2J7A
Crystal structure of cytochrome c nitrite reductase NrfHA complex from Desulfovibrio vulgaris
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0019645 | biological_process | anaerobic electron transport chain |
| A | 0020037 | molecular_function | heme binding |
| A | 0030288 | cellular_component | outer membrane-bounded periplasmic space |
| A | 0042279 | molecular_function | nitrite reductase (cytochrome, ammonia-forming) activity |
| A | 0042597 | cellular_component | periplasmic space |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0005886 | cellular_component | plasma membrane |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0019645 | biological_process | anaerobic electron transport chain |
| B | 0020037 | molecular_function | heme binding |
| B | 0030288 | cellular_component | outer membrane-bounded periplasmic space |
| B | 0042279 | molecular_function | nitrite reductase (cytochrome, ammonia-forming) activity |
| B | 0042597 | cellular_component | periplasmic space |
| B | 0046872 | molecular_function | metal ion binding |
| C | 0005886 | cellular_component | plasma membrane |
| C | 0009055 | molecular_function | electron transfer activity |
| C | 0009061 | biological_process | anaerobic respiration |
| C | 0016020 | cellular_component | membrane |
| C | 0019333 | biological_process | denitrification pathway |
| C | 0020037 | molecular_function | heme binding |
| C | 0046872 | molecular_function | metal ion binding |
| D | 0005886 | cellular_component | plasma membrane |
| D | 0016491 | molecular_function | oxidoreductase activity |
| D | 0019645 | biological_process | anaerobic electron transport chain |
| D | 0020037 | molecular_function | heme binding |
| D | 0030288 | cellular_component | outer membrane-bounded periplasmic space |
| D | 0042279 | molecular_function | nitrite reductase (cytochrome, ammonia-forming) activity |
| D | 0042597 | cellular_component | periplasmic space |
| D | 0046872 | molecular_function | metal ion binding |
| E | 0005886 | cellular_component | plasma membrane |
| E | 0016491 | molecular_function | oxidoreductase activity |
| E | 0019645 | biological_process | anaerobic electron transport chain |
| E | 0020037 | molecular_function | heme binding |
| E | 0030288 | cellular_component | outer membrane-bounded periplasmic space |
| E | 0042279 | molecular_function | nitrite reductase (cytochrome, ammonia-forming) activity |
| E | 0042597 | cellular_component | periplasmic space |
| E | 0046872 | molecular_function | metal ion binding |
| F | 0005886 | cellular_component | plasma membrane |
| F | 0009055 | molecular_function | electron transfer activity |
| F | 0009061 | biological_process | anaerobic respiration |
| F | 0016020 | cellular_component | membrane |
| F | 0019333 | biological_process | denitrification pathway |
| F | 0020037 | molecular_function | heme binding |
| F | 0046872 | molecular_function | metal ion binding |
| G | 0005886 | cellular_component | plasma membrane |
| G | 0016491 | molecular_function | oxidoreductase activity |
| G | 0019645 | biological_process | anaerobic electron transport chain |
| G | 0020037 | molecular_function | heme binding |
| G | 0030288 | cellular_component | outer membrane-bounded periplasmic space |
| G | 0042279 | molecular_function | nitrite reductase (cytochrome, ammonia-forming) activity |
| G | 0042597 | cellular_component | periplasmic space |
| G | 0046872 | molecular_function | metal ion binding |
| H | 0005886 | cellular_component | plasma membrane |
| H | 0016491 | molecular_function | oxidoreductase activity |
| H | 0019645 | biological_process | anaerobic electron transport chain |
| H | 0020037 | molecular_function | heme binding |
| H | 0030288 | cellular_component | outer membrane-bounded periplasmic space |
| H | 0042279 | molecular_function | nitrite reductase (cytochrome, ammonia-forming) activity |
| H | 0042597 | cellular_component | periplasmic space |
| H | 0046872 | molecular_function | metal ion binding |
| I | 0005886 | cellular_component | plasma membrane |
| I | 0009055 | molecular_function | electron transfer activity |
| I | 0009061 | biological_process | anaerobic respiration |
| I | 0016020 | cellular_component | membrane |
| I | 0019333 | biological_process | denitrification pathway |
| I | 0020037 | molecular_function | heme binding |
| I | 0046872 | molecular_function | metal ion binding |
| J | 0005886 | cellular_component | plasma membrane |
| J | 0016491 | molecular_function | oxidoreductase activity |
| J | 0019645 | biological_process | anaerobic electron transport chain |
| J | 0020037 | molecular_function | heme binding |
| J | 0030288 | cellular_component | outer membrane-bounded periplasmic space |
| J | 0042279 | molecular_function | nitrite reductase (cytochrome, ammonia-forming) activity |
| J | 0042597 | cellular_component | periplasmic space |
| J | 0046872 | molecular_function | metal ion binding |
| K | 0005886 | cellular_component | plasma membrane |
| K | 0016491 | molecular_function | oxidoreductase activity |
| K | 0019645 | biological_process | anaerobic electron transport chain |
| K | 0020037 | molecular_function | heme binding |
| K | 0030288 | cellular_component | outer membrane-bounded periplasmic space |
| K | 0042279 | molecular_function | nitrite reductase (cytochrome, ammonia-forming) activity |
| K | 0042597 | cellular_component | periplasmic space |
| K | 0046872 | molecular_function | metal ion binding |
| L | 0005886 | cellular_component | plasma membrane |
| L | 0009055 | molecular_function | electron transfer activity |
| L | 0009061 | biological_process | anaerobic respiration |
| L | 0016020 | cellular_component | membrane |
| L | 0019333 | biological_process | denitrification pathway |
| L | 0020037 | molecular_function | heme binding |
| L | 0046872 | molecular_function | metal ion binding |
| M | 0005886 | cellular_component | plasma membrane |
| M | 0016491 | molecular_function | oxidoreductase activity |
| M | 0019645 | biological_process | anaerobic electron transport chain |
| M | 0020037 | molecular_function | heme binding |
| M | 0030288 | cellular_component | outer membrane-bounded periplasmic space |
| M | 0042279 | molecular_function | nitrite reductase (cytochrome, ammonia-forming) activity |
| M | 0042597 | cellular_component | periplasmic space |
| M | 0046872 | molecular_function | metal ion binding |
| N | 0005886 | cellular_component | plasma membrane |
| N | 0016491 | molecular_function | oxidoreductase activity |
| N | 0019645 | biological_process | anaerobic electron transport chain |
| N | 0020037 | molecular_function | heme binding |
| N | 0030288 | cellular_component | outer membrane-bounded periplasmic space |
| N | 0042279 | molecular_function | nitrite reductase (cytochrome, ammonia-forming) activity |
| N | 0042597 | cellular_component | periplasmic space |
| N | 0046872 | molecular_function | metal ion binding |
| O | 0005886 | cellular_component | plasma membrane |
| O | 0009055 | molecular_function | electron transfer activity |
| O | 0009061 | biological_process | anaerobic respiration |
| O | 0016020 | cellular_component | membrane |
| O | 0019333 | biological_process | denitrification pathway |
| O | 0020037 | molecular_function | heme binding |
