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2OGD

T. Brucei Farnesyl Diphosphate Synthase Complexed with Bisphosphonate BPH-527

Functional Information from GO Data
ChainGOidnamespacecontents
A0004659molecular_functionprenyltransferase activity
A0008299biological_processisoprenoid biosynthetic process
A0016740molecular_functiontransferase activity
A0016765molecular_functiontransferase activity, transferring alkyl or aryl (other than methyl) groups
A0046872molecular_functionmetal ion binding
B0004659molecular_functionprenyltransferase activity
B0008299biological_processisoprenoid biosynthetic process
B0016740molecular_functiontransferase activity
B0016765molecular_functiontransferase activity, transferring alkyl or aryl (other than methyl) groups
B0046872molecular_functionmetal ion binding
Functional Information from PROSITE/UniProt
site_idPS00444
Number of Residues13
DetailsPOLYPRENYL_SYNTHASE_2 Polyprenyl synthases signature 2. MGeyFQVqDDVmD
ChainResidueDetails
AMET247-ASP259

site_idPS00723
Number of Residues15
DetailsPOLYPRENYL_SYNTHASE_1 Polyprenyl synthases signature 1. LVeDDim..DnsvtRRG
ChainResidueDetails
ALEU100-GLY114

Catalytic Information from CSA
site_idCSA1
Number of Residues2
DetailsAnnotated By Reference To The Literature 1fps
ChainResidueDetails
APHE251
AARG112

site_idCSA2
Number of Residues2
DetailsAnnotated By Reference To The Literature 1fps
ChainResidueDetails
BPHE251
BARG112

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PDB entries from 2024-07-17

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