2NUE

Crystal structure of RNase III from Aquifex aeolicus complexed with ds-RNA at 2.9-Angstrom Resolution

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003723	molecular_function	RNA binding
A	0003725	molecular_function	double-stranded RNA binding
A	0004519	molecular_function	endonuclease activity
A	0004525	molecular_function	ribonuclease III activity
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0006364	biological_process	rRNA processing
A	0006396	biological_process	RNA processing
A	0006397	biological_process	mRNA processing
A	0008033	biological_process	tRNA processing
A	0010468	biological_process	regulation of gene expression
A	0042802	molecular_function	identical protein binding
A	0046872	molecular_function	metal ion binding
B	0003723	molecular_function	RNA binding
B	0003725	molecular_function	double-stranded RNA binding
B	0004519	molecular_function	endonuclease activity
B	0004525	molecular_function	ribonuclease III activity
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0006364	biological_process	rRNA processing
B	0006396	biological_process	RNA processing
B	0006397	biological_process	mRNA processing
B	0008033	biological_process	tRNA processing
B	0010468	biological_process	regulation of gene expression
B	0042802	molecular_function	identical protein binding
B	0046872	molecular_function	metal ion binding

Functional Information from PROSITE/UniProt

site_id	PS00517
Number of Residues	9
Details	RNASE_3_1 Ribonuclease III family signature. ETLEFLGDA

Chain	Residue	Details
A	GLU37-ALA45

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI3
Number of Residues	6
Details	BINDING: BINDING => ECO:0000269\|PubMed:15016361, ECO:0000269\|PubMed:18047582, ECO:0000305\|PubMed:11738048, ECO:0007744\|PDB:1JFZ, ECO:0007744\|PDB:1RC5