Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

2KYV

Hybrid solution and solid-state NMR structure ensemble of phospholamban pentamer

Functional Information from GO Data
ChainGOidnamespacecontents
A0001675biological_processacrosome assembly
A0002026biological_processregulation of the force of heart contraction
A0004857molecular_functionenzyme inhibitor activity
A0005515molecular_functionprotein binding
A0005739cellular_componentmitochondrion
A0005783cellular_componentendoplasmic reticulum
A0005789cellular_componentendoplasmic reticulum membrane
A0006874biological_processintracellular calcium ion homeostasis
A0007219biological_processNotch signaling pathway
A0007283biological_processspermatogenesis
A0008016biological_processregulation of heart contraction
A0008542biological_processvisual learning
A0010459biological_processnegative regulation of heart rate
A0010880biological_processregulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
A0010881biological_processregulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion
A0016020cellular_componentmembrane
A0016529cellular_componentsarcoplasmic reticulum
A0031966cellular_componentmitochondrial membrane
A0033017cellular_componentsarcoplasmic reticulum membrane
A0042030molecular_functionATPase inhibitor activity
A0042802molecular_functionidentical protein binding
A0042803molecular_functionprotein homodimerization activity
A0043086biological_processnegative regulation of catalytic activity
A0045475biological_processlocomotor rhythm
A0045822biological_processnegative regulation of heart contraction
A0046716biological_processmuscle cell cellular homeostasis
A0048471cellular_componentperinuclear region of cytoplasm
A0048738biological_processcardiac muscle tissue development
A0050802biological_processcircadian sleep/wake cycle, sleep
A0051117molecular_functionATPase binding
A0051924biological_processregulation of calcium ion transport
A0051926biological_processnegative regulation of calcium ion transport
A0086004biological_processregulation of cardiac muscle cell contraction
A0086023biological_processadenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process
A0086092biological_processregulation of the force of heart contraction by cardiac conduction
A0090279biological_processregulation of calcium ion import
A0090281biological_processnegative regulation of calcium ion import
A0090534cellular_componentcalcium ion-transporting ATPase complex
A1901020biological_processnegative regulation of calcium ion transmembrane transporter activity
A1901077biological_processregulation of relaxation of muscle
A1901877biological_processnegative regulation of calcium ion binding
A1901895biological_processnegative regulation of ATPase-coupled calcium transmembrane transporter activity
A1902081biological_processnegative regulation of calcium ion import into sarcoplasmic reticulum
B0001675biological_processacrosome assembly
B0002026biological_processregulation of the force of heart contraction
B0004857molecular_functionenzyme inhibitor activity
B0005515molecular_functionprotein binding
B0005739cellular_componentmitochondrion
B0005783cellular_componentendoplasmic reticulum
B0005789cellular_componentendoplasmic reticulum membrane
B0006874biological_processintracellular calcium ion homeostasis
B0007219biological_processNotch signaling pathway
B0007283biological_processspermatogenesis
B0008016biological_processregulation of heart contraction
B0008542biological_processvisual learning
B0010459biological_processnegative regulation of heart rate
B0010880biological_processregulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
B0010881biological_processregulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion
B0016020cellular_componentmembrane
B0016529cellular_componentsarcoplasmic reticulum
B0031966cellular_componentmitochondrial membrane
B0033017cellular_componentsarcoplasmic reticulum membrane
B0042030molecular_functionATPase inhibitor activity
B0042802molecular_functionidentical protein binding
B0042803molecular_functionprotein homodimerization activity
B0043086biological_processnegative regulation of catalytic activity
B0045475biological_processlocomotor rhythm
B0045822biological_processnegative regulation of heart contraction
B0046716biological_processmuscle cell cellular homeostasis
B0048471cellular_componentperinuclear region of cytoplasm
B0048738biological_processcardiac muscle tissue development
B0050802biological_processcircadian sleep/wake cycle, sleep
B0051117molecular_functionATPase binding
B0051924biological_processregulation of calcium ion transport
B0051926biological_processnegative regulation of calcium ion transport
B0086004biological_processregulation of cardiac muscle cell contraction
B0086023biological_processadenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process
B0086092biological_processregulation of the force of heart contraction by cardiac conduction
B0090279biological_processregulation of calcium ion import
B0090281biological_processnegative regulation of calcium ion import
B0090534cellular_componentcalcium ion-transporting ATPase complex
B1901020biological_processnegative regulation of calcium ion transmembrane transporter activity
B1901077biological_processregulation of relaxation of muscle
B1901877biological_processnegative regulation of calcium ion binding
B1901895biological_processnegative regulation of ATPase-coupled calcium transmembrane transporter activity
B1902081biological_processnegative regulation of calcium ion import into sarcoplasmic reticulum
C0001675biological_processacrosome assembly
C0002026biological_processregulation of the force of heart contraction
C0004857molecular_functionenzyme inhibitor activity
C0005515molecular_functionprotein binding
C0005739cellular_componentmitochondrion
C0005783cellular_componentendoplasmic reticulum
C0005789cellular_componentendoplasmic reticulum membrane
C0006874biological_processintracellular calcium ion homeostasis
C0007219biological_processNotch signaling pathway
C0007283biological_processspermatogenesis
C0008016biological_processregulation of heart contraction
C0008542biological_processvisual learning
C0010459biological_processnegative regulation of heart rate
C0010880biological_processregulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
C0010881biological_processregulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion
C0016020cellular_componentmembrane
C0016529cellular_componentsarcoplasmic reticulum
C0031966cellular_componentmitochondrial membrane
C0033017cellular_componentsarcoplasmic reticulum membrane
C0042030molecular_functionATPase inhibitor activity
C0042802molecular_functionidentical protein binding
C0042803molecular_functionprotein homodimerization activity
C0043086biological_processnegative regulation of catalytic activity
C0045475biological_processlocomotor rhythm
