2MS7

High-resolution solid-state NMR structure of the helical signal transduction filament MAVS CARD

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005739	cellular_component	mitochondrion
A	0051607	biological_process	defense response to virus
B	0005739	cellular_component	mitochondrion
B	0051607	biological_process	defense response to virus
C	0005739	cellular_component	mitochondrion
C	0051607	biological_process	defense response to virus
D	0005739	cellular_component	mitochondrion
D	0051607	biological_process	defense response to virus
E	0005739	cellular_component	mitochondrion
E	0051607	biological_process	defense response to virus
F	0005739	cellular_component	mitochondrion
F	0051607	biological_process	defense response to virus
G	0005739	cellular_component	mitochondrion
G	0051607	biological_process	defense response to virus
H	0005739	cellular_component	mitochondrion
H	0051607	biological_process	defense response to virus
I	0005739	cellular_component	mitochondrion
I	0051607	biological_process	defense response to virus
J	0005739	cellular_component	mitochondrion
J	0051607	biological_process	defense response to virus
K	0005739	cellular_component	mitochondrion
K	0051607	biological_process	defense response to virus
L	0005739	cellular_component	mitochondrion
L	0051607	biological_process	defense response to virus
M	0005739	cellular_component	mitochondrion
M	0051607	biological_process	defense response to virus
N	0005739	cellular_component	mitochondrion
N	0051607	biological_process	defense response to virus
O	0005739	cellular_component	mitochondrion
O	0051607	biological_process	defense response to virus
P	0005739	cellular_component	mitochondrion
P	0051607	biological_process	defense response to virus
Q	0005739	cellular_component	mitochondrion
Q	0051607	biological_process	defense response to virus
R	0005739	cellular_component	mitochondrion
R	0051607	biological_process	defense response to virus
S	0005739	cellular_component	mitochondrion
S	0051607	biological_process	defense response to virus
T	0005739	cellular_component	mitochondrion
T	0051607	biological_process	defense response to virus
U	0005739	cellular_component	mitochondrion
U	0051607	biological_process	defense response to virus

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1407
Details	Domain: {"description":"CARD"}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	1407
Details	Region: {"description":"Required for interaction with NLRX1","evidences":[{"source":"PubMed","id":"18200010","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	21
Details	Modified residue: {"description":"N-acetylproline","evidences":[{"source":"PubMed","id":"37316325","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	21
Details	Lipidation: {"description":"S-palmitoyl cysteine","evidences":[{"source":"PubMed","id":"38016475","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	21
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)","evidences":[{"source":"PubMed","id":"26246171","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	42
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)","evidences":[{"source":"PubMed","id":"27992402","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---