Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

2JC3

Structure of O-Acetylserine Sulfhydrylase B from Salmonella Typhimurium

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004124	molecular_function	cysteine synthase activity
A	0005737	cellular_component	cytoplasm
A	0006535	biological_process	cysteine biosynthetic process from serine
A	0008652	biological_process	amino acid biosynthetic process
A	0016740	molecular_function	transferase activity
A	0016765	molecular_function	transferase activity, transferring alkyl or aryl (other than methyl) groups
A	0019344	biological_process	cysteine biosynthetic process
B	0004124	molecular_function	cysteine synthase activity
B	0005737	cellular_component	cytoplasm
B	0006535	biological_process	cysteine biosynthetic process from serine
B	0008652	biological_process	amino acid biosynthetic process
B	0016740	molecular_function	transferase activity
B	0016765	molecular_function	transferase activity, transferring alkyl or aryl (other than methyl) groups
B	0019344	biological_process	cysteine biosynthetic process
C	0004124	molecular_function	cysteine synthase activity
C	0005737	cellular_component	cytoplasm
C	0006535	biological_process	cysteine biosynthetic process from serine
C	0008652	biological_process	amino acid biosynthetic process
C	0016740	molecular_function	transferase activity
C	0016765	molecular_function	transferase activity, transferring alkyl or aryl (other than methyl) groups
C	0019344	biological_process	cysteine biosynthetic process
D	0004124	molecular_function	cysteine synthase activity
D	0005737	cellular_component	cytoplasm
D	0006535	biological_process	cysteine biosynthetic process from serine
D	0008652	biological_process	amino acid biosynthetic process
D	0016740	molecular_function	transferase activity
D	0016765	molecular_function	transferase activity, transferring alkyl or aryl (other than methyl) groups
D	0019344	biological_process	cysteine biosynthetic process
E	0004124	molecular_function	cysteine synthase activity
E	0005737	cellular_component	cytoplasm
E	0006535	biological_process	cysteine biosynthetic process from serine
E	0008652	biological_process	amino acid biosynthetic process
E	0016740	molecular_function	transferase activity
E	0016765	molecular_function	transferase activity, transferring alkyl or aryl (other than methyl) groups
E	0019344	biological_process	cysteine biosynthetic process
F	0004124	molecular_function	cysteine synthase activity
F	0005737	cellular_component	cytoplasm
F	0006535	biological_process	cysteine biosynthetic process from serine
F	0008652	biological_process	amino acid biosynthetic process
F	0016740	molecular_function	transferase activity
F	0016765	molecular_function	transferase activity, transferring alkyl or aryl (other than methyl) groups
F	0019344	biological_process	cysteine biosynthetic process
G	0004124	molecular_function	cysteine synthase activity
G	0005737	cellular_component	cytoplasm
G	0006535	biological_process	cysteine biosynthetic process from serine
G	0008652	biological_process	amino acid biosynthetic process
G	0016740	molecular_function	transferase activity
G	0016765	molecular_function	transferase activity, transferring alkyl or aryl (other than methyl) groups
G	0019344	biological_process	cysteine biosynthetic process
H	0004124	molecular_function	cysteine synthase activity
H	0005737	cellular_component	cytoplasm
H	0006535	biological_process	cysteine biosynthetic process from serine
H	0008652	biological_process	amino acid biosynthetic process
H	0016740	molecular_function	transferase activity
H	0016765	molecular_function	transferase activity, transferring alkyl or aryl (other than methyl) groups
H	0019344	biological_process	cysteine biosynthetic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	16
Details	BINDING SITE FOR RESIDUE PLP A1294

Chain	Residue
A	LYS41
A	SER255
A	CYS280
A	ASP281
A	TYR286
A	HOH2038
A	HOH2044
A	HOH2074
A	ASN71
A	SER172
A	GLY174
A	THR175
A	THR176
A	GLY177
A	THR178
A	ILE209

site_id	AC2
Number of Residues	18
Details	BINDING SITE FOR RESIDUE PLP B1294

Chain	Residue
B	LYS41
B	ASN71
B	SER172
B	GLY174
B	THR175
B	THR176
B	GLY177
B	THR178
B	GLY208
B	ILE209
B	SER255
B	CYS280
B	ASP281
B	TYR286
B	HOH2061
B	HOH2089
B	HOH2090
B	HOH2091

site_id	AC3
Number of Residues	17
Details	BINDING SITE FOR RESIDUE PLP C1294

Chain	Residue
C	LYS41
C	ASN71
C	SER172
C	GLY174
C	THR175
C	THR176
C	GLY177
C	THR178
C	GLY208
C	ILE209
C	SER255
C	CYS280
C	ASP281
C	TYR286
C	HOH2042
C	HOH2079
C	HOH2080

