2JJE

Crystal structure of T330S mutant of Rv3290c from M. tuberculosis

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0008483	molecular_function	transaminase activity
A	0009450	biological_process	gamma-aminobutyric acid catabolic process
A	0016740	molecular_function	transferase activity
A	0017000	biological_process	antibiotic biosynthetic process
A	0030170	molecular_function	pyridoxal phosphate binding
A	0045484	molecular_function	L-lysine 6-transaminase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	15
Details	BINDING SITE FOR RESIDUE PLP A 1450

Chain	Residue
A	GLY128
A	SER330
A	HOH2182
A	HOH2183
A	HOH2184
A	HOH2185
A	HOH2186
A	ALA129
A	PHE167
A	HIS168
A	GLU238
A	ASP271
A	VAL273
A	GLN274
A	LYS300

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Functional Information from PROSITE/UniProt

site_id	PS00600
Number of Residues	38
Details	AA_TRANSFER_CLASS_3 Aminotransferases class-III pyridoxal-phosphate attachment site. LIfDEVqt.GCgLtGtawayqqldvap....DIVafGKktqVC

Chain	Residue	Details
A	LEU268-CYS305

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	3
Details	BINDING: BINDING => ECO:0000269|PubMed:16950391, ECO:0000269|PubMed:26003725, ECO:0007744|PDB:2CIN, ECO:0007744|PDB:2CJD, ECO:0007744|PDB:2CJH, ECO:0007744|PDB:2JJE, ECO:0007744|PDB:2JJG, ECO:0007744|PDB:2JJH

Chain	Residue	Details
A	GLY128
A	ALA129
A	GLN274

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site_id	SWS_FT_FI2
Number of Residues	1
Details	BINDING: BINDING => ECO:0000269|PubMed:16950391, ECO:0007744|PDB:2CJD

Chain	Residue	Details
A	ARG170

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site_id	SWS_FT_FI3
Number of Residues	1
Details	BINDING: BINDING => ECO:0000269|PubMed:16950391, ECO:0000269|PubMed:26003725, ECO:0007744|PDB:2CJH, ECO:0007744|PDB:2JJH

Chain	Residue	Details
A	ARG422

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site_id	SWS_FT_FI4
Number of Residues	1
Details	MOD_RES: N6-(pyridoxal phosphate)lysine => ECO:0000269|PubMed:16950391, ECO:0000269|PubMed:26003725, ECO:0007744|PDB:2CIN, ECO:0007744|PDB:2CJH, ECO:0007744|PDB:2JJE, ECO:0007744|PDB:2JJG, ECO:0007744|PDB:2JJH

Chain	Residue	Details
A	LYS300

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Catalytic Information from CSA

site_id	CSA1
Number of Residues	3
Details	Annotated By Reference To The Literature 1d7r

Chain	Residue	Details
A	LYS300
A	PHE167
A	ASP271

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site_id	CSA2
Number of Residues	1
Details	Annotated By Reference To The Literature 1d7r

Chain	Residue	Details
A	ASP97

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