2JC3
Structure of O-Acetylserine Sulfhydrylase B from Salmonella Typhimurium
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004124 | molecular_function | cysteine synthase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006535 | biological_process | cysteine biosynthetic process from serine |
| A | 0008652 | biological_process | amino acid biosynthetic process |
| A | 0016740 | molecular_function | transferase activity |
| A | 0016765 | molecular_function | transferase activity, transferring alkyl or aryl (other than methyl) groups |
| A | 0019344 | biological_process | cysteine biosynthetic process |
| B | 0004124 | molecular_function | cysteine synthase activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0006535 | biological_process | cysteine biosynthetic process from serine |
| B | 0008652 | biological_process | amino acid biosynthetic process |
| B | 0016740 | molecular_function | transferase activity |
| B | 0016765 | molecular_function | transferase activity, transferring alkyl or aryl (other than methyl) groups |
| B | 0019344 | biological_process | cysteine biosynthetic process |
| C | 0004124 | molecular_function | cysteine synthase activity |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0006535 | biological_process | cysteine biosynthetic process from serine |
| C | 0008652 | biological_process | amino acid biosynthetic process |
| C | 0016740 | molecular_function | transferase activity |
| C | 0016765 | molecular_function | transferase activity, transferring alkyl or aryl (other than methyl) groups |
| C | 0019344 | biological_process | cysteine biosynthetic process |
| D | 0004124 | molecular_function | cysteine synthase activity |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0006535 | biological_process | cysteine biosynthetic process from serine |
| D | 0008652 | biological_process | amino acid biosynthetic process |
| D | 0016740 | molecular_function | transferase activity |
| D | 0016765 | molecular_function | transferase activity, transferring alkyl or aryl (other than methyl) groups |
| D | 0019344 | biological_process | cysteine biosynthetic process |
| E | 0004124 | molecular_function | cysteine synthase activity |
| E | 0005737 | cellular_component | cytoplasm |
| E | 0006535 | biological_process | cysteine biosynthetic process from serine |
| E | 0008652 | biological_process | amino acid biosynthetic process |
| E | 0016740 | molecular_function | transferase activity |
| E | 0016765 | molecular_function | transferase activity, transferring alkyl or aryl (other than methyl) groups |
| E | 0019344 | biological_process | cysteine biosynthetic process |
| F | 0004124 | molecular_function | cysteine synthase activity |
| F | 0005737 | cellular_component | cytoplasm |
| F | 0006535 | biological_process | cysteine biosynthetic process from serine |
| F | 0008652 | biological_process | amino acid biosynthetic process |
| F | 0016740 | molecular_function | transferase activity |
| F | 0016765 | molecular_function | transferase activity, transferring alkyl or aryl (other than methyl) groups |
| F | 0019344 | biological_process | cysteine biosynthetic process |
| G | 0004124 | molecular_function | cysteine synthase activity |
| G | 0005737 | cellular_component | cytoplasm |
| G | 0006535 | biological_process | cysteine biosynthetic process from serine |
| G | 0008652 | biological_process | amino acid biosynthetic process |
| G | 0016740 | molecular_function | transferase activity |
| G | 0016765 | molecular_function | transferase activity, transferring alkyl or aryl (other than methyl) groups |
| G | 0019344 | biological_process | cysteine biosynthetic process |
| H | 0004124 | molecular_function | cysteine synthase activity |
| H | 0005737 | cellular_component | cytoplasm |
| H | 0006535 | biological_process | cysteine biosynthetic process from serine |
| H | 0008652 | biological_process | amino acid biosynthetic process |
| H | 0016740 | molecular_function | transferase activity |
| H | 0016765 | molecular_function | transferase activity, transferring alkyl or aryl (other than methyl) groups |
| H | 0019344 | biological_process | cysteine biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE PLP A1294 |
| Chain | Residue |
| A | LYS41 |
| A | SER255 |
| A | CYS280 |
| A | ASP281 |
| A | TYR286 |
| A | HOH2038 |
| A | HOH2044 |
| A | HOH2074 |
| A | ASN71 |
| A | SER172 |
| A | GLY174 |
| A | THR175 |
| A | THR176 |
| A | GLY177 |
| A | THR178 |
| A | ILE209 |
| site_id | AC2 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE PLP B1294 |
| Chain | Residue |
| B | LYS41 |
| B | ASN71 |
| B | SER172 |
| B | GLY174 |
| B | THR175 |
| B | THR176 |
| B | GLY177 |
| B | THR178 |
| B | GLY208 |
| B | ILE209 |
| B | SER255 |
| B | CYS280 |
| B | ASP281 |
| B | TYR286 |
| B | HOH2061 |
| B | HOH2089 |
| B | HOH2090 |
| B | HOH2091 |
| site_id | AC3 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE PLP C1294 |
| Chain | Residue |
| C | LYS41 |
| C | ASN71 |
| C | SER172 |
| C | GLY174 |
| C | THR175 |
| C | THR176 |
