2OGE
x-ray structure of S. venezuelae DesV in its internal aldimine form
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000271 | biological_process | polysaccharide biosynthetic process |
| A | 0008483 | molecular_function | transaminase activity |
| A | 0009058 | biological_process | biosynthetic process |
| A | 0016740 | molecular_function | transferase activity |
| A | 0017000 | biological_process | antibiotic biosynthetic process |
| A | 0030170 | molecular_function | pyridoxal phosphate binding |
| A | 0033068 | biological_process | macrolide biosynthetic process |
| B | 0000271 | biological_process | polysaccharide biosynthetic process |
| B | 0008483 | molecular_function | transaminase activity |
| B | 0009058 | biological_process | biosynthetic process |
| B | 0016740 | molecular_function | transferase activity |
| B | 0017000 | biological_process | antibiotic biosynthetic process |
| B | 0030170 | molecular_function | pyridoxal phosphate binding |
| B | 0033068 | biological_process | macrolide biosynthetic process |
| C | 0000271 | biological_process | polysaccharide biosynthetic process |
| C | 0008483 | molecular_function | transaminase activity |
| C | 0009058 | biological_process | biosynthetic process |
| C | 0016740 | molecular_function | transferase activity |
| C | 0017000 | biological_process | antibiotic biosynthetic process |
| C | 0030170 | molecular_function | pyridoxal phosphate binding |
| C | 0033068 | biological_process | macrolide biosynthetic process |
| D | 0000271 | biological_process | polysaccharide biosynthetic process |
| D | 0008483 | molecular_function | transaminase activity |
| D | 0009058 | biological_process | biosynthetic process |
| D | 0016740 | molecular_function | transferase activity |
| D | 0017000 | biological_process | antibiotic biosynthetic process |
| D | 0030170 | molecular_function | pyridoxal phosphate binding |
| D | 0033068 | biological_process | macrolide biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL A 1297 |
| Chain | Residue |
| A | TYR39 |
| A | LEU40 |
| A | HOH1482 |
| B | HOH1450 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL A 1298 |
| Chain | Residue |
| A | TYR227 |
| A | HIS229 |
| A | EDO1304 |
| B | HOH1313 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NA A 1299 |
| Chain | Residue |
| A | HOH1338 |
| B | ASN65 |
| B | HOH1308 |
| B | HOH1309 |
| B | HOH1454 |
| A | ASN65 |
| site_id | AC4 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL B 1300 |
| Chain | Residue |
| B | TYR39 |
| B | LEU40 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL B 1301 |
| Chain | Residue |
| A | TYR318 |
| A | HOH1435 |
| B | HIS229 |
| B | EDO1304 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL C 1302 |
| Chain | Residue |
| C | TYR39 |
| C | LEU40 |
| C | HOH1343 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL C 1303 |
| Chain | Residue |
| C | TYR227 |
| C | HIS229 |
| C | EDO1309 |
| C | HOH1533 |
| D | TYR318 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NA C 1304 |
| Chain | Residue |
| C | ASN65 |
| C | HOH1361 |
| C | HOH1528 |
| D | ASN65 |
| D | HOH1476 |
| D | HOH1477 |
| site_id | AC9 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL D 1305 |
| Chain | Residue |
| D | TYR39 |
| D | LEU40 |
| site_id | BC1 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL D 1306 |
| Chain | Residue |
| C | TYR318 |
| D | HIS229 |
| site_id | BC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO A 1300 |
| Chain | Residue |
| A | PRO11 |
| A | PHE12 |
| A | LEU13 |
| A | ASP14 |
| A | ASP313 |
| A | HOH1309 |
| site_id | BC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO A 1301 |
| Chain | Residue |
| A | TYR55 |
| A | GLU57 |
| A | ARG172 |
| A | ARG177 |
| site_id | BC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO A 1302 |
| Chain | Residue |
| A | THR118 |
| A | PRO121 |
| A | ASP146 |
| A | HOH1361 |
| A | HOH1364 |
| A | HOH1529 |
| site_id | BC5 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE EDO A 1303 |
| Chain | Residue |
| A | PRO191 |
| A | LLP193 |
| A | ASN194 |
| A | GLY196 |
| A | ARG249 |
| A | HOH1313 |
| A | HOH1388 |
| A | HOH1389 |
| site_id | BC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO A 1304 |
| Chain | Residue |
| A | TYR227 |
| A | HIS229 |
| A | CL1298 |
| B | TYR93 |
| site_id | BC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO B 1302 |
