2JGT
Low resolution structure of SPT
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004758 | molecular_function | serine C-palmitoyltransferase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006629 | biological_process | lipid metabolic process |
| A | 0006665 | biological_process | sphingolipid metabolic process |
| A | 0009058 | biological_process | biosynthetic process |
| A | 0016020 | cellular_component | membrane |
| A | 0016740 | molecular_function | transferase activity |
| A | 0016746 | molecular_function | acyltransferase activity |
| A | 0030170 | molecular_function | pyridoxal phosphate binding |
| B | 0004758 | molecular_function | serine C-palmitoyltransferase activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0006629 | biological_process | lipid metabolic process |
| B | 0006665 | biological_process | sphingolipid metabolic process |
| B | 0009058 | biological_process | biosynthetic process |
| B | 0016020 | cellular_component | membrane |
| B | 0016740 | molecular_function | transferase activity |
| B | 0016746 | molecular_function | acyltransferase activity |
| B | 0030170 | molecular_function | pyridoxal phosphate binding |
Functional Information from PROSITE/UniProt
| site_id | PS00599 |
| Number of Residues | 10 |
| Details | AA_TRANSFER_CLASS_2 Aminotransferases class-II pyridoxal-phosphate attachment site. TFSKSVGTVG |
| Chain | Residue | Details |
| A | THR262-GLY271 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 6 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"17559874","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19376777","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2JG2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2W8T","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2W8U","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2W8V","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"17559874","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2JG2","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"N6-(pyridoxal phosphate)lysine","evidences":[{"source":"PubMed","id":"17559874","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19376777","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2JG2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2W8T","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2W8U","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2W8V","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1bs0 |
| Chain | Residue | Details |
| A | ASP231 | |
| A | HIS159 |
| site_id | CSA10 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1bs0 |
| Chain | Residue | Details |
| B | HIS234 | |
| B | LYS265 |
| site_id | CSA11 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1bs0 |
| Chain | Residue | Details |
| A | ARG103 |
| site_id | CSA12 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1bs0 |
| Chain | Residue | Details |
| B | ARG103 |
| site_id | CSA2 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1bs0 |
| Chain | Residue | Details |
| B | ASN106 |
| site_id | CSA3 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1bs0 |
| Chain | Residue | Details |
| A | ASP231 | |
| A | LYS265 | |
| A | HIS159 | |
| A | GLU202 |
| site_id | CSA4 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1bs0 |
| Chain | Residue | Details |
| B | ASP231 | |
| B | LYS265 | |
| B | GLU202 |
| site_id | CSA5 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1bs0 |
| Chain | Residue | Details |
| A | ASP231 | |
| A | LYS265 | |
| A | HIS159 |
| site_id | CSA6 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1bs0 |
| Chain | Residue | Details |
| B | ASP231 | |
| B | LYS265 |
| site_id | CSA7 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1bs0 |
| Chain | Residue | Details |
| A | TYR135 | |
| A | ASP231 | |
| A | LYS265 |
| site_id | CSA8 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1bs0 |
| Chain | Residue | Details |
| B | TYR135 | |
| B | ASP231 | |
| B | LYS265 |
| site_id | CSA9 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1bs0 |
| Chain | Residue | Details |
| A | HIS234 | |
| A | LYS265 |
