2NY7
HIV-1 gp120 Envelope Glycoprotein Complexed with the Broadly Neutralizing CD4-Binding-Site Antibody b12
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| G | 0019031 | cellular_component | viral envelope |
| L | 0002250 | biological_process | adaptive immune response |
| L | 0003823 | molecular_function | antigen binding |
| L | 0005576 | cellular_component | extracellular region |
| L | 0005615 | cellular_component | extracellular space |
| L | 0005886 | cellular_component | plasma membrane |
| L | 0006955 | biological_process | immune response |
| L | 0016064 | biological_process | immunoglobulin mediated immune response |
| L | 0019814 | cellular_component | immunoglobulin complex |
| L | 0050853 | biological_process | B cell receptor signaling pathway |
| L | 0070062 | cellular_component | extracellular exosome |
| L | 0071735 | cellular_component | IgG immunoglobulin complex |
| L | 0071738 | cellular_component | IgD immunoglobulin complex |
| L | 0071742 | cellular_component | IgE immunoglobulin complex |
| L | 0071745 | cellular_component | IgA immunoglobulin complex |
| L | 0071753 | cellular_component | IgM immunoglobulin complex |
| L | 0072562 | cellular_component | blood microparticle |
Functional Information from PROSITE/UniProt
| site_id | PS00290 |
| Number of Residues | 7 |
| Details | IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YACEVTH |
| Chain | Residue | Details |
| L | TYR192-HIS198 | |
| H | TYR206-HIS212 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 6 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine; by host => ECO:0000255|HAMAP-Rule:MF_04083 |
| Chain | Residue | Details |
| G | PHE93 | |
| G | ILE201 | |
| G | PRO212 | |
| G | ILE272 | |
| G | ASN397 | |
| G | ASN406 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 5 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine; by host => ECO:0000255|HAMAP-Rule:MF_04083, ECO:0000269|PubMed:11188697, ECO:0000269|PubMed:14981267, ECO:0000269|PubMed:26972002, ECO:0000269|PubMed:9641677 |
| Chain | Residue | Details |
| G | MET104 | |
| G | CYS247 | |
| G | ALA266 | |
| G | ASN392 | |
| G | ASN448 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine; by host => ECO:0000255|HAMAP-Rule:MF_04083, ECO:0000269|PubMed:11188697, ECO:0000269|PubMed:14981267, ECO:0000269|PubMed:26972002 |
| Chain | Residue | Details |
| G | CYS205 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine; by host => ECO:0000255|HAMAP-Rule:MF_04083, ECO:0000269|PubMed:11188697, ECO:0000269|PubMed:14981267, ECO:0000269|PubMed:23539181, ECO:0000269|PubMed:26972002, ECO:0000269|PubMed:9641677 |
| Chain | Residue | Details |
| G | PHE233 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine; by host => ECO:0000255|HAMAP-Rule:MF_04083, ECO:0000269|PubMed:11188697, ECO:0000269|PubMed:14981267, ECO:0000269|PubMed:9641677 |
| Chain | Residue | Details |
| G | LEU260 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 1 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine; by host => ECO:0000255|HAMAP-Rule:MF_04083, ECO:0000269|PubMed:21998254, ECO:0000269|PubMed:26972002, ECO:0000269|PubMed:9641677 |
| Chain | Residue | Details |
| G | ASN332 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 2 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine; by host => ECO:0000255|HAMAP-Rule:MF_04083, ECO:0000269|PubMed:11188697, ECO:0000269|PubMed:26972002, ECO:0000269|PubMed:9641677 |
| Chain | Residue | Details |
| G | ASN339 | |
| G | ASN386 |
| site_id | SWS_FT_FI8 |
| Number of Residues | 1 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine; by host => ECO:0000255|HAMAP-Rule:MF_04083, ECO:0000269|PubMed:17301785, ECO:0000269|PubMed:19965434, ECO:0007744|PDB:2NY7, ECO:0007744|PDB:3IDX, ECO:0007744|PDB:3IDY |
| Chain | Residue | Details |
| G | ASN356 |
| site_id | SWS_FT_FI9 |
| Number of Residues | 1 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine; by host => ECO:0000255|HAMAP-Rule:MF_04083, ECO:0000269|PubMed:11188697, ECO:0000269|PubMed:14981267 |
| Chain | Residue | Details |
| G | ASN463 |