| Chain | Residue |
| B | PRO11 |
| B | PHE12 |
| B | LEU13 |
| B | ASP313 |
| B | HOH1331 |
| site_id | BC8 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE EDO B 1303 |
| Chain | Residue |
| B | PRO191 |
| B | LLP193 |
| B | ASN194 |
| B | ARG249 |
| B | PRO355 |
| B | HOH1332 |
| B | HOH1410 |
| B | HOH1412 |
| site_id | BC9 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO A 1305 |
| Chain | Residue |
| A | TYR93 |
| A | TYR190 |
| A | LLP193 |
| B | TYR221 |
| B | ASN235 |
| B | ARG237 |
| site_id | CC1 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE EDO C 1305 |
| Chain | Residue |
| C | PHE12 |
| C | LEU13 |
| C | GLY192 |
| C | HIS291 |
| C | LEU292 |
| C | HOH1320 |
| C | HOH1322 |
| C | HOH1410 |
| site_id | CC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO C 1306 |
| Chain | Residue |
| C | ARG151 |
| C | ARG176 |
| C | ARG177 |
| C | HOH1404 |
| C | HOH1521 |
| site_id | CC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO D 1307 |
| Chain | Residue |
| D | PHE12 |
| D | LEU13 |
| D | ASP313 |
| D | HOH1486 |
| D | HOH1582 |
| D | PRO11 |
| site_id | CC4 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE EDO D 1308 |
| Chain | Residue |
| D | PRO191 |
| D | LLP193 |
| D | ASN194 |
| D | ARG249 |
| D | PRO355 |
| D | HOH1337 |
| D | HOH1419 |
| D | HOH1422 |
| site_id | CC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO C 1307 |
| Chain | Residue |
| C | ASP27 |
| C | EDO1308 |
| D | ASP27 |
| site_id | CC6 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO D 1309 |
| Chain | Residue |
| D | HIS113 |
| D | HIS116 |
| D | THR118 |
| D | ASP146 |
| D | HOH1392 |
| D | HOH1393 |
| D | HOH1403 |
| site_id | CC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO A 1306 |
| Chain | Residue |
| A | ASP27 |
| A | ALA31 |
| B | ASP27 |
| B | ILE30 |
| site_id | CC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO B 1304 |
| Chain | Residue |
| A | LEU315 |
| A | HIS317 |
| B | LYS226 |
| B | TYR227 |
| B | CL1301 |
| B | HOH1451 |
| site_id | CC9 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE EDO D 1310 |
| Chain | Residue |
| C | GLY37 |
| D | LEU13 |
| D | ASP14 |
| D | LEU15 |
| D | LYS16 |
| D | HOH1318 |
| D | HOH1336 |
| D | HOH1486 |
| site_id | DC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO D 1311 |
| Chain | Residue |
| D | ARG172 |
| D | ARG177 |
| D | HOH1534 |
| site_id | DC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO C 1308 |
| Chain | Residue |
| C | ASP27 |
| C | ALA28 |
| C | EDO1307 |
| C | HOH1337 |
| site_id | DC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO C 1309 |
| Chain | Residue |
| C | LYS226 |
| C | TYR227 |
| C | CL1303 |
| C | HOH1534 |
| D | HIS317 |
| site_id | DC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO D 1312 |
| Chain | Residue |
| D | TYR93 |
| D | GLN167 |
| D | LLP193 |
| D | TYR318 |
| D | HOH1386 |
| D | HOH1611 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 28 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:17456741 |
| Chain | Residue | Details |
| A | GLY67 | |
| B | SER188 | |
| B | TYR221 | |
| B | TYR227 | |
| B | ASN235 | |
| B | TYR318 | |
| C | GLY67 | |
| C | GLN167 | |
| C | SER188 | |
| C | TYR221 | |
| C | TYR227 | |
| A | GLN167 | |
| C | ASN235 | |
| C | TYR318 | |
| D | GLY67 | |
| D | GLN167 | |
| D | SER188 | |
| D | TYR221 | |
| D | TYR227 | |
| D | ASN235 | |
| D | TYR318 | |
| A | SER188 | |
| A | TYR221 | |
| A | TYR227 | |
| A | ASN235 | |
| A | TYR318 | |
| B | GLY67 | |
| B | GLN167 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | MOD_RES: N6-(pyridoxal phosphate)lysine => ECO:0000305|PubMed:17456741 |
| Chain | Residue | Details |
| A | LLP193 | |
| B | LLP193 | |
| C | LLP193 | |
| D | LLP193 |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1ay4 |
| Chain | Residue | Details |
| A | ASP164 | |
| A | TYR93 | |
| B | ARG38 |
| site_id | CSA2 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1ay4 |
| Chain | Residue | Details |
| A | ARG38 | |
| B | ASP164 | |
| B | TYR93 |
| site_id | CSA3 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1ay4 |
| Chain | Residue | Details |
| D | ARG38 | |
| C | ASP164 | |
| C | TYR93 |
| site_id | CSA4 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1ay4 |
| Chain | Residue | Details |
| C | ARG38 | |
| D | ASP164 | |
| D | TYR93 |