| O | 0046872 | molecular_function | metal ion binding |
| P | 0005886 | cellular_component | plasma membrane |
| P | 0016491 | molecular_function | oxidoreductase activity |
| P | 0019645 | biological_process | anaerobic electron transport chain |
| P | 0020037 | molecular_function | heme binding |
| P | 0030288 | cellular_component | outer membrane-bounded periplasmic space |
| P | 0042279 | molecular_function | nitrite reductase (cytochrome, ammonia-forming) activity |
| P | 0042597 | cellular_component | periplasmic space |
| P | 0046872 | molecular_function | metal ion binding |
| Q | 0005886 | cellular_component | plasma membrane |
| Q | 0016491 | molecular_function | oxidoreductase activity |
| Q | 0019645 | biological_process | anaerobic electron transport chain |
| Q | 0020037 | molecular_function | heme binding |
| Q | 0030288 | cellular_component | outer membrane-bounded periplasmic space |
| Q | 0042279 | molecular_function | nitrite reductase (cytochrome, ammonia-forming) activity |
| Q | 0042597 | cellular_component | periplasmic space |
| Q | 0046872 | molecular_function | metal ion binding |
| R | 0005886 | cellular_component | plasma membrane |
| R | 0009055 | molecular_function | electron transfer activity |
| R | 0009061 | biological_process | anaerobic respiration |
| R | 0016020 | cellular_component | membrane |
| R | 0019333 | biological_process | denitrification pathway |
| R | 0020037 | molecular_function | heme binding |
| R | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA A1006 |
| Chain | Residue |
| A | GLU235 |
| A | TYR236 |
| A | LYS295 |
| A | GLN297 |
| A | HOH2098 |
| A | HOH2101 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA A1007 |
| Chain | Residue |
| A | HEC1003 |
| A | HEC1004 |
| A | HOH2195 |
| A | GLY78 |
| A | GLU117 |
| A | ALA118 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA B1006 |
| Chain | Residue |
| B | GLU235 |
| B | TYR236 |
| B | LYS295 |
| B | GLN297 |
| B | HOH2101 |
| B | HOH2105 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CA B1007 |
| Chain | Residue |
| B | GLY78 |
| B | GLU117 |
| B | ALA118 |
| B | HEC1003 |
| B | HEC1004 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ACT C1006 |
| Chain | Residue |
| A | HOH2118 |
| C | HIS120 |
| C | HEC1003 |
| F | HEC1003 |
| F | HEC1004 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA D1006 |
| Chain | Residue |
| D | GLU235 |
| D | TYR236 |
| D | LYS295 |
| D | GLN297 |
| D | HOH2092 |
| D | HOH2095 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CA D1007 |
| Chain | Residue |
| D | GLY78 |
| D | GLU117 |
| D | ALA118 |
| D | HEC1003 |
| D | HEC1004 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CA E1006 |
| Chain | Residue |
| E | GLU235 |
| E | TYR236 |
| E | LYS295 |
| E | GLN297 |
| E | HOH2085 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CA E1007 |
| Chain | Residue |
| E | GLY78 |
| E | GLU117 |
| E | ALA118 |
| E | HEC1003 |
| E | HEC1004 |
| site_id | BC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA G1006 |
| Chain | Residue |
| G | GLU235 |
| G | TYR236 |
| G | LYS295 |
| G | GLN297 |
| G | HOH2074 |
| G | HOH2080 |
| site_id | BC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA G1007 |
| Chain | Residue |
| G | GLY78 |
| G | GLU117 |
| G | ALA118 |
| G | HEC1003 |
| G | HEC1004 |
| G | HOH2155 |
| site_id | BC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA H1006 |
| Chain | Residue |
| H | GLU235 |
| H | TYR236 |
| H | LYS295 |
| H | GLN297 |
| H | HOH2103 |
| H | HOH2104 |
| site_id | BC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CA H1007 |
| Chain | Residue |
| H | GLY78 |
| H | GLU117 |
| H | ALA118 |
| H | HEC1003 |
| H | HEC1004 |
| site_id | BC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ACT I1006 |
| Chain | Residue |
| I | HEC1003 |
| I | HEC1004 |
| L | HEC1003 |
| L | HEC1004 |
| site_id | BC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA J1006 |
| Chain | Residue |
| J | GLU235 |
| J | TYR236 |
| J | LYS295 |
| J | GLN297 |
| J | HOH2087 |
| J | HOH2088 |
| site_id | BC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA J1007 |
| Chain | Residue |
| J | GLY78 |
| J | GLU117 |
| J | ALA118 |
| J | HEC1003 |
| J | HEC1004 |
| J | HOH2165 |
| site_id | BC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA K1006 |
| Chain | Residue |
| K | GLU235 |
| K | TYR236 |
| K | LYS295 |
| K | GLN297 |
| K | HOH2043 |
| K | HOH2048 |
| site_id | BC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CA K1007 |
| Chain | Residue |
| K | GLY78 |
| K | GLU117 |
| K | ALA118 |
| K | HEC1003 |
| K | HEC1004 |
| site_id | CC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA M1006 |
| Chain | Residue |
| M | GLU235 |
| M | TYR236 |
| M | LYS295 |
| M | GLN297 |
| M | HOH2103 |
| M | HOH2104 |
| site_id | CC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA M1007 |
| Chain | Residue |
| M | GLY78 |
| M | GLU117 |
| M | ALA118 |
| M | HEC1003 |
| M | HEC1004 |
| M | HOH2200 |
| site_id | CC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA N1006 |
| Chain | Residue |
| N | GLU235 |
| N | TYR236 |
| N | LYS295 |
| N | GLN297 |
| N | HOH2112 |
| N | HOH2113 |
| site_id | CC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CA N1007 |
| Chain | Residue |
| N | GLY78 |
| N | GLU117 |
| N | ALA118 |
| N | HEC1003 |
| N | HEC1004 |
| site_id | CC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ACT O1006 |
| Chain | Residue |
| O | HEC1003 |
| P | HOH2111 |
| R | HEC1003 |
| R | HEC1004 |
| site_id | CC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA P1006 |
| Chain | Residue |
| P | GLU235 |
| P | TYR236 |
| P | LYS295 |
| P | GLN297 |
| P | HOH2094 |
| P | HOH2098 |
| site_id | CC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CA P1007 |
| Chain | Residue |
| P | GLY78 |
| P | GLU117 |
| P | ALA118 |
| P | HEC1003 |
| P | HEC1004 |
| site_id | CC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CA Q1006 |
| Chain | Residue |
| Q | GLU235 |
| Q | TYR236 |
| Q | LYS295 |
| Q | GLN297 |
| Q | HOH2062 |
| site_id | CC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CA Q1007 |
| Chain | Residue |
| Q | GLY78 |
| Q | GLU117 |
| Q | ALA118 |
| Q | HEC1003 |
| Q | HEC1004 |
| site_id | DC1 |
| Number of Residues | 20 |
| Details | BINDING SITE FOR RESIDUE HEM A1001 |
| Chain | Residue |
| A | TYR115 |
| A | ARG116 |
| A | ALA118 |
| A | PHE128 |
| A | ILE131 |
| A | ARG133 |
| A | CYS147 |
| A | CYS150 |
| A | LYS151 |
| A | CYS232 |
| A | HIS233 |
| A | TYR236 |
| A | HIS298 |
| A | ASN429 |
| A | HEC1003 |
| A | HOH2032 |
| A | HOH2034 |
| A | HOH2103 |
| A | HOH2187 |
| A | HOH2188 |
| site_id | DC2 |
| Number of Residues | 23 |
| Details | BINDING SITE FOR RESIDUE HEM A1002 |
| Chain | Residue |
| A | TYR39 |
| A | PHE57 |
| A | GLN60 |
| A | TYR64 |
| A | GLY186 |
| A | CYS187 |
| A | CYS190 |
| A | HIS191 |
| A | MET196 |
| A | LEU198 |
| A | ARG221 |
| A | ARG225 |
| A | MET321 |
| A | ILE332 |
| A | SER333 |
| A | HIS335 |
| A | TRP337 |
| A | HEC1003 |
| A | HOH2117 |
| A | HOH2189 |
| A | HOH2190 |
| A | HOH2191 |
| C | VAL127 |
| site_id | DC3 |
| Number of Residues | 25 |
| Details | BINDING SITE FOR RESIDUE HEM A1003 |
| Chain | Residue |
| A | GLY78 |
| A | SER79 |