site_id	AC4
Number of Residues	17
Details	BINDING SITE FOR RESIDUE PLP D1294

Chain	Residue
D	LYS41
D	ASN71
D	SER172
D	GLY174
D	THR175
D	THR176
D	GLY177
D	THR178
D	GLY208
D	ILE209
D	SER255
D	CYS280
D	ASP281
D	TYR286
D	HOH2077
D	HOH2078
D	HOH2079

site_id	AC5
Number of Residues	17
Details	BINDING SITE FOR RESIDUE PLP E1294

Chain	Residue
E	LYS41
E	ASN71
E	SER172
E	GLY174
E	THR175
E	THR176
E	GLY177
E	THR178
E	GLY208
E	ILE209
E	SER255
E	CYS280
E	ASP281
E	TYR286
E	HOH2086
E	HOH2087
E	HOH2088

site_id	AC6
Number of Residues	17
Details	BINDING SITE FOR RESIDUE PLP F1294

Chain	Residue
F	HOH2075
F	HOH2076
F	HOH2077
F	LYS41
F	ASN71
F	SER172
F	GLY174
F	THR175
F	THR176
F	GLY177
F	THR178
F	GLY208
F	ILE209
F	SER255
F	CYS280
F	ASP281
F	TYR286

site_id	AC7
Number of Residues	16
Details	BINDING SITE FOR RESIDUE PLP G1294

Chain	Residue
G	LYS41
G	ASN71
G	SER172
G	MET173
G	GLY174
G	THR175
G	THR176
G	GLY177
G	THR178
G	GLY208
G	SER255
G	CYS280
G	ASP281
G	TYR286
G	HOH2022
G	HOH2045

site_id	AC8
Number of Residues	17
Details	BINDING SITE FOR RESIDUE PLP H1294

Chain	Residue
H	LYS41
H	ASN71
H	SER172
H	GLY174
H	THR175
H	THR176
H	GLY177
H	THR178
H	GLY208
H	SER255
H	CYS280
H	ASP281
H	TYR286
H	HOH2053
H	HOH2092
H	HOH2093
H	HOH2094

Functional Information from PROSITE/UniProt

site_id	PS00901
Number of Residues	19
Details	CYS_SYNTHASE Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. KlEgnn.PAgSVKdRaAlsM

Chain	Residue	Details
A	LYS30-MET48

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	48
Details	Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

site_id	SWS_FT_FI2
Number of Residues	8
Details	Modified residue: {"description":"N6-(pyridoxal phosphate)lysine","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

Catalytic Information from CSA

site_id	CSA1
Number of Residues	2
Details	Annotated By Reference To The Literature 1oas

Chain	Residue	Details
A	SER255
A	LYS41

site_id	CSA10
Number of Residues	1
Details	Annotated By Reference To The Literature 1oas

Chain	Residue	Details
B	LYS41

site_id	CSA11
Number of Residues	1
Details	Annotated By Reference To The Literature 1oas

Chain	Residue	Details
C	LYS41

site_id	CSA12
Number of Residues	1
Details	Annotated By Reference To The Literature 1oas

Chain	Residue	Details
D	LYS41

site_id	CSA13
Number of Residues	1
Details	Annotated By Reference To The Literature 1oas

Chain	Residue	Details
E	LYS41

site_id	CSA14
Number of Residues	1
Details	Annotated By Reference To The Literature 1oas

Chain	Residue	Details
F	LYS41

site_id	CSA15
Number of Residues	1
Details	Annotated By Reference To The Literature 1oas

Chain	Residue	Details
G	LYS41

site_id	CSA16
Number of Residues	1
Details	Annotated By Reference To The Literature 1oas

Chain	Residue	Details
H	LYS41

site_id	CSA2
Number of Residues	2
Details	Annotated By Reference To The Literature 1oas

Chain	Residue	Details
B	SER255
B	LYS41

site_id	CSA3
Number of Residues	2
Details	Annotated By Reference To The Literature 1oas

Chain	Residue	Details
C	SER255
C	LYS41

site_id	CSA4
Number of Residues	2
Details	Annotated By Reference To The Literature 1oas

Chain	Residue	Details
D	SER255
D	LYS41

site_id	CSA5
Number of Residues	2
Details	Annotated By Reference To The Literature 1oas

Chain	Residue	Details
E	SER255
E	LYS41

site_id	CSA6
Number of Residues	2
Details	Annotated By Reference To The Literature 1oas

Chain	Residue	Details
F	SER255
F	LYS41

site_id	CSA7
Number of Residues	2
Details	Annotated By Reference To The Literature 1oas

Chain	Residue	Details
G	SER255
G	LYS41

site_id	CSA8
Number of Residues	2
Details	Annotated By Reference To The Literature 1oas

Chain	Residue	Details
H	SER255
H	LYS41

site_id	CSA9
Number of Residues	1
Details	Annotated By Reference To The Literature 1oas

Chain	Residue	Details
A	LYS41

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)