |
| D | GLU203 |
| D | MN404 |
| D | PO4502 |
| D | HOH1741 |
| site_id | BC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MN D 402 |
| Chain | Residue |
| D | GLU134 |
| D | HIS253 |
| D | GLU338 |
| D | ARG340 |
| D | ADP501 |
| D | PO4502 |
| site_id | BC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MN D 403 |
| Chain | Residue |
| D | GLU134 |
| D | GLU203 |
| D | ADP501 |
| D | PO4502 |
| D | HOH1615 |
| site_id | CC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MN D 404 |
| Chain | Residue |
| D | GLU196 |
| D | MN401 |
| D | PO4502 |
| D | HOH1609 |
| D | HOH1739 |
| D | HOH1740 |
| site_id | CC2 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE PO4 D 502 |
| Chain | Residue |
| D | GLU134 |
| D | GLU136 |
| D | GLU196 |
| D | GLU203 |
| D | HIS253 |
| D | ARG319 |
| D | GLU338 |
| D | ARG340 |
| D | MN401 |
| D | MN402 |
| D | MN403 |
| D | MN404 |
| D | ADP501 |
| D | HOH1598 |
| D | HOH1739 |
| D | HOH1740 |
| D | HOH1741 |
| site_id | CC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MN E 401 |
| Chain | Residue |
| E | GLU136 |
| E | GLU196 |
| E | GLU203 |
| E | MN404 |
| E | PO4502 |
| E | HOH1666 |
| site_id | CC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MN E 402 |
| Chain | Residue |
| E | GLU134 |
| E | HIS253 |
| E | GLU338 |
| E | ARG340 |
| E | ADP501 |
| E | PO4502 |
| site_id | CC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MN E 403 |
| Chain | Residue |
| E | GLU134 |
| E | GLU203 |
| E | ADP501 |
| E | PO4502 |
| E | HOH1609 |
| site_id | CC6 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE MN E 404 |
| Chain | Residue |
| E | GLU136 |
| E | GLU196 |
| E | MN401 |
| E | PO4502 |
| E | HOH1611 |
| E | HOH1716 |
| E | HOH1717 |
| site_id | CC7 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE PO4 E 502 |
| Chain | Residue |
| E | GLU134 |
| E | GLU136 |
| E | GLU196 |
| E | GLU203 |
| E | HIS253 |
| E | ARG319 |
| E | GLU338 |
| E | ARG340 |
| E | MN401 |
| E | MN402 |
| E | MN403 |
| E | MN404 |
| E | ADP501 |
| E | HOH1699 |
| E | HOH1716 |
| site_id | CC8 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL B 1401 |
| Chain | Residue |
| B | THR44 |
| C | THR193 |
| site_id | CC9 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL C 1402 |
| Chain | Residue |
| C | MET29 |
| C | THR44 |
| D | THR193 |
| site_id | DC1 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL A 1403 |
| Chain | Residue |
| A | THR193 |
| E | THR44 |
| site_id | DC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL D 1404 |
| Chain | Residue |
| D | THR44 |
| E | THR193 |
| E | HOH1531 |
| site_id | DC3 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL A 1405 |
| Chain | Residue |
| A | THR44 |
| B | THR193 |
| site_id | DC4 |
| Number of Residues | 23 |
| Details | BINDING SITE FOR RESIDUE ADP A 501 |
| Chain | Residue |
| A | TRP130 |
| A | GLY132 |
| A | GLU134 |
| A | GLU203 |
| A | GLN205 |
| A | GLY207 |
| A | PRO208 |
| A | ASN255 |
| A | SER257 |
| A | ARG319 |
| A | ARG324 |
| A | TYR336 |
| A | GLU338 |
| A | MN402 |
| A | MN403 |
| A | PO4502 |
| A | HOH1540 |
| A | HOH1587 |
| A | HOH1619 |
| A | HOH1620 |
| A | HOH1635 |
| A | HOH1664 |
| E | HOH1513 |
| site_id | DC5 |
| Number of Residues | 23 |
| Details | BINDING SITE FOR RESIDUE ADP B 501 |
| Chain | Residue |
| A | HOH1575 |
| B | TRP130 |
| B | GLY132 |
| B | GLU134 |
| B | GLU203 |
| B | GLN205 |
| B | GLY207 |
| B | PRO208 |
| B | ASN255 |
| B | SER257 |
| B | ARG319 |
| B | ARG324 |
| B | TYR336 |
| B | GLU338 |
| B | MN402 |
| B | MN403 |
| B | PO4502 |
| B | HOH1560 |
| B | HOH1570 |
| B | HOH1589 |
| B | HOH1616 |
| B | HOH1693 |
| B | HOH1753 |
| site_id | DC6 |
| Number of Residues | 23 |
| Details | BINDING SITE FOR RESIDUE ADP C 501 |
| Chain | Residue |
| C | TRP130 |
| C | GLY132 |
| C | GLU134 |
| C | GLU203 |
| C | GLN205 |
| C | GLY207 |
| C | PRO208 |
| C | ASN255 |
| C | SER257 |
| C | ARG319 |
| C | ARG324 |
| C | TYR336 |
| C | GLU338 |
| C | MN402 |
| C | MN403 |
