2JFK

Structure of the MAT domain of human FAS with malonyl-CoA

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0016740	molecular_function	transferase activity
B	0016740	molecular_function	transferase activity
C	0016740	molecular_function	transferase activity
D	0016740	molecular_function	transferase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE COA A1820

Chain	Residue
A	GLY500
A	ARG676

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site_id	AC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE COA B1823

Chain	Residue
B	LYS673
B	ARG676

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site_id	AC3
Number of Residues	1
Details	BINDING SITE FOR RESIDUE COA C1824

Chain	Residue
C	ARG676

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site_id	AC4
Number of Residues	2
Details	BINDING SITE FOR RESIDUE COA D1821

Chain	Residue
D	VAL675
D	ARG676

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	Active site: {"description":"For malonyltransferase activity","evidences":[{"source":"PROSITE-ProRule","id":"PRU10022","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	12
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"P19096","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	12
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"19608861","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI4
Number of Residues	4
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"P19096","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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