Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004379 | molecular_function | glycylpeptide N-tetradecanoyltransferase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0006499 | biological_process | N-terminal protein myristoylation |
| A | 0016740 | molecular_function | transferase activity |
| A | 0016746 | molecular_function | acyltransferase activity |
| A | 0018008 | biological_process | N-terminal peptidyl-glycine N-myristoylation |
| A | 0072657 | biological_process | protein localization to membrane |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 29 |
| Details | BINDING SITE FOR RESIDUE NHM A 500 |
| Chain | Residue |
| A | HIS38 |
| A | PHE170 |
| A | LEU171 |
| A | CYS172 |
| A | VAL173 |
| A | ARG178 |
| A | SER179 |
| A | ARG181 |
| A | LEU182 |
| A | THR183 |
| A | PRO184 |
| A | LYS39 |
| A | ILE187 |
| A | THR191 |
| A | TRP200 |
| A | HIS201 |
| A | ALA202 |
| A | TYR204 |
| A | THR205 |
| A | PHE425 |
| A | MIM700 |
| A | HOH1003 |
| A | PHE40 |
| A | TRP41 |
| A | ASN102 |
| A | TYR103 |
| A | VAL104 |
| A | ILE168 |
| A | ASN169 |
| site_id | AC2 |
| Number of Residues | 20 |
| Details | BINDING SITE FOR RESIDUE MIM A 700 |
| Chain | Residue |
| A | VAL104 |
| A | ASP106 |
| A | ASP108 |
| A | PHE113 |
| A | TYR115 |
| A | ASN169 |
| A | THR205 |
| A | GLY207 |
| A | TYR219 |
| A | HIS221 |
| A | PRO223 |
| A | PHE234 |
| A | THR235 |
| A | PHE334 |
| A | GLY416 |
| A | ASP417 |
| A | GLY418 |
| A | LEU455 |
| A | NHM500 |
| A | HOH1016 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL A 801 |
| Chain | Residue |
| A | MET246 |
| A | GLU249 |
| A | GOL812 |
| A | HOH1034 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE GOL A 802 |
| Chain | Residue |
| A | ASP132 |
| A | ASP245 |
| A | GOL809 |
| site_id | AC5 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE GOL A 803 |
| Chain | Residue |
| A | CYS197 |
| A | GOL809 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE GOL A 804 |
| Chain | Residue |
| A | HIS296 |
| A | HOH1043 |
| A | HOH1055 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL A 805 |
| Chain | Residue |
| A | LYS263 |
| A | PHE298 |
| A | GLY300 |
| A | ILE311 |
| A | SER313 |
| site_id | AC8 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE GOL A 806 |
| Chain | Residue |
| A | ASP270 |
| A | LYS291 |
| A | ASP307 |
| site_id | AC9 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE GOL A 807 |
| Chain | Residue |
| A | PRO58 |
| A | HIS201 |
| site_id | BC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL A 808 |
| Chain | Residue |
| A | GLU80 |
| A | TRP81 |
| A | CYS82 |
| A | SER83 |
| A | GLN91 |
| A | ARG138 |
| site_id | BC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL A 809 |
| Chain | Residue |
| A | ASP132 |
| A | THR242 |
| A | GLU244 |
| A | ASP245 |
| A | GOL802 |
| A | GOL803 |
| site_id | BC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL A 810 |
| Chain | Residue |
| A | GLU317 |
| A | PRO319 |
| A | ASP320 |
| A | GLY321 |
| site_id | BC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL A 811 |
| Chain | Residue |
| A | ASP70 |
| A | ASP70 |
| A | LYS196 |
| A | GLU244 |
| site_id | BC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL A 812 |
| Chain | Residue |
| A | ASP85 |
| A | HIS241 |
| A | GLU249 |
| A | GOL801 |
| A | HOH1034 |
Functional Information from PROSITE/UniProt
| site_id | PS00975 |
| Number of Residues | 9 |
| Details | NMT_1 Myristoyl-CoA:protein N-myristoyltransferase signature 1. EINFLCvHK |
| Chain | Residue | Details |
| A | GLU167-LYS175 | |
| site_id | PS00976 |
| Number of Residues | 7 |
| Details | NMT_2 Myristoyl-CoA:protein N-myristoyltransferase signature 2. KFGpGDG |
| Chain | Residue | Details |
| A | LYS412-GLY418 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 36 |
| Details | Region: {"description":"Myristoyl CoA-binding"} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Proton acceptor; via carboxylate","evidences":[{"source":"PubMed","id":"11478885","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 3 |
| Details | Binding site: {} |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 4 |
| Details | a catalytic site defined by CSA, PubMed 9846880, 10570244, 11371195, 11478885, 11527981 |
| Chain | Residue | Details |
| A | PHE170 | |
| A | LEU455 | |
| A | ASN169 | |
| A | LEU171 | |
| site_id | MCSA1 |
| Number of Residues | 5 |
| Details | M-CSA 928 |
| Chain | Residue | Details |
| A | ASN169 | electrostatic stabiliser |
| A | PHE170 | electrostatic stabiliser |
| A | LEU171 | electrostatic stabiliser |
| A | THR205 | electrostatic stabiliser |
| A | LEU455 | proton shuttle (general acid/base) |
