2J9C
Structure of GlnK1 with bound effectors indicates regulatory mechanism for ammonia uptake
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0005515 | molecular_function | protein binding |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0006808 | biological_process | regulation of nitrogen utilization |
| A | 0030234 | molecular_function | enzyme regulator activity |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0005515 | molecular_function | protein binding |
| B | 0005524 | molecular_function | ATP binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005829 | cellular_component | cytosol |
| B | 0006808 | biological_process | regulation of nitrogen utilization |
| B | 0030234 | molecular_function | enzyme regulator activity |
| C | 0000166 | molecular_function | nucleotide binding |
| C | 0005515 | molecular_function | protein binding |
| C | 0005524 | molecular_function | ATP binding |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0005829 | cellular_component | cytosol |
| C | 0006808 | biological_process | regulation of nitrogen utilization |
| C | 0030234 | molecular_function | enzyme regulator activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MG A1117 |
| Chain | Residue |
| A | ATP1116 |
| A | HOH2077 |
| A | HOH2090 |
| A | HOH2177 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL A1118 |
| Chain | Residue |
| A | LYS3 |
| B | LYS3 |
| C | LYS3 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL A1119 |
| Chain | Residue |
| A | HOH2170 |
| A | LYS18 |
| A | GLU107 |
| site_id | AC4 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE ACT A1121 |
| Chain | Residue |
| A | SER31 |
| A | GLU32 |
| A | VAL33 |
| A | ACT1122 |
| B | SER31 |
| B | GLU32 |
| C | SER31 |
| C | GLU32 |
| site_id | AC5 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE ACT A1122 |
| Chain | Residue |
| A | SER31 |
| A | LYS60 |
| A | ACT1121 |
| B | SER31 |
| B | LYS60 |
| C | SER31 |
| C | LYS60 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MG B1117 |
| Chain | Residue |
| B | ATP1116 |
| B | HOH2062 |
| B | HOH2065 |
| B | HOH2070 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL B1118 |
| Chain | Residue |
| A | LEU112 |
| B | VAL38 |
| B | LYS90 |
| B | ATP1116 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MG C1117 |
| Chain | Residue |
| C | ATP1116 |
| C | HOH2061 |
| C | HOH2071 |
| C | HOH2145 |
| site_id | AC9 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL C1118 |
| Chain | Residue |
| A | VAL70 |
| C | ARG98 |
| C | HOH2055 |
| site_id | BC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ACT C1120 |
| Chain | Residue |
| C | LYS34 |
| C | TYR51 |
| C | PRO57 |
| C | HOH2077 |
| site_id | BC2 |
| Number of Residues | 26 |
| Details | BINDING SITE FOR RESIDUE ATP A1116 |
| Chain | Residue |
| A | ILE7 |
| A | GLY35 |
| A | ARG36 |
| A | GLY37 |
| A | VAL38 |
| A | LYS58 |
| A | PRO86 |
| A | GLY87 |
| A | ASP88 |
| A | GLY89 |
| A | LYS90 |
| A | MG1117 |
| A | HOH2077 |
| A | HOH2090 |
| A | HOH2091 |
| A | HOH2175 |
| A | HOH2176 |
| A | HOH2177 |
| A | HOH2178 |
| C | MET28 |
| C | THR29 |
| C | GLU62 |
| C | VAL64 |
| C | ARG101 |
| C | ARG103 |
| C | HIS115 |
| site_id | BC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO A1120 |
| Chain | Residue |
| A | GLN39 |
| A | HOH2179 |
| C | SER21 |
| C | HOH2032 |
| site_id | BC4 |
| Number of Residues | 27 |
| Details | BINDING SITE FOR RESIDUE ATP B1116 |
| Chain | Residue |
| B | HOH2153 |
| B | HOH2154 |
| A | GLY27 |
| A | MET28 |
| A | THR29 |
| A | GLU62 |
| A | VAL64 |
| A | ARG101 |
| A | ARG103 |
| A | HIS115 |
| B | ILE7 |
| B | GLY35 |
| B | ARG36 |
| B | GLY37 |
| B | VAL38 |
| B | LYS58 |
| B | PRO86 |
| B | GLY87 |
| B | ASP88 |
| B | GLY89 |
| B | LYS90 |
| B | MG1117 |
| B | CL1118 |
| B | HOH2062 |
| B | HOH2065 |
| B | HOH2070 |
| B | HOH2072 |
| site_id | BC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO B1119 |
| Chain | Residue |
| B | ARG103 |
| B | HOH2155 |
| C | ARG82 |
| C | GLY84 |
| C | HOH2091 |
| site_id | BC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO B1120 |
| Chain | Residue |
| B | LYS105 |
| B | HOH2157 |
| B | HOH2158 |
| C | GLU14 |
| C | HOH2015 |
| site_id | BC7 |
| Number of Residues | 26 |
| Details | BINDING SITE FOR RESIDUE ATP C1116 |
| Chain | Residue |
| B | GLY27 |
| B | MET28 |
| B | THR29 |
| B | GLU62 |
| B | VAL64 |
| B | ARG101 |
| B | ARG103 |
| B | HIS115 |
| C | ILE7 |
| C | GLY35 |
| C | ARG36 |
| C | GLY37 |
| C | VAL38 |
| C | LYS58 |
| C | PRO86 |
| C | GLY87 |
| C | ASP88 |
| C | GLY89 |
| C | LYS90 |
| C | MG1117 |
| C | HOH2061 |
| C | HOH2071 |
| C | HOH2144 |
| C | HOH2145 |
| C | HOH2146 |
| C | HOH2147 |
| site_id | BC8 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO C1119 |
| Chain | Residue |
| C | GLU32 |
| C | VAL33 |
| C | LYS34 |
| C | LYS58 |
| C | HOH2148 |
| C | HOH2149 |
| C | HOH2150 |
Functional Information from PROSITE/UniProt
| site_id | PS00638 |
| Number of Residues | 14 |
| Details | PII_GLNB_CTER P-II protein C-terminal region signature. TgnpGDGKIFVipV |
| Chain | Residue | Details |
| A | THR83-VAL96 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 27 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"17203075","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2J9C","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2J9E","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 6 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"17203075","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 6 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"17203075","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2J9D","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