| A | ALA118 |
| A | ARG119 |
| A | GLY120 |
| A | HIS121 |
| A | TYR123 |
| A | ALA124 |
| A | ASP127 |
| A | CYS150 |
| A | ILE185 |
| A | THR189 |
| A | VAL228 |
| A | CYS229 |
| A | CYS232 |
| A | HIS233 |
| A | HIS320 |
| A | TRP337 |
| A | THR338 |
| A | HEC1001 |
| A | HEC1002 |
| A | HEC1004 |
| A | CA1007 |
| A | HOH2192 |
| A | HOH2193 |
| site_id | DC4 |
| Number of Residues | 24 |
| Details | BINDING SITE FOR RESIDUE HEM A1004 |
| Chain | Residue |
| A | THR74 |
| A | LYS77 |
| A | GLY78 |
| A | GLU117 |
| A | HIS233 |
| A | TRP304 |
| A | HIS309 |
| A | VAL314 |
| A | THR315 |
| A | CYS316 |
| A | CYS319 |
| A | HIS320 |
| A | SER339 |
| A | PRO340 |
| A | MET341 |
| A | GLN369 |
| A | ASN429 |
| A | PHE433 |
| A | HIS434 |
| A | HEC1003 |
| A | CA1007 |
| A | HOH2194 |
| A | HOH2195 |
| A | HOH2196 |
| site_id | DC5 |
| Number of Residues | 20 |
| Details | BINDING SITE FOR RESIDUE HEM A1005 |
| Chain | Residue |
| A | HIS309 |
| A | VAL314 |
| A | PRO340 |
| A | ALA348 |
| A | CYS349 |
| A | CYS352 |
| A | HIS353 |
| A | ARG364 |
| A | VAL365 |
| A | HOH2197 |
| A | HOH2198 |
| A | HOH2199 |
| A | HOH2200 |
| A | HOH2201 |
| B | HIS353 |
| B | LYS356 |
| B | HEC1005 |
| B | HOH2183 |
| C | ARG141 |
| C | MET148 |
| site_id | DC6 |
| Number of Residues | 21 |
| Details | BINDING SITE FOR RESIDUE HEM B1001 |
| Chain | Residue |
| B | TYR115 |
| B | ARG116 |
| B | ALA118 |
| B | PHE128 |
| B | ILE131 |
| B | ARG133 |
| B | CYS147 |
| B | CYS150 |
| B | LYS151 |
| B | CYS232 |
| B | HIS233 |
| B | TYR236 |
| B | HIS298 |
| B | ASN429 |
| B | HEC1003 |
| B | HOH2031 |
| B | HOH2046 |
| B | HOH2176 |
| B | HOH2177 |
| B | HOH2178 |
| B | HOH2179 |
| site_id | DC7 |
| Number of Residues | 21 |
| Details | BINDING SITE FOR RESIDUE HEM B1002 |
| Chain | Residue |
| B | TYR39 |
| B | PHE57 |
| B | GLN60 |
| B | TYR64 |
| B | GLY186 |
| B | CYS187 |
| B | CYS190 |
| B | HIS191 |
| B | MET196 |
| B | ARG221 |
| B | ARG225 |
| B | MET321 |
| B | TYR323 |
| B | ILE332 |
| B | SER333 |
| B | HIS335 |
| B | TRP337 |
| B | HEC1003 |
| B | HOH2118 |
| B | HOH2180 |
| C | ALA157 |
| site_id | DC8 |
| Number of Residues | 25 |
| Details | BINDING SITE FOR RESIDUE HEM B1003 |
| Chain | Residue |
| B | GLY78 |
| B | SER79 |
| B | ALA118 |
| B | ARG119 |
| B | HIS121 |
| B | TYR123 |
| B | ALA124 |
| B | ASP127 |
| B | CYS150 |
| B | LYS151 |
| B | ILE185 |
| B | THR189 |
| B | VAL228 |
| B | CYS229 |
| B | CYS232 |
| B | HIS233 |
| B | HIS320 |
| B | TRP337 |
| B | THR338 |
| B | HEC1001 |
| B | HEC1002 |
| B | HEC1004 |
| B | CA1007 |
| B | HOH2181 |
| B | HOH2182 |
| site_id | DC9 |
| Number of Residues | 23 |
| Details | BINDING SITE FOR RESIDUE HEM B1004 |
| Chain | Residue |
| B | THR74 |
| B | LYS77 |
| B | GLY78 |
| B | GLU117 |
| B | HIS233 |
| B | TRP304 |
| B | HIS309 |
| B | VAL314 |
| B | THR315 |
| B | CYS316 |
| B | CYS319 |
| B | HIS320 |
| B | SER339 |
| B | PRO340 |
| B | MET341 |
| B | GLN369 |
| B | ASN429 |
| B | PHE433 |
| B | HIS434 |
| B | HEC1003 |
| B | CA1007 |
| B | HOH2137 |
| B | HOH2182 |
| site_id | EC1 |
| Number of Residues | 23 |
| Details | BINDING SITE FOR RESIDUE HEM B1005 |
| Chain | Residue |
| A | THR308 |
| A | HIS353 |
| A | LYS356 |
| A | HEC1005 |
| B | HIS309 |
| B | VAL314 |
| B | ASP318 |
| B | CYS319 |
| B | PRO340 |
| B | ALA348 |
| B | CYS349 |
| B | CYS352 |
| B | HIS353 |
| B | ARG364 |
| B | VAL365 |
| B | HOH2183 |
| B | HOH2184 |
| B | HOH2185 |
| B | HOH2186 |
| B | HOH2187 |
| B | HOH2188 |
| C | MET148 |
| C | LYS149 |
| site_id | EC2 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE HEM C1001 |
| Chain | Residue |
| C | THR37 |
| C | CYS43 |
| C | CYS46 |
| C | ILE48 |
| C | MET49 |
| C | ASN67 |
| C | HIS70 |
| C | ASP89 |
| C | MET92 |
| C | ASN93 |
| C | LEU103 |
| C | ALA104 |
| C | GLY105 |
| C | THR108 |
| C | HEC1002 |
| site_id | EC3 |
| Number of Residues | 19 |
| Details | BINDING SITE FOR RESIDUE HEM C1002 |
| Chain | Residue |
| C | ARG40 |
| C | CYS43 |
| C | MET49 |
| C | VAL52 |
| C | HIS56 |
| C | HIS61 |
| C | SER65 |
| C | CYS66 |
| C | CYS69 |
| C | HIS70 |
| C | ILE102 |
| C | LYS109 |
| C | VAL112 |
| C | THR137 |
| C | GLN144 |
| C | HIS145 |
| C | HEC1001 |
| C | HOH2022 |
| C | HOH2047 |
| site_id | EC4 |
| Number of Residues | 20 |
| Details | BINDING SITE FOR RESIDUE HEM C1003 |
| Chain | Residue |
| C | GLY60 |
| C | HIS61 |
| C | ASP68 |
| C | VAL112 |
| C | ASN115 |
| C | CYS116 |
| C | CYS119 |
| C | HIS120 |
| C | HIS140 |
| C | VAL143 |
| C | HEC1004 |
| C | ACT1006 |
| C | HOH2012 |
| C | HOH2048 |
| C | HOH2049 |
| D | LYS329 |
| F | CYS119 |
| F | HIS120 |
| F | MET122 |
| F | THR123 |
| site_id | EC5 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE HEM C1004 |
| Chain | Residue |
| A | TYR323 |
| A | ARG325 |
| A | LYS331 |
| A | GLN351 |
| A | HOH2119 |
| C | CYS116 |
| C | HIS120 |
| C | ASN124 |
| C | SER129 |
| C | LYS133 |
| C | CYS136 |
| C | CYS139 |
| C | HIS140 |
| C | HEC1003 |
| D | ARG325 |
| D | LYS329 |
| F | HEC1004 |
| site_id | EC6 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE LMT C1005 |
| Chain | Residue |
| A | GLY26 |
| A | SER28 |
| A | ASP29 |
| A | VAL30 |
| C | HIS73 |
| C | ASN74 |
| C | LEU75 |
| C | ALA118 |
| C | HOH2050 |
| site_id | EC7 |
| Number of Residues | 20 |
| Details | BINDING SITE FOR RESIDUE HEM D1001 |
| Chain | Residue |
| D | TYR115 |
| D | ARG116 |
| D | ALA118 |
| D | PHE128 |
| D | ILE131 |
| D | ARG133 |
| D | CYS147 |
| D | CYS150 |
| D | LYS151 |
| D | CYS232 |
| D | HIS233 |
| D | TYR236 |
| D | PHE238 |
| D | HIS298 |
| D | ASN429 |
| D | HEC1003 |
| D | HOH2038 |
| D | HOH2158 |
| D | HOH2159 |
| D | HOH2160 |
| site_id | EC8 |
| Number of Residues | 24 |
| Details | BINDING SITE FOR RESIDUE HEM D1002 |
| Chain | Residue |
| D | TYR39 |
| D | PHE57 |
| D | GLN60 |
| D | TYR61 |
| D | TYR64 |
| D | GLY186 |
| D | CYS187 |
| D | CYS190 |
| D | HIS191 |
| D | MET196 |
| D | LEU198 |
| D | ARG221 |
| D | ARG225 |
| D | MET321 |
| D | ILE332 |
| D | SER333 |
| D | HIS335 |
| D | TRP337 |
| D | HEC1003 |
| D | HOH2108 |
| D | HOH2161 |
| D | HOH2162 |
| F | GLU126 |
| F | VAL127 |
| site_id | EC9 |
| Number of Residues | 25 |
| Details | BINDING SITE FOR RESIDUE HEM D1003 |
| Chain | Residue |
| D | GLY78 |
| D | SER79 |
| D | ALA118 |
| D | ARG119 |
| D | GLY120 |
| D | HIS121 |
| D | TYR123 |
| D | ALA124 |
| D | ASP127 |
| D | CYS150 |
| D | ILE185 |
| D | VAL228 |
| D | CYS229 |
| D | CYS232 |
| D | HIS233 |
| D | HIS320 |
| D | MET321 |
| D | TRP337 |
| D | THR338 |
| D | HEC1001 |
| D | HEC1002 |
| D | HEC1004 |
| D | CA1007 |
| D | HOH2039 |
| D | HOH2163 |
| site_id | FC1 |
| Number of Residues | 23 |
| Details | BINDING SITE FOR RESIDUE HEM D1004 |
| Chain | Residue |
| D | THR74 |
| D | LYS77 |
| D | GLY78 |
| D | GLU117 |
| D | CYS229 |
| D | HIS233 |
| D | TRP304 |
| D | HIS309 |
| D | VAL314 |
| D | THR315 |
| D | CYS316 |
| D | CYS319 |
| D | HIS320 |
| D | SER339 |
| D | MET341 |
| D | GLN369 |
| D | ASN429 |
| D | PHE433 |
| D | HIS434 |
| D | HEC1003 |
| D | CA1007 |
| D | HOH2164 |
| D | HOH2165 |
| site_id | FC2 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE HEM D1005 |
| Chain | Residue |
| D | HIS309 |
| D | VAL314 |
| D | ALA348 |
| D | CYS349 |
