2OHG

Structural Basis for Glutamte Racemase Inhibition

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0008360	biological_process	regulation of cell shape
A	0008881	molecular_function	glutamate racemase activity
A	0009252	biological_process	peptidoglycan biosynthetic process
A	0016853	molecular_function	isomerase activity
A	0016855	molecular_function	racemase and epimerase activity, acting on amino acids and derivatives
A	0036361	molecular_function	racemase activity, acting on amino acids and derivatives
A	0071555	biological_process	cell wall organization

Functional Information from PROSITE/UniProt

site_id	PS00924
Number of Residues	11
Details	ASP_GLU_RACEMASE_2 Aspartate and glutamate racemases signature 2. LVlGCTHYPlL

Chain	Residue	Details
A	LEU179-LEU189

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	ACT_SITE: Proton donor/acceptor => ECO:0000250|UniProtKB:O58403, ECO:0000255|HAMAP-Rule:MF_00258

Chain	Residue	Details
A	CYS73
A	CYS183

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site_id	SWS_FT_FI2
Number of Residues	2
Details	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00258, ECO:0000305|PubMed:17658548

Chain	Residue	Details
A	ASP10
A	ASN74

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site_id	SWS_FT_FI3
Number of Residues	2
Details	BINDING: BINDING => ECO:0000250|UniProtKB:P22634, ECO:0000255|HAMAP-Rule:MF_00258

Chain	Residue	Details
A	TYR42
A	THR184

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Catalytic Information from CSA

site_id	CSA1
Number of Residues	4
Details	Annotated By Reference To The Literature 1b73

Chain	Residue	Details
A	ASP10
A	CYS183
A	CYS73
A	SER11

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