2KNI

High-resolution solution structure of the ASIC1a blocker PcTX1

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005515	molecular_function	protein binding
A	0005576	cellular_component	extracellular region
A	0035821	biological_process	modulation of process of another organism
A	0090729	molecular_function	toxin activity
A	0099106	molecular_function	ion channel regulator activity

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	3
Details	SITE: Key residue for interaction with ASIC1a => ECO:0000269|PubMed:22760635, ECO:0000269|PubMed:22842900, ECO:0000269|PubMed:26248594

Chain	Residue	Details
A	TRP8
A	ARG29
A	PHE31

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site_id	SWS_FT_FI2
Number of Residues	3
Details	SITE: Key residue for interaction with ASIC1a => ECO:0000269|PubMed:21825095, ECO:0000269|PubMed:22760635, ECO:0000269|PubMed:22842900

Chain	Residue	Details
A	TRP25
A	ARG27
A	ARG28

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