| D | CYS352 |
| D | HIS353 |
| D | ARG364 |
| D | VAL365 |
| D | HOH2125 |
| D | HOH2166 |
| D | HOH2167 |
| D | HOH2168 |
| D | HOH2169 |
| D | HOH2170 |
| E | HIS353 |
| E | LYS356 |
| F | ARG141 |
| site_id | FC3 |
| Number of Residues | 21 |
| Details | BINDING SITE FOR RESIDUE HEM E1001 |
| Chain | Residue |
| E | TYR115 |
| E | ARG116 |
| E | ALA118 |
| E | PHE128 |
| E | ILE131 |
| E | ARG133 |
| E | CYS147 |
| E | CYS150 |
| E | LYS151 |
| E | CYS232 |
| E | HIS233 |
| E | TYR236 |
| E | HIS298 |
| E | ASN429 |
| E | HEC1003 |
| E | HOH2045 |
| E | HOH2049 |
| E | HOH2070 |
| E | HOH2149 |
| E | HOH2150 |
| E | HOH2151 |
| site_id | FC4 |
| Number of Residues | 22 |
| Details | BINDING SITE FOR RESIDUE HEM E1002 |
| Chain | Residue |
| E | TYR39 |
| E | PHE57 |
| E | GLN60 |
| E | TYR61 |
| E | TYR64 |
| E | GLY186 |
| E | CYS187 |
| E | CYS190 |
| E | HIS191 |
| E | MET196 |
| E | LEU198 |
| E | ARG221 |
| E | ARG225 |
| E | MET321 |
| E | TYR323 |
| E | ILE332 |
| E | SER333 |
| E | HIS335 |
| E | TRP337 |
| E | HEC1003 |
| E | HOH2099 |
| F | ALA157 |
| site_id | FC5 |
| Number of Residues | 27 |
| Details | BINDING SITE FOR RESIDUE HEM E1003 |
| Chain | Residue |
| E | GLY78 |
| E | SER79 |
| E | ALA118 |
| E | ARG119 |
| E | GLY120 |
| E | HIS121 |
| E | TYR123 |
| E | ALA124 |
| E | ASP127 |
| E | CYS150 |
| E | LYS151 |
| E | ILE185 |
| E | THR189 |
| E | VAL228 |
| E | CYS229 |
| E | CYS232 |
| E | HIS233 |
| E | HIS320 |
| E | MET321 |
| E | TRP337 |
| E | THR338 |
| E | HEC1001 |
| E | HEC1002 |
| E | HEC1004 |
| E | CA1007 |
| E | HOH2039 |
| E | HOH2152 |
| site_id | FC6 |
| Number of Residues | 22 |
| Details | BINDING SITE FOR RESIDUE HEM E1004 |
| Chain | Residue |
| E | THR74 |
| E | LYS77 |
| E | GLY78 |
| E | GLU117 |
| E | HIS233 |
| E | TRP304 |
| E | HIS309 |
| E | VAL314 |
| E | THR315 |
| E | CYS316 |
| E | CYS319 |
| E | HIS320 |
| E | SER339 |
| E | MET341 |
| E | GLN369 |
| E | ASN429 |
| E | PHE433 |
| E | HIS434 |
| E | HEC1003 |
| E | HEC1005 |
| E | CA1007 |
| E | HOH2153 |
| site_id | FC7 |
| Number of Residues | 19 |
| Details | BINDING SITE FOR RESIDUE HEM E1005 |
| Chain | Residue |
| D | HIS353 |
| D | LYS356 |
| D | HOH2167 |
| E | THR308 |
| E | HIS309 |
| E | VAL314 |
| E | ASP318 |
| E | CYS319 |
| E | ALA348 |
| E | CYS349 |
| E | CYS352 |
| E | HIS353 |
| E | ARG364 |
| E | VAL365 |
| E | HEC1004 |
| E | HOH2154 |
| E | HOH2155 |
| F | MET148 |
| F | LYS149 |
| site_id | FC8 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE HEM F1001 |
| Chain | Residue |
| F | THR37 |
| F | CYS43 |
| F | CYS46 |
| F | ILE48 |
| F | MET49 |
| F | ASN67 |
| F | HIS70 |
| F | ASP89 |
| F | MET92 |
| F | PRO98 |
| F | ALA104 |
| F | GLY105 |
| F | THR108 |
| F | HEC1002 |
| site_id | FC9 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE HEM F1002 |
| Chain | Residue |
| F | ARG40 |
| F | MET49 |
| F | VAL52 |
| F | HIS56 |
| F | HIS61 |
| F | SER65 |
| F | CYS66 |
| F | CYS69 |
| F | HIS70 |
| F | LYS109 |
| F | VAL112 |
| F | THR137 |
| F | VAL143 |
| F | GLN144 |
| F | HIS145 |
| F | HEC1001 |
| F | HOH2035 |
| F | HOH2039 |
| site_id | GC1 |
| Number of Residues | 19 |
| Details | BINDING SITE FOR RESIDUE HEM F1003 |
| Chain | Residue |
| A | LYS329 |
| C | CYS119 |
| C | HIS120 |
| C | MET122 |
| C | THR123 |
| C | ACT1006 |
| F | GLY60 |
| F | HIS61 |
| F | ASP68 |
| F | VAL112 |
| F | ASN115 |
| F | CYS116 |
| F | CYS119 |
| F | HIS120 |
| F | HIS140 |
| F | VAL143 |
| F | HOH2040 |
| F | HOH2041 |
| F | HOH2042 |
| site_id | GC2 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE HEM F1004 |
| Chain | Residue |
| A | ARG325 |
| C | HEC1004 |
| C | ACT1006 |
| D | ASP318 |
| D | TYR323 |
| D | THR324 |
| D | ARG325 |
| D | LYS331 |
| D | GLN351 |
| F | CYS116 |
| F | HIS120 |
| F | ASN124 |
| F | SER129 |
| F | CYS136 |
| F | CYS139 |
| F | HIS140 |
| site_id | GC3 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE LMT F1005 |
| Chain | Residue |
| C | LYS35 |
| D | GLY26 |
| D | SER28 |
| D | ASP29 |
| D | VAL30 |
| F | HIS73 |
| F | ASN74 |
| F | LEU75 |
| F | ALA118 |
| site_id | GC4 |
| Number of Residues | 20 |
| Details | BINDING SITE FOR RESIDUE HEM G1001 |
| Chain | Residue |
| G | TYR115 |
| G | ARG116 |
| G | ALA118 |
| G | PHE128 |
| G | ILE131 |
| G | ARG133 |
| G | CYS147 |
| G | CYS150 |
| G | LYS151 |
| G | CYS232 |
| G | HIS233 |
| G | TYR236 |
| G | HIS298 |
| G | ASN429 |
| G | HEC1003 |
| G | HOH2036 |
| G | HOH2047 |
| G | HOH2082 |
| G | HOH2148 |
| G | HOH2149 |
| site_id | GC5 |
| Number of Residues | 22 |
| Details | BINDING SITE FOR RESIDUE HEM G1002 |
| Chain | Residue |
| G | TYR39 |
| G | PHE57 |
| G | GLN60 |
| G | TYR64 |
| G | GLY186 |
| G | CYS187 |
| G | CYS190 |
| G | HIS191 |
| G | MET196 |
| G | LEU198 |
| G | ARG221 |
| G | ARG225 |
| G | MET321 |
| G | SER333 |
| G | HIS335 |
| G | TRP337 |
| G | HEC1003 |
| G | HOH2091 |
| G | HOH2150 |
| G | HOH2151 |
| I | GLU126 |
| I | VAL127 |
| site_id | GC6 |
| Number of Residues | 25 |
| Details | BINDING SITE FOR RESIDUE HEM G1003 |
| Chain | Residue |
| G | GLY78 |
| G | SER79 |
| G | ALA118 |
| G | ARG119 |
| G | GLY120 |
| G | HIS121 |
| G | TYR123 |
| G | ALA124 |
| G | ASP127 |
| G | CYS150 |
| G | ILE185 |
| G | THR189 |
| G | VAL228 |
| G | CYS229 |
| G | CYS232 |
| G | HIS233 |
| G | HIS320 |
| G | TRP337 |
| G | THR338 |
| G | HEC1001 |
| G | HEC1002 |
| G | HEC1004 |
| G | CA1007 |
| G | HOH2037 |
| G | HOH2152 |
| site_id | GC7 |
| Number of Residues | 23 |
| Details | BINDING SITE FOR RESIDUE HEM G1004 |
| Chain | Residue |
| G | THR74 |
| G | LYS77 |
| G | GLY78 |
| G | GLU117 |
| G | HIS233 |
| G | TRP304 |
| G | HIS309 |
| G | VAL314 |
| G | THR315 |
| G | CYS316 |
| G | CYS319 |
| G | HIS320 |
| G | SER339 |
| G | GLN369 |
| G | ASN429 |
| G | PHE433 |
| G | HIS434 |
| G | HEC1003 |
| G | HEC1005 |
| G | CA1007 |
| G | HOH2153 |
| G | HOH2154 |
| G | HOH2155 |
| site_id | GC8 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE HEM G1005 |
| Chain | Residue |
| G | HIS309 |
| G | ALA348 |
| G | CYS349 |
| G | CYS352 |
| G | HIS353 |
| G | ARG364 |
| G | VAL365 |
| G | HEC1004 |
| G | HOH2157 |
| G | HOH2158 |
| G | HOH2159 |
| G | HOH2160 |
| H | HIS353 |
| H | LYS356 |
| H | HEC1005 |
| H | HOH2192 |
| I | ARG141 |
| I | MET148 |
| site_id | GC9 |
| Number of Residues | 20 |
| Details | BINDING SITE FOR RESIDUE HEM H1001 |
| Chain | Residue |
| H | TYR115 |
| H | ARG116 |
| H | ASP127 |
| H | PHE128 |
| H | ILE131 |
| H | ARG133 |
| H | CYS147 |
| H | CYS150 |
| H | LYS151 |
| H | CYS232 |
| H | HIS233 |
| H | TYR236 |
| H | HIS298 |
| H | ASN429 |
| H | HEC1003 |
| H | HOH2031 |
| H | HOH2049 |
| H | HOH2184 |
| H | HOH2185 |
| H | HOH2186 |
| site_id | HC1 |
| Number of Residues | 20 |
| Details | BINDING SITE FOR RESIDUE HEM H1002 |
| Chain | Residue |
| H | TYR39 |
| H | PHE57 |
| H | GLN60 |
| H | TYR64 |
| H | GLY186 |
| H | CYS187 |
| H | CYS190 |
| H | HIS191 |
| H | MET196 |
| H | LEU198 |
| H | ARG221 |
| H | ARG225 |
| H | MET321 |
| H | ILE332 |
| H | SER333 |
| H | HIS335 |
| H | TRP337 |
| H | HEC1003 |
| H | HOH2117 |
| I | ALA157 |
| site_id | HC2 |
| Number of Residues | 25 |
| Details | BINDING SITE FOR RESIDUE HEM H1003 |
| Chain | Residue |
| H | GLY78 |
