2NCK

CRYSTAL STRUCTURE OF MYXOCOCCUS XANTHUS NUCLEOSIDE DIPHOSPHATE KINASE AND ITS INTERACTION WITH A NUCLEOTIDE SUBSTRATE AT 2.0 ANGSTROMS RESOLUTION

Functional Information from GO Data

Chain	GOid	namespace	contents
L	0000166	molecular_function	nucleotide binding
L	0004550	molecular_function	nucleoside diphosphate kinase activity
L	0005524	molecular_function	ATP binding
L	0005737	cellular_component	cytoplasm
L	0006183	biological_process	GTP biosynthetic process
L	0006228	biological_process	UTP biosynthetic process
L	0006241	biological_process	CTP biosynthetic process
L	0009117	biological_process	nucleotide metabolic process
L	0016301	molecular_function	kinase activity
L	0016740	molecular_function	transferase activity
L	0046872	molecular_function	metal ion binding
R	0000166	molecular_function	nucleotide binding
R	0004550	molecular_function	nucleoside diphosphate kinase activity
R	0005524	molecular_function	ATP binding
R	0005737	cellular_component	cytoplasm
R	0006183	biological_process	GTP biosynthetic process
R	0006228	biological_process	UTP biosynthetic process
R	0006241	biological_process	CTP biosynthetic process
R	0009117	biological_process	nucleotide metabolic process
R	0016301	molecular_function	kinase activity
R	0016740	molecular_function	transferase activity
R	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	EPL
Number of Residues	1
Details	THE CATALYTIC HIS 117 THAT IS PHOSPHORYLATED IN THE PHOSPHOENZYME INTERMEDIATE OF THE ENZYMATIC REACTION.

Chain	Residue
L	HIS117

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site_id	EPR
Number of Residues	1
Details	THE CATALYTIC HIS 117 THAT IS PHOSPHORYLATED IN THE PHOSPHOENZYME INTERMEDIATE OF THE ENZYMATIC REACTION.

Chain	Residue
R	HIS117

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Functional Information from PROSITE/UniProt

site_id	PS00469
Number of Residues	9
Details	NDPK Nucleoside diphosphate kinase (NDPK) active site signature. NtvHGSDSL

Chain	Residue	Details
R	ASN114-LEU122

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	Active site: {"description":"Pros-phosphohistidine intermediate","evidences":[{"source":"HAMAP-Rule","id":"MF_00451","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	12
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00451","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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Catalytic Information from CSA

site_id	CSA1
Number of Residues	2
Details	Annotated By Reference To The Literature 1nsp

Chain	Residue	Details
R	ASN114
R	LYS11

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site_id	CSA2
Number of Residues	2
Details	Annotated By Reference To The Literature 1nsp

Chain	Residue	Details
L	ASN114
L	LYS11

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site_id	CSA3
Number of Residues	2
Details	Annotated By Reference To The Literature 1nsp

Chain	Residue	Details
R	TYR51
R	LYS11

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site_id	CSA4
Number of Residues	2
Details	Annotated By Reference To The Literature 1nsp

Chain	Residue	Details
L	TYR51
L	LYS11

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