| C | GLY177 |
| C | THR178 |
| C | GLY208 |
| C | ILE209 |
| C | SER255 |
| C | CYS280 |
| C | ASP281 |
| C | TYR286 |
| C | HOH2042 |
| C | HOH2079 |
| C | HOH2080 |
| site_id | AC4 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE PLP D1294 |
| Chain | Residue |
| D | LYS41 |
| D | ASN71 |
| D | SER172 |
| D | GLY174 |
| D | THR175 |
| D | THR176 |
| D | GLY177 |
| D | THR178 |
| D | GLY208 |
| D | ILE209 |
| D | SER255 |
| D | CYS280 |
| D | ASP281 |
| D | TYR286 |
| D | HOH2077 |
| D | HOH2078 |
| D | HOH2079 |
| site_id | AC5 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE PLP E1294 |
| Chain | Residue |
| E | LYS41 |
| E | ASN71 |
| E | SER172 |
| E | GLY174 |
| E | THR175 |
| E | THR176 |
| E | GLY177 |
| E | THR178 |
| E | GLY208 |
| E | ILE209 |
| E | SER255 |
| E | CYS280 |
| E | ASP281 |
| E | TYR286 |
| E | HOH2086 |
| E | HOH2087 |
| E | HOH2088 |
| site_id | AC6 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE PLP F1294 |
| Chain | Residue |
| F | HOH2075 |
| F | HOH2076 |
| F | HOH2077 |
| F | LYS41 |
| F | ASN71 |
| F | SER172 |
| F | GLY174 |
| F | THR175 |
| F | THR176 |
| F | GLY177 |
| F | THR178 |
| F | GLY208 |
| F | ILE209 |
| F | SER255 |
| F | CYS280 |
| F | ASP281 |
| F | TYR286 |
| site_id | AC7 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE PLP G1294 |
| Chain | Residue |
| G | LYS41 |
| G | ASN71 |
| G | SER172 |
| G | MET173 |
| G | GLY174 |
| G | THR175 |
| G | THR176 |
| G | GLY177 |
| G | THR178 |
| G | GLY208 |
| G | SER255 |
| G | CYS280 |
| G | ASP281 |
| G | TYR286 |
| G | HOH2022 |
| G | HOH2045 |
| site_id | AC8 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE PLP H1294 |
| Chain | Residue |
| H | LYS41 |
| H | ASN71 |
| H | SER172 |
| H | GLY174 |
| H | THR175 |
| H | THR176 |
| H | GLY177 |
| H | THR178 |
| H | GLY208 |
| H | SER255 |
| H | CYS280 |
| H | ASP281 |
| H | TYR286 |
| H | HOH2053 |
| H | HOH2092 |
| H | HOH2093 |
| H | HOH2094 |
Functional Information from PROSITE/UniProt
| site_id | PS00901 |
| Number of Residues | 19 |
| Details | CYS_SYNTHASE Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. KlEgnn.PAgSVKdRaAlsM |
| Chain | Residue | Details |
| A | LYS30-MET48 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 24 |
| Details | BINDING: BINDING => ECO:0000250 |
| Chain | Residue | Details |
| A | ASN71 | |
| D | ASN71 | |
| D | GLY174 | |
| D | SER255 | |
| E | ASN71 | |
| E | GLY174 | |
| E | SER255 | |
| F | ASN71 | |
| F | GLY174 | |
| F | SER255 | |
| G | ASN71 | |
| A | GLY174 | |
| G | GLY174 | |
| G | SER255 | |
| H | ASN71 | |
| H | GLY174 | |
| H | SER255 | |
| A | SER255 | |
| B | ASN71 | |
| B | GLY174 | |
| B | SER255 | |
| C | ASN71 | |
| C | GLY174 | |
| C | SER255 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 8 |
| Details | MOD_RES: N6-(pyridoxal phosphate)lysine => ECO:0000250 |
| Chain | Residue | Details |
| A | LYS41 | |
| B | LYS41 | |
| C | LYS41 | |
| D | LYS41 | |
| E | LYS41 | |
| F | LYS41 | |
| G | LYS41 | |
| H | LYS41 |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1oas |
| Chain | Residue | Details |
| A | SER255 | |
| A | LYS41 |
| site_id | CSA10 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1oas |
| Chain | Residue | Details |
| B | LYS41 |
| site_id | CSA11 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1oas |
| Chain | Residue | Details |
| C | LYS41 |
| site_id | CSA12 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1oas |
| Chain | Residue | Details |
| D | LYS41 |
| site_id | CSA13 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1oas |
| Chain | Residue | Details |
| E | LYS41 |
| site_id | CSA14 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1oas |
| Chain | Residue | Details |
| F | LYS41 |
| site_id | CSA15 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1oas |
| Chain | Residue | Details |
| G | LYS41 |
| site_id | CSA16 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1oas |
| Chain | Residue | Details |
| H | LYS41 |
| site_id | CSA2 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1oas |
| Chain | Residue | Details |
| B | SER255 | |
| B | LYS41 |
| site_id | CSA3 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1oas |
| Chain | Residue | Details |
| C | SER255 | |
| C | LYS41 |
| site_id | CSA4 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1oas |
| Chain | Residue | Details |
| D | SER255 | |
| D | LYS41 |
| site_id | CSA5 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1oas |
| Chain | Residue | Details |
| E | SER255 | |
| E | LYS41 |
| site_id | CSA6 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1oas |
| Chain | Residue | Details |
| F | SER255 | |
| F | LYS41 |
| site_id | CSA7 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1oas |
| Chain | Residue | Details |
| G | SER255 | |
| G | LYS41 |
| site_id | CSA8 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1oas |
| Chain | Residue | Details |
| H | SER255 | |
| H | LYS41 |
| site_id | CSA9 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1oas |
| Chain | Residue | Details |
| A | LYS41 |