| H | SER79 |
| H | ALA118 |
| H | ARG119 |
| H | GLY120 |
| H | HIS121 |
| H | TYR123 |
| H | ALA124 |
| H | ASP127 |
| H | CYS150 |
| H | LYS151 |
| H | ILE185 |
| H | THR189 |
| H | VAL228 |
| H | CYS229 |
| H | CYS232 |
| H | HIS233 |
| H | HIS320 |
| H | TRP337 |
| H | THR338 |
| H | HEC1001 |
| H | HEC1002 |
| H | HEC1004 |
| H | CA1007 |
| H | HOH2187 |
| site_id | HC3 |
| Number of Residues | 23 |
| Details | BINDING SITE FOR RESIDUE HEM H1004 |
| Chain | Residue |
| H | THR74 |
| H | LYS77 |
| H | GLY78 |
| H | GLU117 |
| H | GLU300 |
| H | TRP304 |
| H | HIS309 |
| H | VAL314 |
| H | THR315 |
| H | CYS316 |
| H | CYS319 |
| H | HIS320 |
| H | SER339 |
| H | MET341 |
| H | GLN369 |
| H | ASN429 |
| H | PHE433 |
| H | HIS434 |
| H | HEC1003 |
| H | HEC1005 |
| H | CA1007 |
| H | HOH2139 |
| H | HOH2188 |
| site_id | HC4 |
| Number of Residues | 24 |
| Details | BINDING SITE FOR RESIDUE HEM H1005 |
| Chain | Residue |
| G | HIS353 |
| G | LYS356 |
| G | HEC1005 |
| H | HIS309 |
| H | VAL314 |
| H | ASP318 |
| H | CYS319 |
| H | PRO340 |
| H | ALA348 |
| H | CYS349 |
| H | CYS352 |
| H | HIS353 |
| H | ARG364 |
| H | VAL365 |
| H | PRO436 |
| H | HEC1004 |
| H | HOH2189 |
| H | HOH2190 |
| H | HOH2191 |
| H | HOH2192 |
| H | HOH2193 |
| H | HOH2194 |
| I | MET148 |
| I | LYS149 |
| site_id | HC5 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE HEM I1001 |
| Chain | Residue |
| I | THR37 |
| I | CYS43 |
| I | CYS46 |
| I | MET49 |
| I | ASN67 |
| I | HIS70 |
| I | ASP89 |
| I | ASN93 |
| I | ALA104 |
| I | GLY105 |
| I | THR108 |
| I | HEC1002 |
| site_id | HC6 |
| Number of Residues | 19 |
| Details | BINDING SITE FOR RESIDUE HEM I1002 |
| Chain | Residue |
| I | CYS43 |
| I | MET49 |
| I | VAL52 |
| I | HIS56 |
| I | HIS61 |
| I | SER65 |
| I | CYS66 |
| I | CYS69 |
| I | HIS70 |
| I | ILE102 |
| I | ALA104 |
| I | LYS109 |
| I | VAL112 |
| I | THR137 |
| I | GLN144 |
| I | HIS145 |
| I | HEC1001 |
| I | HOH2037 |
| I | HOH2038 |
| site_id | HC7 |
| Number of Residues | 19 |
| Details | BINDING SITE FOR RESIDUE HEM I1003 |
| Chain | Residue |
| I | GLY60 |
| I | HIS61 |
| I | ASP68 |
| I | VAL112 |
| I | ASN115 |
| I | CYS116 |
| I | CYS119 |
| I | HIS120 |
| I | HIS140 |
| I | VAL143 |
| I | HEC1004 |
| I | ACT1006 |
| I | HOH2039 |
| I | HOH2040 |
| J | LYS329 |
| L | CYS119 |
| L | HIS120 |
| L | MET122 |
| L | THR123 |
| site_id | HC8 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE HEM I1004 |
| Chain | Residue |
| G | ASP318 |
| G | TYR323 |
| G | THR324 |
| G | ARG325 |
| G | LYS331 |
| G | GLN351 |
| I | CYS116 |
| I | HIS120 |
| I | ASN124 |
| I | SER129 |
| I | CYS136 |
| I | CYS139 |
| I | HIS140 |
| I | HEC1003 |
| I | ACT1006 |
| J | ARG325 |
| J | LYS329 |
| L | HEC1004 |
| site_id | HC9 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE LMT I1005 |
| Chain | Residue |
| G | GLY26 |
| G | SER28 |
| G | ASP29 |
| G | VAL30 |
| I | HIS73 |
| I | ASN74 |
| I | LEU75 |
| I | ALA118 |
| site_id | IC1 |
| Number of Residues | 19 |
| Details | BINDING SITE FOR RESIDUE HEM J1001 |
| Chain | Residue |
| J | TYR115 |
| J | ARG116 |
| J | PHE128 |
| J | ILE131 |
| J | ARG133 |
| J | CYS147 |
| J | CYS150 |
| J | LYS151 |
| J | CYS232 |
| J | HIS233 |
| J | TYR236 |
| J | HIS298 |
| J | ASN429 |
| J | HEC1003 |
| J | HOH2034 |
| J | HOH2157 |
| J | HOH2158 |
| J | HOH2159 |
| J | HOH2160 |
| site_id | IC2 |
| Number of Residues | 25 |
| Details | BINDING SITE FOR RESIDUE HEM J1002 |
| Chain | Residue |
| J | TYR39 |
| J | PHE57 |
| J | GLN60 |
| J | TYR61 |
| J | TYR64 |
| J | GLY186 |
| J | CYS187 |
| J | CYS190 |
| J | HIS191 |
| J | MET196 |
| J | LEU198 |
| J | ARG221 |
| J | ARG225 |
| J | MET321 |
| J | ILE332 |
| J | SER333 |
| J | HIS335 |
| J | TRP337 |
| J | HEC1003 |
| J | HOH2100 |
| J | HOH2161 |
| J | HOH2162 |
| L | GLU126 |
| L | VAL127 |
| L | HOH2029 |
| site_id | IC3 |
| Number of Residues | 26 |
| Details | BINDING SITE FOR RESIDUE HEM J1003 |
| Chain | Residue |
| J | GLY78 |
| J | SER79 |
| J | ALA118 |
| J | ARG119 |
| J | GLY120 |
| J | HIS121 |
| J | TYR123 |
| J | ALA124 |
| J | ASP127 |
| J | CYS150 |
| J | ILE185 |
| J | THR189 |
| J | VAL228 |
| J | CYS229 |
| J | CYS232 |
| J | HIS233 |
| J | HIS320 |
| J | MET321 |
| J | TRP337 |
| J | THR338 |
| J | HEC1001 |
| J | HEC1002 |
| J | HEC1004 |
| J | CA1007 |
| J | HOH2036 |
| J | HOH2163 |
| site_id | IC4 |
| Number of Residues | 26 |
| Details | BINDING SITE FOR RESIDUE HEM J1004 |
| Chain | Residue |
| J | THR74 |
| J | LYS77 |
| J | GLY78 |
| J | GLU117 |
| J | CYS229 |
| J | HIS233 |
| J | TYR301 |
| J | TRP304 |
| J | HIS309 |
| J | VAL314 |
| J | THR315 |
| J | CYS316 |
| J | CYS319 |
| J | HIS320 |
| J | SER339 |
| J | MET341 |
| J | GLN369 |
| J | ASN429 |
| J | PHE433 |
| J | HIS434 |
| J | HEC1003 |
| J | HEC1005 |
| J | CA1007 |
| J | HOH2118 |
| J | HOH2164 |
| J | HOH2165 |
| site_id | IC5 |
| Number of Residues | 19 |
| Details | BINDING SITE FOR RESIDUE HEM J1005 |
| Chain | Residue |
| J | THR308 |
| J | HIS309 |
| J | ALA312 |
| J | CYS319 |
| J | ALA348 |
| J | CYS349 |
| J | CYS352 |
| J | HIS353 |
| J | ARG364 |
| J | VAL365 |
| J | HEC1004 |
| J | HOH2166 |
| J | HOH2167 |
| J | HOH2168 |
| K | HIS353 |
| K | LYS356 |
| K | HEC1005 |
| L | ARG141 |
| L | MET148 |
| site_id | IC6 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE HEM K1001 |
| Chain | Residue |
| K | TYR115 |
| K | ARG116 |
| K | ALA118 |
| K | PHE128 |
| K | ILE131 |
| K | ARG133 |
| K | CYS147 |
| K | CYS150 |
| K | LYS151 |
| K | CYS232 |
| K | HIS233 |
| K | TYR236 |
| K | HIS298 |
| K | ASN429 |
| K | HEC1003 |
| K | HOH2021 |
| K | HOH2098 |
| site_id | IC7 |
| Number of Residues | 22 |
| Details | BINDING SITE FOR RESIDUE HEM K1002 |
| Chain | Residue |
| K | TYR39 |
| K | PHE57 |
| K | GLN60 |
| K | TYR64 |
| K | GLY186 |
| K | CYS187 |
| K | CYS190 |
| K | HIS191 |
| K | MET196 |
| K | LEU198 |
| K | ARG221 |
| K | ARG225 |
| K | VAL228 |
| K | MET321 |
| K | TYR323 |
| K | ILE332 |
| K | SER333 |
| K | HIS335 |
| K | TRP337 |
| K | HEC1003 |
| K | HOH2099 |
| L | ALA157 |
| site_id | IC8 |
| Number of Residues | 27 |
| Details | BINDING SITE FOR RESIDUE HEM K1003 |
| Chain | Residue |
| K | GLY78 |
| K | SER79 |
| K | ALA118 |
| K | ARG119 |
| K | GLY120 |
| K | HIS121 |
| K | TYR123 |
| K | ALA124 |
| K | ASP127 |
| K | CYS150 |
| K | LYS151 |
| K | ILE185 |
| K | THR189 |
| K | VAL228 |
| K | CYS229 |
| K | CYS232 |
| K | HIS233 |
| K | HIS320 |
| K | MET321 |
| K | TRP337 |
| K | THR338 |
| K | HEC1001 |
| K | HEC1002 |
| K | HEC1004 |
| K | CA1007 |
| K | HOH2100 |
| K | HOH2101 |
| site_id | IC9 |
| Number of Residues | 24 |
| Details | BINDING SITE FOR RESIDUE HEM K1004 |
| Chain | Residue |
| K | THR74 |
| K | LYS77 |
| K | GLY78 |
| K | GLU117 |
| K | CYS229 |
| K | HIS233 |
| K | TRP304 |
| K | HIS309 |
| K | VAL314 |
| K | THR315 |
| K | CYS316 |
| K | CYS319 |
| K | HIS320 |
| K | SER339 |
| K | MET341 |
| K | GLN369 |
| K | ASN429 |
| K | PHE433 |
| K | HIS434 |
| K | HEC1003 |
| K | HEC1005 |
| K | CA1007 |
| K | HOH2068 |
| K | HOH2102 |
| site_id | JC1 |
| Number of Residues | 23 |
| Details | BINDING SITE FOR RESIDUE HEM K1005 |
| Chain | Residue |
| J | HIS353 |
| J | LYS356 |
| J | HEC1005 |
| J | HOH2112 |
