2JP3
Solution Structure of the human FXYD4 (CHIF) protein in SDS micelles
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005267 | molecular_function | potassium channel activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0005890 | cellular_component | sodium:potassium-exchanging ATPase complex |
| A | 0006811 | biological_process | monoatomic ion transport |
| A | 0006813 | biological_process | potassium ion transport |
| A | 0006814 | biological_process | sodium ion transport |
| A | 0016020 | cellular_component | membrane |
| A | 0016323 | cellular_component | basolateral plasma membrane |
| A | 0017080 | molecular_function | sodium channel regulator activity |
| A | 0043269 | biological_process | regulation of monoatomic ion transport |
| A | 0051117 | molecular_function | ATPase binding |
| A | 0071805 | biological_process | potassium ion transmembrane transport |
| A | 0098662 | biological_process | inorganic cation transmembrane transport |
| A | 0099106 | molecular_function | ion channel regulator activity |
| A | 1903278 | biological_process | positive regulation of sodium ion export across plasma membrane |
Functional Information from PROSITE/UniProt
| site_id | PS01310 |
| Number of Residues | 14 |
| Details | FXYD FXYD family signature. SpFyYDweSLQlgG |
| Chain | Residue | Details |
| A | SER8-GLY21 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 14 |
| Details | Topological domain: {"description":"Extracellular","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 21 |
| Details | Transmembrane: {"description":"Helical","evidences":[{"source":"PubMed","id":"17567018","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2JP3","evidenceCode":"ECO:0000312"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 29 |
| Details | Topological domain: {"description":"Cytoplasmic","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 20 |
| Details | Region: {"description":"Disordered","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]} |
| Chain | Residue | Details |