| C | PO4502 |
| C | HOH1584 |
| C | HOH1600 |
| C | HOH1603 |
| C | HOH1604 |
| C | HOH1656 |
| C | HOH1674 |
| C | HOH1681 |
| site_id | DC7 |
| Number of Residues | 24 |
| Details | BINDING SITE FOR RESIDUE ADP D 501 |
| Chain | Residue |
| D | TRP130 |
| D | GLY132 |
| D | GLU134 |
| D | GLU203 |
| D | GLN205 |
| D | GLY207 |
| D | PRO208 |
| D | ASN255 |
| D | SER257 |
| D | ARG319 |
| D | ARG324 |
| D | TYR336 |
| D | GLU338 |
| D | MN402 |
| D | MN403 |
| D | PO4502 |
| D | HOH1585 |
| D | HOH1597 |
| D | HOH1615 |
| D | HOH1628 |
| D | HOH1631 |
| D | HOH1636 |
| D | HOH1716 |
| D | HOH1750 |
| site_id | DC8 |
| Number of Residues | 23 |
| Details | BINDING SITE FOR RESIDUE ADP E 501 |
| Chain | Residue |
| D | HOH1617 |
| E | TRP130 |
| E | GLY132 |
| E | GLU134 |
| E | GLU203 |
| E | GLN205 |
| E | GLY207 |
| E | PRO208 |
| E | ASN255 |
| E | SER257 |
| E | ARG262 |
| E | ARG319 |
| E | ARG324 |
| E | TYR336 |
| E | GLU338 |
| E | MN402 |
| E | MN403 |
| E | PO4502 |
| E | HOH1540 |
| E | HOH1555 |
| E | HOH1609 |
| E | HOH1636 |
| E | HOH1644 |
| site_id | DC9 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL A 1501 |
| Chain | Residue |
| A | LYS14 |
| A | PRO88 |
| A | PHE89 |
| A | HOH1543 |
| A | HOH1665 |
| A | HOH1694 |
| site_id | EC1 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL B 1502 |
| Chain | Residue |
| A | TYR17 |
| B | LYS14 |
| B | PRO88 |
| B | PHE89 |
| B | HOH1548 |
| B | HOH1674 |
| B | HOH1748 |
| B | HOH1756 |
| site_id | EC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL C 1503 |
| Chain | Residue |
| C | LYS14 |
| C | PRO88 |
| C | PHE89 |
| C | HOH1557 |
| C | HOH1734 |
| site_id | EC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL D 1504 |
| Chain | Residue |
| D | LYS14 |
| D | PRO88 |
| D | PHE89 |
| D | HOH1601 |
| D | HOH1752 |
| site_id | EC4 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL E 1505 |
| Chain | Residue |
| D | VAL16 |
| E | LYS14 |
| E | PRO88 |
| E | PHE89 |
| E | HOH1557 |
| E | HOH1594 |
| E | HOH1642 |
| site_id | EC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL C 1506 |
| Chain | Residue |
| C | ALA82 |
| C | SER213 |
| C | ASP216 |
| C | HIS217 |
| C | HOH1781 |
Functional Information from PROSITE/UniProt
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 410 |
| Details | Domain: {"description":"GS beta-grasp","evidences":[{"source":"PROSITE-ProRule","id":"PRU01330","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 30 |
| Details | Binding site: {"evidences":[{"source":"PDB","id":"2QC8","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 50 |
| Details | Binding site: {"evidences":[{"source":"PDB","id":"2OJW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2QC8","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 15 |
| Details | Binding site: {"evidences":[{"source":"UniProtKB","id":"P9WN39","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 10 |
| Details | Modified residue: {"description":"N6-acetyllysine; by EP300","evidences":[{"source":"PubMed","id":"26990986","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 5 |
| Details | Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"UniProtKB","id":"P15105","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 5 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"24275569","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1hto |
| Chain | Residue | Details |
| A | ARG319 | |
| A | ASP63 |
| site_id | CSA2 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1hto |
| Chain | Residue | Details |
| B | ARG319 | |
| B | ASP63 |
| site_id | CSA3 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1hto |
| Chain | Residue | Details |
| C | ARG319 | |
| C | ASP63 |
| site_id | CSA4 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1hto |
| Chain | Residue | Details |
| D | ARG319 | |
| D | ASP63 |
| site_id | CSA5 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1hto |
| Chain | Residue | Details |
| E | ARG319 | |
| E | ASP63 |