| K | HIS309 |
| K | VAL314 |
| K | ASP318 |
| K | CYS319 |
| K | PRO340 |
| K | ALA348 |
| K | CYS349 |
| K | CYS352 |
| K | HIS353 |
| K | ARG364 |
| K | VAL365 |
| K | PRO436 |
| K | HEC1004 |
| K | HOH2103 |
| K | HOH2104 |
| K | HOH2105 |
| K | HOH2106 |
| L | MET148 |
| L | LYS149 |
| site_id | JC2 |
| Number of Residues | 20 |
| Details | BINDING SITE FOR RESIDUE HEM L1002 |
| Chain | Residue |
| L | ARG40 |
| L | CYS43 |
| L | MET49 |
| L | VAL52 |
| L | HIS56 |
| L | HIS61 |
| L | CYS66 |
| L | CYS69 |
| L | HIS70 |
| L | ILE102 |
| L | ALA104 |
| L | LYS109 |
| L | VAL112 |
| L | THR137 |
| L | VAL143 |
| L | GLN144 |
| L | HIS145 |
| L | HEC1101 |
| L | HOH2012 |
| L | HOH2040 |
| site_id | JC3 |
| Number of Residues | 22 |
| Details | BINDING SITE FOR RESIDUE HEM L1003 |
| Chain | Residue |
| G | LYS329 |
| I | CYS119 |
| I | HIS120 |
| I | MET122 |
| I | THR123 |
| I | ACT1006 |
| L | GLY60 |
| L | HIS61 |
| L | ILE64 |
| L | ASP68 |
| L | CYS69 |
| L | VAL112 |
| L | ASN115 |
| L | CYS116 |
| L | CYS119 |
| L | HIS120 |
| L | HIS140 |
| L | VAL143 |
| L | HEC1004 |
| L | HOH2041 |
| L | HOH2042 |
| L | HOH2043 |
| site_id | JC4 |
| Number of Residues | 19 |
| Details | BINDING SITE FOR RESIDUE HEM L1004 |
| Chain | Residue |
| G | ARG325 |
| G | LYS329 |
| I | HEC1004 |
| I | ACT1006 |
| J | TYR323 |
| J | THR324 |
| J | ARG325 |
| J | LYS331 |
| J | ARG347 |
| J | GLN351 |
| L | CYS116 |
| L | HIS120 |
| L | ASN124 |
| L | SER129 |
| L | LYS133 |
| L | CYS136 |
| L | CYS139 |
| L | HIS140 |
| L | HEC1003 |
| site_id | JC5 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE LMT L1005 |
| Chain | Residue |
| I | LYS35 |
| J | GLY26 |
| J | SER28 |
| J | ASP29 |
| J | VAL30 |
| L | HIS73 |
| L | ASN74 |
| L | LEU75 |
| L | LEU76 |
| site_id | JC6 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE HEM L1101 |
| Chain | Residue |
| L | THR37 |
| L | CYS43 |
| L | CYS46 |
| L | MET49 |
| L | ASN67 |
| L | HIS70 |
| L | ASP89 |
| L | PRO98 |
| L | ALA104 |
| L | GLY105 |
| L | THR108 |
| L | HEC1002 |
| site_id | JC7 |
| Number of Residues | 19 |
| Details | BINDING SITE FOR RESIDUE HEM M1001 |
| Chain | Residue |
| M | TYR115 |
| M | ARG116 |
| M | ALA118 |
| M | PHE128 |
| M | ILE131 |
| M | ARG133 |
| M | CYS147 |
| M | CYS150 |
| M | LYS151 |
| M | CYS232 |
| M | HIS233 |
| M | TYR236 |
| M | HIS298 |
| M | ASN429 |
| M | HEC1003 |
| M | HOH2044 |
| M | HOH2045 |
| M | HOH2193 |
| M | HOH2194 |
| site_id | JC8 |
| Number of Residues | 22 |
| Details | BINDING SITE FOR RESIDUE HEM M1002 |
| Chain | Residue |
| M | TYR39 |
| M | PHE57 |
| M | GLN60 |
| M | TYR61 |
| M | TYR64 |
| M | GLY186 |
| M | CYS187 |
| M | CYS190 |
| M | HIS191 |
| M | MET196 |
| M | LEU198 |
| M | ARG221 |
| M | ARG225 |
| M | MET321 |
| M | SER333 |
| M | HIS335 |
| M | TRP337 |
| M | HEC1003 |
| M | HOH2116 |
| M | HOH2195 |
| M | HOH2196 |
| O | VAL127 |
| site_id | JC9 |
| Number of Residues | 25 |
| Details | BINDING SITE FOR RESIDUE HEM M1003 |
| Chain | Residue |
| M | GLY78 |
| M | SER79 |
| M | ALA118 |
| M | ARG119 |
| M | GLY120 |
| M | HIS121 |
| M | TYR123 |
| M | ALA124 |
| M | ASP127 |
| M | CYS150 |
| M | ILE185 |
| M | THR189 |
| M | VAL228 |
| M | CYS229 |
| M | CYS232 |
| M | HIS233 |
| M | HIS320 |
| M | TRP337 |
| M | THR338 |
| M | HEC1001 |
| M | HEC1002 |
| M | HEC1004 |
| M | CA1007 |
| M | HOH2046 |
| M | HOH2197 |
| site_id | KC1 |
| Number of Residues | 24 |
| Details | BINDING SITE FOR RESIDUE HEM M1004 |
| Chain | Residue |
| M | THR74 |
| M | LYS77 |
| M | GLY78 |
| M | GLU117 |
| M | HIS233 |
| M | GLU300 |
| M | TYR301 |
| M | TRP304 |
| M | HIS309 |
| M | THR315 |
| M | CYS316 |
| M | CYS319 |
| M | HIS320 |
| M | SER339 |
| M | MET341 |
| M | GLN369 |
| M | ASN429 |
| M | PHE433 |
| M | HIS434 |
| M | HEC1003 |
| M | CA1007 |
| M | HOH2198 |
| M | HOH2199 |
| M | HOH2200 |
| site_id | KC2 |
| Number of Residues | 23 |
| Details | BINDING SITE FOR RESIDUE HEM M1005 |
| Chain | Residue |
| M | THR308 |
| M | HIS309 |
| M | ALA312 |
| M | VAL314 |
| M | ASP318 |
| M | CYS319 |
| M | PRO340 |
| M | ALA348 |
| M | CYS349 |
| M | CYS352 |
| M | HIS353 |
| M | ARG364 |
| M | VAL365 |
| M | HOH2137 |
| M | HOH2201 |
| M | HOH2202 |
| M | HOH2203 |
| N | HIS353 |
| N | LYS356 |
| N | HEC1005 |
| N | HOH2139 |
| O | ARG141 |
| O | MET148 |
| site_id | KC3 |
| Number of Residues | 20 |
| Details | BINDING SITE FOR RESIDUE HEM N1001 |
| Chain | Residue |
| N | TYR115 |
| N | ARG116 |
| N | ALA118 |
| N | PHE128 |
| N | ILE131 |
| N | ARG133 |
| N | CYS147 |
| N | CYS150 |
| N | LYS151 |
| N | CYS232 |
| N | HIS233 |
| N | TYR236 |
| N | HIS298 |
| N | ASN429 |
| N | HEC1003 |
| N | HOH2042 |
| N | HOH2060 |
| N | HOH2198 |
| N | HOH2199 |
| N | HOH2200 |
| site_id | KC4 |
| Number of Residues | 21 |
| Details | BINDING SITE FOR RESIDUE HEM N1002 |
| Chain | Residue |
| N | TYR39 |
| N | PHE57 |
| N | GLN60 |
| N | TYR64 |
| N | GLY186 |
| N | CYS187 |
| N | CYS190 |
| N | HIS191 |
| N | MET196 |
| N | LEU198 |
| N | ARG221 |
| N | ARG225 |
| N | MET321 |
| N | TYR323 |
| N | ILE332 |
| N | SER333 |
| N | HIS335 |
| N | TRP337 |
| N | HEC1003 |
| N | HOH2125 |
| O | ALA157 |
| site_id | KC5 |
| Number of Residues | 27 |
| Details | BINDING SITE FOR RESIDUE HEM N1003 |
| Chain | Residue |
| N | GLY78 |
| N | SER79 |
| N | ALA118 |
| N | ARG119 |
| N | HIS121 |
| N | TYR123 |
| N | ALA124 |
| N | ASP127 |
| N | CYS150 |
| N | LYS151 |
| N | ILE185 |
| N | THR189 |
| N | VAL228 |
| N | CYS229 |
| N | CYS232 |
| N | HIS233 |
| N | HIS320 |
| N | TRP337 |
| N | THR338 |
| N | HEC1001 |
| N | HEC1002 |
| N | HEC1004 |
| N | CA1007 |
| N | HOH2020 |
| N | HOH2044 |
| N | HOH2072 |
| N | HOH2201 |
| site_id | KC6 |
| Number of Residues | 25 |
| Details | BINDING SITE FOR RESIDUE HEM N1004 |
| Chain | Residue |
| N | THR74 |
| N | LYS77 |
| N | GLY78 |
| N | GLU117 |
| N | HIS233 |
| N | TYR301 |
| N | TRP304 |
| N | HIS309 |
| N | VAL314 |
| N | THR315 |
| N | CYS316 |
| N | CYS319 |
| N | HIS320 |
| N | SER339 |
| N | PRO340 |
| N | MET341 |
| N | GLN369 |
| N | ASN429 |
| N | PHE433 |
| N | HIS434 |
| N | HEC1003 |
| N | HEC1005 |
| N | CA1007 |
| N | HOH2201 |
| N | HOH2202 |
| site_id | KC7 |
| Number of Residues | 22 |
| Details | BINDING SITE FOR RESIDUE HEM N1005 |
| Chain | Residue |
| M | THR308 |
| M | HIS353 |
| M | LYS356 |
| M | HEC1005 |
| N | HIS309 |
| N | VAL314 |
| N | ASP318 |
| N | CYS319 |
| N | PRO340 |
| N | ALA348 |
| N | CYS349 |
| N | CYS352 |
| N | HIS353 |
| N | ARG364 |
| N | VAL365 |
| N | HEC1004 |
| N | HOH2203 |
| N | HOH2204 |
| N | HOH2205 |
| N | HOH2206 |
| O | MET148 |
| O | LYS149 |
| site_id | KC8 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE HEM O1001 |
| Chain | Residue |
| O | THR37 |
| O | CYS43 |
| O | CYS46 |
| O | ILE48 |
| O | MET49 |
| O | ASN67 |
| O | HIS70 |
| O | ASP89 |
| O | VAL90 |
| O | MET92 |
| O | ASN93 |
| O | PRO98 |
| O | LEU103 |
| O | ALA104 |
| O | GLY105 |
| O | THR108 |
| O | HEC1002 |
| site_id | KC9 |
| Number of Residues | 20 |
| Details | BINDING SITE FOR RESIDUE HEM O1002 |
| Chain | Residue |
| O | CYS43 |
| O | MET49 |
| O | VAL52 |
| O | HIS56 |
| O | HIS61 |
| O | SER65 |
| O | CYS66 |
| O | CYS69 |
| O | HIS70 |
| O | ALA104 |
| O | LYS109 |
