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2JGA

Crystal structure of human cytosolic 5'-nucleotidase III in complex with phosphate and magnesium

Functional Information from GO Data
ChainGOidnamespacecontents
A0000287molecular_functionmagnesium ion binding
A0005737cellular_componentcytoplasm
A0008253molecular_function5'-nucleotidase activity
Functional Information from PDB Data
site_idAC1
Number of Residues8
DetailsBINDING SITE FOR RESIDUE PO4 A1287
ChainResidue
AASP38
APHE39
AASP40
ASER153
AALA154
AGLY155
ALYS202
AMG1288

site_idAC2
Number of Residues4
DetailsBINDING SITE FOR RESIDUE MG A1288
ChainResidue
AASP40
AASP227
APO41287
AASP38

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues1
DetailsACT_SITE: Nucleophile => ECO:0000269|PubMed:17405878
ChainResidueDetails
APRO88

site_idSWS_FT_FI2
Number of Residues1
DetailsACT_SITE: Proton donor => ECO:0000269|PubMed:17405878
ChainResidueDetails
ALEU90

site_idSWS_FT_FI3
Number of Residues4
DetailsBINDING: BINDING => ECO:0000269|PubMed:17405878
ChainResidueDetails
APRO88
ALEU90
AHIS203
AVAL277

site_idSWS_FT_FI4
Number of Residues2
DetailsBINDING: BINDING => ECO:0000250|UniProtKB:Q9W197
ChainResidueDetails
ATYR135
AILE156

site_idSWS_FT_FI5
Number of Residues1
DetailsBINDING: BINDING => ECO:0000250|UniProtKB:Q9D020
ChainResidueDetails
AASP252

site_idSWS_FT_FI6
Number of Residues1
DetailsMOD_RES: Phosphoserine => ECO:0000250|UniProtKB:Q9D020
ChainResidueDetails
AALA278

226707

PDB entries from 2024-10-30

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