C0045822biological_processnegative regulation of heart contraction
C0046716biological_processmuscle cell cellular homeostasis
C0048471cellular_componentperinuclear region of cytoplasm
C0048738biological_processcardiac muscle tissue development
C0050802biological_processcircadian sleep/wake cycle, sleep
C0051117molecular_functionATPase binding
C0051924biological_processregulation of calcium ion transport
C0051926biological_processnegative regulation of calcium ion transport
C0086004biological_processregulation of cardiac muscle cell contraction
C0086023biological_processadenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process
C0086092biological_processregulation of the force of heart contraction by cardiac conduction
C0090279biological_processregulation of calcium ion import
C0090281biological_processnegative regulation of calcium ion import
C0090534cellular_componentcalcium ion-transporting ATPase complex
C1901020biological_processnegative regulation of calcium ion transmembrane transporter activity
C1901077biological_processregulation of relaxation of muscle
C1901877biological_processnegative regulation of calcium ion binding
C1901895biological_processnegative regulation of ATPase-coupled calcium transmembrane transporter activity
C1902081biological_processnegative regulation of calcium ion import into sarcoplasmic reticulum
D0001675biological_processacrosome assembly
D0002026biological_processregulation of the force of heart contraction
D0004857molecular_functionenzyme inhibitor activity
D0005515molecular_functionprotein binding
D0005739cellular_componentmitochondrion
D0005783cellular_componentendoplasmic reticulum
D0005789cellular_componentendoplasmic reticulum membrane
D0006874biological_processintracellular calcium ion homeostasis
D0007219biological_processNotch signaling pathway
D0007283biological_processspermatogenesis
D0008016biological_processregulation of heart contraction
D0008542biological_processvisual learning
D0010459biological_processnegative regulation of heart rate
D0010880biological_processregulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
D0010881biological_processregulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion
D0016020cellular_componentmembrane
D0016529cellular_componentsarcoplasmic reticulum
D0031966cellular_componentmitochondrial membrane
D0033017cellular_componentsarcoplasmic reticulum membrane
D0042030molecular_functionATPase inhibitor activity
D0042802molecular_functionidentical protein binding
D0042803molecular_functionprotein homodimerization activity
D0043086biological_processnegative regulation of catalytic activity
D0045475biological_processlocomotor rhythm
D0045822biological_processnegative regulation of heart contraction
D0046716biological_processmuscle cell cellular homeostasis
D0048471cellular_componentperinuclear region of cytoplasm
D0048738biological_processcardiac muscle tissue development
D0050802biological_processcircadian sleep/wake cycle, sleep
D0051117molecular_functionATPase binding
D0051924biological_processregulation of calcium ion transport
D0051926biological_processnegative regulation of calcium ion transport
D0086004biological_processregulation of cardiac muscle cell contraction
D0086023biological_processadenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process
D0086092biological_processregulation of the force of heart contraction by cardiac conduction
D0090279biological_processregulation of calcium ion import
D0090281biological_processnegative regulation of calcium ion import
D0090534cellular_componentcalcium ion-transporting ATPase complex
D1901020biological_processnegative regulation of calcium ion transmembrane transporter activity
D1901077biological_processregulation of relaxation of muscle
D1901877biological_processnegative regulation of calcium ion binding
D1901895biological_processnegative regulation of ATPase-coupled calcium transmembrane transporter activity
D1902081biological_processnegative regulation of calcium ion import into sarcoplasmic reticulum
E0001675biological_processacrosome assembly
E0002026biological_processregulation of the force of heart contraction
E0004857molecular_functionenzyme inhibitor activity
E0005515molecular_functionprotein binding
E0005739cellular_componentmitochondrion
E0005783cellular_componentendoplasmic reticulum
E0005789cellular_componentendoplasmic reticulum membrane
E0006874biological_processintracellular calcium ion homeostasis
E0007219biological_processNotch signaling pathway
E0007283biological_processspermatogenesis
E0008016biological_processregulation of heart contraction
E0008542biological_processvisual learning
E0010459biological_processnegative regulation of heart rate
E0010880biological_processregulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
E0010881biological_processregulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion
E0016020cellular_componentmembrane
E0016529cellular_componentsarcoplasmic reticulum
E0031966cellular_componentmitochondrial membrane
E0033017cellular_componentsarcoplasmic reticulum membrane
E0042030molecular_functionATPase inhibitor activity
E0042802molecular_functionidentical protein binding
E0042803molecular_functionprotein homodimerization activity
E0043086biological_processnegative regulation of catalytic activity
E0045475biological_processlocomotor rhythm
E0045822biological_processnegative regulation of heart contraction
E0046716biological_processmuscle cell cellular homeostasis
E0048471cellular_componentperinuclear region of cytoplasm
E0048738biological_processcardiac muscle tissue development
E0050802biological_processcircadian sleep/wake cycle, sleep
E0051117molecular_functionATPase binding
E0051924biological_processregulation of calcium ion transport
E0051926biological_processnegative regulation of calcium ion transport
E0086004biological_processregulation of cardiac muscle cell contraction
E0086023biological_processadenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process
E0086092biological_processregulation of the force of heart contraction by cardiac conduction
E0090279biological_processregulation of calcium ion import
E0090281biological_processnegative regulation of calcium ion import
E0090534cellular_componentcalcium ion-transporting ATPase complex
E1901020biological_processnegative regulation of calcium ion transmembrane transporter activity
E1901077biological_processregulation of relaxation of muscle
E1901877biological_processnegative regulation of calcium ion binding
E1901895biological_processnegative regulation of ATPase-coupled calcium transmembrane transporter activity
E1902081biological_processnegative regulation of calcium ion import into sarcoplasmic reticulum
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues150
DetailsTOPO_DOM: Cytoplasmic => ECO:0000255
ChainResidueDetails
AMET1-LEU31
BMET1-LEU31
CMET1-LEU31
DMET1-LEU31
EMET1-LEU31

