2NLO

Crystal Structure of the Quinate Dehydrogenase from Corynebacterium glutamicum

Replaces:  2EZ3

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004764	molecular_function	shikimate 3-dehydrogenase (NADP+) activity
A	0005829	cellular_component	cytosol
A	0008652	biological_process	amino acid biosynthetic process
A	0009073	biological_process	aromatic amino acid family biosynthetic process
A	0009423	biological_process	chorismate biosynthetic process
A	0016491	molecular_function	oxidoreductase activity
A	0019632	biological_process	shikimate metabolic process
A	0030266	molecular_function	quinate 3-dehydrogenase (NAD+) activity
A	0050661	molecular_function	NADP binding
A	0052734	molecular_function	shikimate 3-dehydrogenase (NAD+) activity
A	0070403	molecular_function	NAD+ binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	10
Details	BINDING SITE FOR RESIDUE GOL A 9991

Chain	Residue
A	ASN86
A	HOH506
A	ILE87
A	THR88
A	LYS92
A	ASN113
A	ASP129
A	VAL157
A	GLN277
A	HOH355

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Functional Information from PROSITE/UniProt

site_id	PS00962
Number of Residues	12
Details	RIBOSOMAL_S2_1 Ribosomal protein S2 signature 1. LkTLLDAALYLG

Chain	Residue	Details
A	LEU70-GLY81

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	ACT_SITE: Proton acceptor => ECO:0000255|HAMAP-Rule:MF_00222, ECO:0000269|PubMed:23929881

Chain	Residue	Details
A	LYS92

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site_id	SWS_FT_FI2
Number of Residues	6
Details	BINDING: BINDING => ECO:0000269|PubMed:23929881, ECO:0007744|PDB:3JYQ

Chain	Residue	Details
A	SER36
A	THR88
A	LYS92
A	ASN113
A	ASP129
A	GLN277

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site_id	SWS_FT_FI3
Number of Residues	3
Details	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00222, ECO:0000269|PubMed:23929881, ECO:0007744|PDB:3JYO, ECO:0007744|PDB:3JYP, ECO:0007744|PDB:3JYQ

Chain	Residue	Details
A	GLY156
A	VAL247
A	GLY270

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site_id	SWS_FT_FI4
Number of Residues	3
Details	BINDING: BINDING => ECO:0000269|PubMed:23929881, ECO:0007744|PDB:3JYO, ECO:0007744|PDB:3JYP, ECO:0007744|PDB:3JYQ

Chain	Residue	Details
A	ASP177
A	ARG182
A	PRO222

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site_id	SWS_FT_FI5
Number of Residues	1
Details	BINDING: BINDING => ECO:0000269|PubMed:23929881, ECO:0007744|PDB:3JYP, ECO:0007744|PDB:3JYQ

Chain	Residue	Details
A	ALA232

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Catalytic Information from CSA

site_id	CSA1
Number of Residues	1
Details	Annotated By Reference To The Literature 1nvt

Chain	Residue	Details
A	THR120

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