Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005634 | cellular_component | nucleus |
| A | 0043066 | biological_process | negative regulation of apoptotic process |
| A | 0051726 | biological_process | regulation of cell cycle |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE 13Q A 201 |
| Chain | Residue |
| A | VAL14 |
| A | THR16 |
| A | LEU54 |
| A | GLY58 |
| A | ILE61 |
| A | TYR67 |
| A | LYS94 |
| A | HIS96 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 83 |
| Details | Domain: {"description":"SWIB/MDM2","evidences":[{"source":"PROSITE-ProRule","id":"PRU01273","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 109 |
| Details | Region: {"description":"Necessary for interaction with USP2"} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 100 |
| Details | Region: {"description":"Sufficient to promote the mitochondrial pathway of apoptosis","evidences":[{"source":"PubMed","id":"30879903","evidenceCode":"ECO:0000269"}]} |