site_idSWS_FT_FI2
Number of Residues100
DetailsTRANSMEM: Helical => ECO:0000255
ChainResidueDetails
APHE32-LEU52
BPHE32-LEU52
CPHE32-LEU52
DPHE32-LEU52
EPHE32-LEU52

site_idSWS_FT_FI3
Number of Residues5
DetailsMOD_RES: N-acetylmethionine => ECO:0000250|UniProtKB:A4IFH6
ChainResidueDetails
AMET1
BMET1
CMET1
DMET1
EMET1

site_idSWS_FT_FI4
Number of Residues5
DetailsMOD_RES: Phosphoserine; by PKA and DMPK => ECO:0000250|UniProtKB:P61012
ChainResidueDetails
ASER16
BSER16
CSER16
DSER16
ESER16

site_idSWS_FT_FI5
Number of Residues5
DetailsMOD_RES: Phosphothreonine; by CaMK2 => ECO:0000250|UniProtKB:P61012
ChainResidueDetails
ATHR17
BTHR17
CTHR17
DTHR17
ETHR17

site_idSWS_FT_FI6
Number of Residues5
DetailsLIPID: S-palmitoyl cysteine => ECO:0000250|UniProtKB:P61014
ChainResidueDetails
ACYS36
BCYS36
CCYS36
DCYS36
ECYS36

227111

PDB entries from 2024-11-06

PDB statisticsPDBj update infoContact PDBjnumon