Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0003855 | molecular_function | 3-dehydroquinate dehydratase activity |
A | 0004764 | molecular_function | shikimate 3-dehydrogenase (NADP+) activity |
A | 0019632 | biological_process | shikimate metabolic process |
A | 0050661 | molecular_function | NADP binding |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE SO4 A 1403 |
Chain | Residue |
A | TRP158 |
A | PRO527 |
A | HOH9243 |
site_id | AC2 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE SO4 A 1402 |
Chain | Residue |
A | ASN483 |
A | ARG484 |
A | THR485 |
site_id | AC3 |
Number of Residues | 8 |
Details | BINDING SITE FOR RESIDUE SO4 A 1401 |
Chain | Residue |
A | LYS385 |
A | GLU386 |
A | GLY462 |
A | GLY463 |
A | HOH9320 |
A | ILE382 |
A | PRO383 |
A | HIS384 |
site_id | AC4 |
Number of Residues | 12 |
Details | BINDING SITE FOR RESIDUE DHK A 9241 |
Chain | Residue |
A | GLU124 |
A | ARG126 |
A | ARG155 |
A | HIS214 |
A | LYS241 |
A | LEU269 |
A | ARG279 |
A | PHE291 |
A | SER300 |
A | ALA301 |
A | GLN304 |
A | HOH9259 |
site_id | AC5 |
Number of Residues | 12 |
Details | BINDING SITE FOR RESIDUE DHK A 4733 |
Chain | Residue |
A | ILE328 |
A | SER336 |
A | SER338 |
A | SER379 |
A | THR381 |
A | LYS385 |
A | ASN406 |
A | ASP423 |
A | TYR550 |
A | GLN578 |
A | GLN582 |
A | HOH9388 |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 1 |
Details | ACT_SITE: Proton acceptor; for 3-dehydroquinate dehydratase activity => ECO:0000305|PubMed:16784230 |
Chain | Residue | Details |
A | HIS214 | |
site_id | SWS_FT_FI2 |
Number of Residues | 1 |
Details | ACT_SITE: Schiff-base intermediate with substrate; for 3-dehydroquinate dehydratase activity => ECO:0000305|PubMed:16784230 |
Chain | Residue | Details |
A | LYS241 | |
Chain | Residue | Details |
A | LYS385 | |
A | ASP423 | |
Chain | Residue | Details |
A | GLU124 | |
A | ARG126 | |
A | ARG155 | |
A | LYS241 | |
A | ARG279 | |
A | SER300 | |
A | GLN304 | |
Chain | Residue | Details |
A | SER336 | |
A | SER338 | |
A | THR381 | |
A | LYS385 | |
A | ASN406 | |
A | ASP423 | |
A | TYR550 | |
A | GLN578 | |
A | GLN582 | |
Chain | Residue | Details |
A | ALA461 | |
A | GLY463 | |
A | ALA464 | |
A | ASN483 | |
A | THR485 | |
A | ARG488 | |
A | MET525 | |
A | ALA548 | |
A | GLY571 | |
Catalytic Information from CSA
site_id | CSA1 |
Number of Residues | 3 |
Details | Annotated By Reference To The Literature 1qfe |
Chain | Residue | Details |
A | LYS241 | |
A | HIS214 | |
A | GLU159 | |
site_id | CSA2 |
Number of Residues | 1 |
Details | Annotated By Reference To The Literature 1qfe |
Chain | Residue | Details |
A | ASP414 | |