| O | VAL112 |
| O | THR137 |
| O | VAL143 |
| O | GLN144 |
| O | HIS145 |
| O | HEC1001 |
| O | HOH2022 |
| O | HOH2040 |
| O | HOH2049 |
| site_id | LC1 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE HEM O1003 |
| Chain | Residue |
| O | GLY60 |
| O | HIS61 |
| O | ASP68 |
| O | VAL112 |
| O | ASN115 |
| O | CYS116 |
| O | CYS119 |
| O | HIS120 |
| O | HIS140 |
| O | HEC1004 |
| O | ACT1006 |
| O | HOH2011 |
| O | HOH2050 |
| P | LYS329 |
| R | CYS119 |
| R | HIS120 |
| R | MET122 |
| R | THR123 |
| site_id | LC2 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE HEM O1004 |
| Chain | Residue |
| M | ASP318 |
| M | TYR323 |
| M | THR324 |
| M | ARG325 |
| M | LYS331 |
| M | GLN351 |
| O | CYS116 |
| O | HIS120 |
| O | ASN124 |
| O | SER129 |
| O | LYS133 |
| O | CYS136 |
| O | CYS139 |
| O | HIS140 |
| O | HEC1003 |
| P | ARG325 |
| P | LYS329 |
| R | HEC1004 |
| site_id | LC3 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE LMT O1005 |
| Chain | Residue |
| M | GLY26 |
| M | SER28 |
| M | ASP29 |
| M | VAL30 |
| O | HIS73 |
| O | ASN74 |
| O | LEU75 |
| O | ALA118 |
| R | LYS35 |
| site_id | LC4 |
| Number of Residues | 20 |
| Details | BINDING SITE FOR RESIDUE HEM P1001 |
| Chain | Residue |
| P | TYR115 |
| P | ARG116 |
| P | ALA118 |
| P | PHE128 |
| P | ILE131 |
| P | ARG133 |
| P | CYS147 |
| P | CYS150 |
| P | LYS151 |
| P | CYS232 |
| P | HIS233 |
| P | TYR236 |
| P | HIS298 |
| P | ASN429 |
| P | HEC1003 |
| P | HOH2044 |
| P | HOH2045 |
| P | HOH2101 |
| P | HOH2166 |
| P | HOH2167 |
| site_id | LC5 |
| Number of Residues | 23 |
| Details | BINDING SITE FOR RESIDUE HEM P1002 |
| Chain | Residue |
| P | TYR39 |
| P | PHE57 |
| P | GLN60 |
| P | TYR61 |
| P | TYR64 |
| P | GLY186 |
| P | CYS187 |
| P | CYS190 |
| P | HIS191 |
| P | MET196 |
| P | LEU198 |
| P | ARG221 |
| P | ARG225 |
| P | MET321 |
| P | ILE332 |
| P | SER333 |
| P | HIS335 |
| P | TRP337 |
| P | HEC1003 |
| P | HOH2110 |
| P | HOH2168 |
| R | VAL127 |
| R | HOH2030 |
| site_id | LC6 |
| Number of Residues | 24 |
| Details | BINDING SITE FOR RESIDUE HEM P1003 |
| Chain | Residue |
| P | GLY78 |
| P | SER79 |
| P | ALA118 |
| P | ARG119 |
| P | GLY120 |
| P | HIS121 |
| P | TYR123 |
| P | ALA124 |
| P | ASP127 |
| P | CYS150 |
| P | ILE185 |
| P | VAL228 |
| P | CYS229 |
| P | CYS232 |
| P | HIS233 |
| P | HIS320 |
| P | MET321 |
| P | TRP337 |
| P | THR338 |
| P | HEC1001 |
| P | HEC1002 |
| P | HEC1004 |
| P | CA1007 |
| P | HOH2027 |
| site_id | LC7 |
| Number of Residues | 24 |
| Details | BINDING SITE FOR RESIDUE HEM P1004 |
| Chain | Residue |
| P | THR74 |
| P | LYS77 |
| P | GLY78 |
| P | GLU117 |
| P | HIS233 |
| P | TYR301 |
| P | TRP304 |
| P | HIS309 |
| P | VAL314 |
| P | THR315 |
| P | CYS316 |
| P | CYS319 |
| P | HIS320 |
| P | SER339 |
| P | MET341 |
| P | GLN369 |
| P | ASN429 |
| P | PHE433 |
| P | HIS434 |
| P | HEC1003 |
| P | HEC1005 |
| P | CA1007 |
| P | HOH2130 |
| P | HOH2169 |
| site_id | LC8 |
| Number of Residues | 22 |
| Details | BINDING SITE FOR RESIDUE HEM P1005 |
| Chain | Residue |
| P | THR308 |
| P | HIS309 |
| P | ALA312 |
| P | CYS319 |
| P | ALA348 |
| P | CYS349 |
| P | CYS352 |
| P | HIS353 |
| P | ARG364 |
| P | VAL365 |
| P | PHE433 |
| P | HEC1004 |
| P | HOH2170 |
| P | HOH2171 |
| P | HOH2172 |
| P | HOH2173 |
| Q | HIS353 |
| Q | LYS356 |
| Q | HEC1005 |
| Q | HOH2081 |
| R | ARG141 |
| R | MET148 |
| site_id | LC9 |
| Number of Residues | 20 |
| Details | BINDING SITE FOR RESIDUE HEM Q1001 |
| Chain | Residue |
| Q | TYR115 |
| Q | ARG116 |
| Q | ALA118 |
| Q | ASP127 |
| Q | PHE128 |
| Q | ARG133 |
| Q | CYS147 |
| Q | CYS150 |
| Q | LYS151 |
| Q | CYS232 |
| Q | HIS233 |
| Q | TYR236 |
| Q | HIS298 |
| Q | ASN429 |
| Q | HEC1003 |
| Q | HOH2029 |
| Q | HOH2121 |
| Q | HOH2122 |
| Q | HOH2123 |
| Q | HOH2124 |
| site_id | MC1 |
| Number of Residues | 22 |
| Details | BINDING SITE FOR RESIDUE HEM Q1002 |
| Chain | Residue |
| Q | TYR39 |
| Q | PHE57 |
| Q | GLN60 |
| Q | TYR61 |
| Q | TYR64 |
| Q | GLY186 |
| Q | CYS187 |
| Q | CYS190 |
| Q | HIS191 |
| Q | MET196 |
| Q | LEU198 |
| Q | ARG221 |
| Q | ARG225 |
| Q | MET321 |
| Q | TYR323 |
| Q | ILE332 |
| Q | SER333 |
| Q | HIS335 |
| Q | TRP337 |
| Q | HEC1003 |
| Q | HOH2069 |
| R | ALA157 |
| site_id | MC2 |
| Number of Residues | 27 |
| Details | BINDING SITE FOR RESIDUE HEM Q1003 |
| Chain | Residue |
| Q | GLY78 |
| Q | SER79 |
| Q | ALA118 |
| Q | ARG119 |
| Q | GLY120 |
| Q | HIS121 |
| Q | TYR123 |
| Q | ALA124 |
| Q | ASP127 |
| Q | CYS150 |
| Q | LYS151 |
| Q | ILE185 |
| Q | THR189 |
| Q | VAL228 |
| Q | CYS229 |
| Q | CYS232 |
| Q | HIS233 |
| Q | HIS320 |
| Q | MET321 |
| Q | TRP337 |
| Q | THR338 |
| Q | HEC1001 |
| Q | HEC1002 |
| Q | HEC1004 |
| Q | CA1007 |
| Q | HOH2006 |
| Q | HOH2125 |
| site_id | MC3 |
| Number of Residues | 26 |
| Details | BINDING SITE FOR RESIDUE HEM Q1004 |
| Chain | Residue |
| Q | THR74 |
| Q | LYS77 |
| Q | GLU117 |
| Q | ALA118 |
| Q | HIS233 |
| Q | GLU300 |
| Q | TRP304 |
| Q | HIS309 |
| Q | VAL314 |
| Q | THR315 |
| Q | CYS316 |
| Q | CYS319 |
| Q | HIS320 |
| Q | SER339 |
| Q | PRO340 |
| Q | MET341 |
| Q | GLN369 |
| Q | ASN429 |
| Q | SER430 |
| Q | PHE433 |
| Q | HIS434 |
| Q | HEC1003 |
| Q | HEC1005 |
| Q | CA1007 |
| Q | HOH2087 |
| Q | HOH2127 |
| site_id | MC4 |
| Number of Residues | 26 |
| Details | BINDING SITE FOR RESIDUE HEM Q1005 |
| Chain | Residue |
| P | HIS353 |
| P | LYS356 |
| P | HEC1005 |
| Q | THR308 |
| Q | HIS309 |
| Q | VAL314 |
| Q | ASP318 |
| Q | CYS319 |
| Q | PRO340 |
| Q | ALA348 |
| Q | CYS349 |
| Q | CYS352 |
| Q | HIS353 |
| Q | ARG364 |
| Q | VAL365 |
| Q | PHE433 |
| Q | PRO436 |
| Q | HEC1004 |
| Q | HOH2128 |
| Q | HOH2129 |
| Q | HOH2130 |
| Q | HOH2131 |
| Q | HOH2132 |
| R | ARG141 |
| R | MET148 |
| R | LYS149 |
| site_id | MC5 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE HEM R1001 |
| Chain | Residue |
| R | THR37 |
| R | CYS43 |
| R | CYS46 |
| R | ILE48 |
| R | MET49 |
| R | ASN67 |
| R | HIS70 |
| R | ASP89 |
| R | MET92 |
| R | ILE102 |
| R | ALA104 |
| R | GLY105 |
| R | THR108 |
| R | HEC1002 |
| R | HOH2041 |
| site_id | MC6 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE HEM R1002 |
| Chain | Residue |
| R | MET49 |
| R | VAL52 |
| R | GLY53 |
| R | HIS56 |
| R | HIS61 |
| R | SER65 |
| R | CYS66 |
| R | CYS69 |
| R | HIS70 |
| R | LYS109 |
| R | VAL112 |
| R | THR137 |
| R | VAL143 |
| R | GLN144 |
| R | HIS145 |
| R | HEC1001 |
| R | HOH2042 |
| site_id | MC7 |
| Number of Residues | 20 |
| Details | BINDING SITE FOR RESIDUE HEM R1003 |
| Chain | Residue |
| M | LYS329 |
| O | CYS119 |
| O | HIS120 |
| O | MET122 |
| O | THR123 |
| O | ACT1006 |
| R | GLY60 |
| R | HIS61 |
| R | ILE64 |
| R | ASP68 |
| R | VAL112 |
| R | ASN115 |
| R | CYS116 |
| R | CYS119 |
| R | HIS120 |
| R | HIS140 |
| R | VAL143 |
| R | HOH2011 |
| R | HOH2043 |
| R | HOH2044 |
| site_id | MC8 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE HEM R1004 |
| Chain | Residue |
| M | ARG325 |
| O | HEC1004 |
| O | ACT1006 |
| P | TYR323 |
| P | ARG325 |
| P | LYS331 |
| P | ARG347 |
| P | GLN351 |
| R | CYS116 |
| R | HIS120 |
| R | ASN124 |
| R | SER129 |
| R | LYS133 |
| R | CYS136 |
| R | CYS139 |
| R | HIS140 |
