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2NV5

Crystal structure of a C-terminal phosphatase domain of Rattus norvegicus ortholog of human protein tyrosine phosphatase, receptor type, D (PTPRD)

Functional Information from GO Data
ChainGOidnamespacecontents
A0004725molecular_functionprotein tyrosine phosphatase activity
A0006470biological_processprotein dephosphorylation
A0016311biological_processdephosphorylation
B0004725molecular_functionprotein tyrosine phosphatase activity
B0006470biological_processprotein dephosphorylation
B0016311biological_processdephosphorylation
C0004725molecular_functionprotein tyrosine phosphatase activity
C0006470biological_processprotein dephosphorylation
C0016311biological_processdephosphorylation
Functional Information from PROSITE/UniProt
site_idPS00383
Number of Residues11
DetailsTYR_PHOSPHATASE_1 Tyrosine specific protein phosphatases active site. VHCsaGvgRTG
ChainResidueDetails
AVAL1422-GLY1432

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues3
DetailsACT_SITE: Phosphocysteine intermediate => ECO:0000250
ChainResidueDetails
ACYS1424
BCYS1424
CCYS1424

site_idSWS_FT_FI2
Number of Residues9
DetailsBINDING: BINDING => ECO:0000250
ChainResidueDetails
AASP1392
ACYS1424
AGLN1468
BASP1392
BCYS1424
BGLN1468
CASP1392
CCYS1424
CGLN1468

Catalytic Information from CSA
site_idCSA1
Number of Residues6
DetailsAnnotated By Reference To The Literature 1ytw
ChainResidueDetails
AASP1392
AARG1430
AGLU1330
ACYS1424
AHIS1423
ATHR1431

site_idCSA2
Number of Residues6
DetailsAnnotated By Reference To The Literature 1ytw
ChainResidueDetails
BASP1392
BARG1430
BGLU1330
BCYS1424
BHIS1423
BTHR1431

site_idCSA3
Number of Residues6
DetailsAnnotated By Reference To The Literature 1ytw
ChainResidueDetails
CASP1392
CARG1430
CGLU1330
CCYS1424
CHIS1423
CTHR1431

site_idCSA4
Number of Residues4
DetailsAnnotated By Reference To The Literature 1ytw
ChainResidueDetails
AARG1430
AASP1392
ACYS1424
ATHR1431

site_idCSA5
Number of Residues4
DetailsAnnotated By Reference To The Literature 1ytw
ChainResidueDetails
BARG1430
BASP1392
BCYS1424
BTHR1431

site_idCSA6
Number of Residues4
DetailsAnnotated By Reference To The Literature 1ytw
ChainResidueDetails
CARG1430
CASP1392
CCYS1424
CTHR1431

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PDB entries from 2024-05-01

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