2J9L

Cytoplasmic Domain of the Human Chloride Transporter ClC-5 in complex with ATP

Functional Information from PDB Data

site_id	AC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CL A1753

Chain	Residue
A	ARG718
B	ARG718

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site_id	AC2
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CL B3001

Chain	Residue
B	ARG630

---

site_id	AC3
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CL C1756

Chain	Residue
C	ASN716
D	ARG630

---

site_id	AC4
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CL D1754

Chain	Residue
C	ARG718
D	ARG718

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site_id	AC5
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CL D1755

Chain	Residue
D	ARG589

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site_id	AC6
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CL D3001

Chain	Residue
D	ASN716
C	ARG630

---

site_id	AC7
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CL E1753

Chain	Residue
E	ARG630

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site_id	AC8
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CL F1751

Chain	Residue
F	ARG630

---

site_id	AC9
Number of Residues	15
Details	BINDING SITE FOR RESIDUE ATP A1752

Chain	Residue
A	LYS587
A	LEU595
A	THR596
A	THR616
A	TYR617
A	SER618
A	GLY619
A	ILE722
A	THR724
A	LYS726
A	ASP727
A	HOH2009
A	HOH2041
A	HOH2042
A	HOH2043

---

site_id	BC1
Number of Residues	18
Details	BINDING SITE FOR RESIDUE ATP B1754

Chain	Residue
B	LYS587
B	LEU595
B	THR596
B	TYR617
B	SER618
B	GLY619
B	PRO621
B	ILE722
B	THR724
B	LYS726
B	ASP727
B	HOH2039
B	HOH2040
B	HOH2041
B	HOH2042
B	HOH2043
B	HOH2044
B	HOH2045

---

site_id	BC2
Number of Residues	17
Details	BINDING SITE FOR RESIDUE ATP C1755

Chain	Residue
C	LYS587
C	LEU595
C	THR596
C	THR616
C	TYR617
C	SER618
C	GLY619
C	ILE722
C	THR724
C	LYS726
C	ASP727
C	HOH2059
C	HOH2063
C	HOH2064
C	HOH2065
C	HOH2066
C	HOH2067

---

site_id	BC3
Number of Residues	15
Details	BINDING SITE FOR RESIDUE ATP D1753

Chain	Residue
D	LYS587
D	LEU595
D	THR596
D	THR616
D	TYR617
D	SER618
D	GLY619
D	THR724
D	LYS726
D	ASP727
D	HOH2054
D	HOH2055
D	HOH2056
D	HOH2057
D	HOH2058

---

site_id	BC4
Number of Residues	14
Details	BINDING SITE FOR RESIDUE ATP E1752

Chain	Residue
E	LYS587
E	LEU595
E	THR596
E	TYR617
E	SER618
E	GLY619
E	PRO621
E	ILE722
E	THR724
E	LYS726
E	ASP727
E	HOH2028
E	HOH2032
E	HOH2033

---

site_id	BC5
Number of Residues	13
Details	BINDING SITE FOR RESIDUE ATP F1750

Chain	Residue
F	THR724
F	LYS726
F	ASP727
F	HOH2005
F	HOH2021
F	LYS587
F	LEU595
F	THR596
F	TYR617
F	SER618
F	GLY619
F	PRO621
F	ILE722

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	320
Details	Domain: {"description":"CBS 1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00703","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	36
Details	Binding site: {"evidences":[{"source":"PubMed","id":"17195847","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2J9L","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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