2NMV

Damage detection by the UvrABC pathway: Crystal structure of UvrB bound to fluorescein-adducted DNA

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0000715	biological_process	nucleotide-excision repair, DNA damage recognition
A	0003677	molecular_function	DNA binding
A	0004518	molecular_function	nuclease activity
A	0005524	molecular_function	ATP binding
A	0005737	cellular_component	cytoplasm
A	0006281	biological_process	DNA repair
A	0006289	biological_process	nucleotide-excision repair
A	0006974	biological_process	DNA damage response
A	0009380	cellular_component	excinuclease repair complex
A	0009381	molecular_function	excinuclease ABC activity
A	0009432	biological_process	SOS response
A	0016787	molecular_function	hydrolase activity
A	0016887	molecular_function	ATP hydrolysis activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	13
Details	BINDING SITE FOR RESIDUE ADP A 662

Chain	Residue
A	TYR11
A	THR46
A	PHE47
A	PRO414
A	ARG543
A	GLN12
A	GLN14
A	GLN17
A	ALA40
A	GLY42
A	THR43
A	GLY44
A	LYS45

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site_id	AC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE NML D 103

Chain	Residue
D	DT2
D	DT3

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site_id	AC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE FLU D 600

Chain	Residue
A	GLY71
A	TYR74
A	SER75
A	ASN116
A	ILE119

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	387
Details	Domain: {"description":"Helicase ATP-binding","evidences":[{"source":"HAMAP-Rule","id":"MF_00204","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	23
Details	Motif: {"description":"Beta-hairpin"}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	7
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00204","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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