2JP3

Solution Structure of the human FXYD4 (CHIF) protein in SDS micelles

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005267	molecular_function	potassium channel activity
A	0005515	molecular_function	protein binding
A	0005886	cellular_component	plasma membrane
A	0005890	cellular_component	sodium:potassium-exchanging ATPase complex
A	0006813	biological_process	potassium ion transport
A	0006814	biological_process	sodium ion transport
A	0016020	cellular_component	membrane
A	0016323	cellular_component	basolateral plasma membrane
A	0017080	molecular_function	sodium channel regulator activity
A	0043269	biological_process	regulation of monoatomic ion transport
A	0051117	molecular_function	ATPase binding
A	0071805	biological_process	potassium ion transmembrane transport
A	0098662	biological_process	inorganic cation transmembrane transport
A	0099106	molecular_function	ion channel regulator activity
A	1903278	biological_process	positive regulation of sodium ion export across plasma membrane

Functional Information from PROSITE/UniProt

site_id	PS01310
Number of Residues	14
Details	FXYD FXYD family signature. SpFyYDweSLQlgG

Chain	Residue	Details
A	SER8-GLY21

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	14
Details	TOPO_DOM: Extracellular => ECO:0000255

Chain	Residue	Details
A	ASN1-GLU15

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site_id	SWS_FT_FI2
Number of Residues	21
Details	TRANSMEM: Helical => ECO:0000269|PubMed:17567018, ECO:0000312|PDB:2JP3

Chain	Residue	Details
A	SER16-LEU37

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site_id	SWS_FT_FI3
Number of Residues	29
Details	TOPO_DOM: Cytoplasmic => ECO:0000255

Chain	Residue	Details
A	SER38-THR67

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