2O8X
Crystal structure of the "-35 element" promoter recognition domain of Mycobacterium tuberculosis SigC
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003677 | molecular_function | DNA binding |
| A | 0003700 | molecular_function | DNA-binding transcription factor activity |
| A | 0006352 | biological_process | DNA-templated transcription initiation |
| A | 0006355 | biological_process | regulation of DNA-templated transcription |
| A | 0016987 | molecular_function | sigma factor activity |
| B | 0003677 | molecular_function | DNA binding |
| B | 0003700 | molecular_function | DNA-binding transcription factor activity |
| B | 0006352 | biological_process | DNA-templated transcription initiation |
| B | 0006355 | biological_process | regulation of DNA-templated transcription |
| B | 0016987 | molecular_function | sigma factor activity |
| C | 0003677 | molecular_function | DNA binding |
| C | 0003700 | molecular_function | DNA-binding transcription factor activity |
| C | 0006352 | biological_process | DNA-templated transcription initiation |
| C | 0006355 | biological_process | regulation of DNA-templated transcription |
| C | 0016987 | molecular_function | sigma factor activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 A 101 |
| Chain | Residue |
| A | THR132 |
| A | THR133 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 B 102 |
| Chain | Residue |
| A | LEU140 |
| B | VAL124 |
| B | LEU174 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 B 103 |
| Chain | Residue |
| B | LEU140 |
| B | LEU141 |
| B | LEU145 |
| C | VAL124 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 C 104 |
| Chain | Residue |
| A | VAL124 |
| A | LEU175 |
| C | LEU140 |
| C | LEU141 |
| C | LEU145 |
| site_id | AC5 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 A 105 |
| Chain | Residue |
| A | TYR149 |
| A | ARG171 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 B 106 |
| Chain | Residue |
| B | HOH16 |
| B | THR132 |
| B | ASP134 |
| B | GLN135 |
| B | ARG169 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 C 107 |
| Chain | Residue |
| C | THR132 |
| C | ASP134 |
| C | GLN135 |
| C | ARG169 |
| site_id | AC8 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 A 108 |
| Chain | Residue |
| A | THR162 |
| A | ARG166 |
| site_id | AC9 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 B 109 |
| Chain | Residue |
| B | THR132 |
| B | THR133 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 57 |
| Details | DNA binding: {"description":"H-T-H motif","evidences":[{"evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 153 |
| Details | Region: {"description":"Sigma-70 factor domain-4"} |
| Chain | Residue | Details |