| site_id | MC9 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE LMT R1005 |
| Chain | Residue |
| O | LYS35 |
| P | GLY26 |
| P | SER28 |
| P | ASP29 |
| P | VAL30 |
| R | HIS73 |
| R | ASN74 |
| R | LEU75 |
| R | ALA118 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 72 |
| Details | TOPO_DOM: Cytoplasmic => ECO:0000269|PubMed:17139260, ECO:0000269|PubMed:18597779 |
| Chain | Residue | Details |
| C | SER2-LYS14 | |
| B | ALA118 | |
| B | GLU235 | |
| B | TYR236 | |
| B | LYS295 | |
| B | GLN297 | |
| D | GLY78 | |
| D | GLU117 | |
| D | ALA118 | |
| D | GLU235 | |
| D | TYR236 | |
| F | SER2-LYS14 | |
| D | LYS295 | |
| D | GLN297 | |
| E | GLY78 | |
| E | GLU117 | |
| E | ALA118 | |
| E | GLU235 | |
| E | TYR236 | |
| E | LYS295 | |
| E | GLN297 | |
| G | GLY78 | |
| I | SER2-LYS14 | |
| G | GLU117 | |
| G | ALA118 | |
| G | GLU235 | |
| G | TYR236 | |
| G | LYS295 | |
| G | GLN297 | |
| H | GLY78 | |
| H | GLU117 | |
| H | ALA118 | |
| H | GLU235 | |
| L | SER2-LYS14 | |
| H | TYR236 | |
| H | LYS295 | |
| H | GLN297 | |
| J | GLY78 | |
| J | GLU117 | |
| J | ALA118 | |
| J | GLU235 | |
| J | TYR236 | |
| J | LYS295 | |
| J | GLN297 | |
| O | SER2-LYS14 | |
| K | GLY78 | |
| K | GLU117 | |
| K | ALA118 | |
| K | GLU235 | |
| K | TYR236 | |
| K | LYS295 | |
| K | GLN297 | |
| M | GLY78 | |
| M | GLU117 | |
| M | ALA118 | |
| R | SER2-LYS14 | |
| M | GLU235 | |
| M | TYR236 | |
| M | LYS295 | |
| M | GLN297 | |
| N | GLY78 | |
| N | GLU117 | |
| N | ALA118 | |
| N | GLU235 | |
| N | TYR236 | |
| N | LYS295 | |
| A | GLN297 | |
| N | GLN297 | |
| P | GLY78 | |
| P | GLU117 | |
| P | ALA118 | |
| P | GLU235 | |
| P | TYR236 | |
| P | LYS295 | |
| P | GLN297 | |
| Q | GLY78 | |
| Q | GLU117 | |
| B | GLY78 | |
| Q | ALA118 | |
| Q | GLU235 | |
| Q | TYR236 | |
| Q | LYS295 | |
| Q | GLN297 | |
| B | GLU117 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 108 |
| Details | TRANSMEM: Helical; Signal-anchor for type II membrane protein => ECO:0000255, ECO:0000269|PubMed:17139260, ECO:0000269|PubMed:18597779 |
| Chain | Residue | Details |
| C | LEU15-GLY33 | |
| B | HIS121 | |
| Q | HIS121 | |
| Q | LYS151 | |
| Q | HIS191 | |
| Q | HIS233 | |
| Q | HIS309 | |
| Q | HIS320 | |
| Q | HIS335 | |
| Q | HIS353 | |
| Q | HIS434 | |
| B | LYS151 | |
| B | HIS191 | |
| B | HIS233 | |
| B | HIS309 | |
| B | HIS320 | |
| B | HIS335 | |
| B | HIS353 | |
| B | HIS434 | |
| D | HIS121 | |
| F | LEU15-GLY33 | |
| D | LYS151 | |
| D | HIS191 | |
| D | HIS233 | |
| D | HIS309 | |
| D | HIS320 | |
| D | HIS335 | |
| D | HIS353 | |
| D | HIS434 | |
| E | HIS121 | |
| E | LYS151 | |
| I | LEU15-GLY33 | |
| E | HIS191 | |
| E | HIS233 | |
| E | HIS309 | |
| E | HIS320 | |
| E | HIS335 | |
| E | HIS353 | |
| E | HIS434 | |
| G | HIS121 | |
| G | LYS151 | |
| G | HIS191 | |
| L | LEU15-GLY33 | |
| G | HIS233 | |
| G | HIS309 | |
| G | HIS320 | |
| G | HIS335 | |
| G | HIS353 | |
| G | HIS434 | |
| H | HIS121 | |
| H | LYS151 | |
| H | HIS191 | |
| H | HIS233 | |
| O | LEU15-GLY33 | |
| H | HIS309 | |
| H | HIS320 | |
| H | HIS335 | |
| H | HIS353 | |
| H | HIS434 | |
| J | HIS121 | |
| J | LYS151 | |
| J | HIS191 | |
| J | HIS233 | |
| J | HIS309 | |
| R | LEU15-GLY33 | |
| J | HIS320 | |
| J | HIS335 | |
| J | HIS353 | |
| J | HIS434 | |
| K | HIS121 | |
| K | LYS151 | |
| K | HIS191 | |
| K | HIS233 | |
| K | HIS309 | |
| K | HIS320 | |
| A | HIS335 | |
| K | HIS335 | |
| K | HIS353 | |
| K | HIS434 | |
| M | HIS121 | |
| M | LYS151 | |
| M | HIS191 | |
| M | HIS233 | |
| M | HIS309 | |
| M | HIS320 | |
| M | HIS335 | |
| A | HIS353 | |
| M | HIS353 | |
| M | HIS434 | |
| N | HIS121 | |
| N | LYS151 | |
| N | HIS191 | |
| N | HIS233 | |
| N | HIS309 | |
| N | HIS320 | |
| N | HIS335 | |
| N | HIS353 | |
| A | HIS434 | |
| N | HIS434 | |
| P | HIS121 | |
| P | LYS151 | |
| P | HIS191 | |
| P | HIS233 | |
| P | HIS309 | |
| P | HIS320 | |
| P | HIS335 | |
| P | HIS353 | |
| P | HIS434 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 750 |
| Details | TOPO_DOM: Periplasmic => ECO:0000269|PubMed:17139260, ECO:0000269|PubMed:18597779 |
| Chain | Residue | Details |
| C | MET34-GLU159 | |
| D | CYS187 | |
| D | CYS232 | |
| D | CYS319 | |
| E | CYS147 | |
| E | CYS187 | |
| E | CYS232 | |
| E | CYS319 | |
| G | CYS147 | |
| G | CYS187 | |
| G | CYS232 | |
| F | MET34-GLU159 | |
| G | CYS319 | |
| H | CYS147 | |
| H | CYS187 | |
| H | CYS232 | |
| H | CYS319 | |
| J | CYS147 | |
| J | CYS187 | |
| J | CYS232 | |
| J | CYS319 | |
| K | CYS147 | |
| I | MET34-GLU159 | |
| K | CYS187 | |
| K | CYS232 | |
| K | CYS319 | |
| M | CYS147 | |
| M | CYS187 | |
| M | CYS232 | |
| M | CYS319 | |
| N | CYS147 | |
| N | CYS187 | |
| N | CYS232 | |
| L | MET34-GLU159 | |
| N | CYS319 | |
| P | CYS147 | |
| P | CYS187 | |
| P | CYS232 | |
| P | CYS319 | |
| Q | CYS147 | |
| Q | CYS187 | |
| Q | CYS232 | |
| Q | CYS319 | |
| O | MET34-GLU159 | |
| R | MET34-GLU159 | |
| B | CYS232 | |
| B | CYS319 | |
| D | CYS147 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 24 |
| Details | BINDING: covalent => ECO:0000269|PubMed:17139260, ECO:0000269|PubMed:18597779, ECO:0007744|PDB:2J7A, ECO:0007744|PDB:2VR0 |
| Chain | Residue | Details |
| C | CYS43 | |
| I | CYS66 | |
| I | CYS69 | |
| I | CYS136 | |
| L | CYS43 | |
| L | CYS66 | |
| L | CYS69 | |
| L | CYS136 | |
| O | CYS43 | |
| O | CYS66 | |
| O | CYS69 | |
| C | CYS66 | |
| O | CYS136 | |
| R | CYS43 | |
| R | CYS66 | |
| R | CYS69 | |
| R | CYS136 | |
| G | CYS352 | |
| H | CYS150 | |
| H | CYS229 | |
| H | CYS316 | |
| H | CYS349 | |
| C | CYS69 | |
| H | CYS352 | |
| J | CYS150 | |
| J | CYS229 | |
| J | CYS316 | |
| J | CYS349 | |
| J | CYS352 | |
| K | CYS150 | |
| K | CYS229 | |
| K | CYS316 | |
| K | CYS349 | |
| C | CYS136 | |
| K | CYS352 | |
| M | CYS150 | |
| M | CYS229 | |
| M | CYS316 | |
| M | CYS349 | |
| M | CYS352 | |
| N | CYS150 | |
| N | CYS229 | |
| N | CYS316 | |
| N | CYS349 | |
| F | CYS43 | |
| N | CYS352 | |
| P | CYS150 | |
| P | CYS229 | |
| P | CYS316 | |
| P | CYS349 | |
| P | CYS352 | |
| Q | CYS150 | |
| Q | CYS229 | |
| Q | CYS316 | |
| Q | CYS349 | |
| F | CYS66 | |
| Q | CYS352 | |
| F | CYS69 | |
| F | CYS136 | |
| I | CYS43 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 24 |
| Details | BINDING: covalent => ECO:0000269|PubMed:17139260, ECO:0007744|PDB:2J7A |
| Chain | Residue | Details |
| C | CYS46 | |
| I | CYS116 | |
| I | CYS119 | |
| I | CYS139 | |
| L | CYS46 | |
| L | CYS116 | |
| L | CYS119 | |
| L | CYS139 | |
| O | CYS46 | |
| O | CYS116 | |
| O | CYS119 | |
| C | CYS116 | |
| O | CYS139 | |
| R | CYS46 | |
| R | CYS116 | |
| R | CYS119 | |
| R | CYS139 | |
| C | CYS119 | |
| C | CYS139 | |
| F | CYS46 | |
| F | CYS116 | |
| F | CYS119 | |
| F | CYS139 | |
| I | CYS46 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 12 |
| Details | BINDING: axial binding residue => ECO:0000269|PubMed:17139260, ECO:0007744|PDB:2J7A |
| Chain | Residue | Details |
| C | MET49 | |
| O | ASP89 | |
| R | MET49 | |
| R | ASP89 | |
| C | ASP89 | |
| F | MET49 | |
| F | ASP89 | |
| I | MET49 | |
| I | ASP89 | |
| L | MET49 | |
| L | ASP89 | |
| O | MET49 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 30 |
| Details | BINDING: axial binding residue => ECO:0000269|PubMed:17139260, ECO:0000269|PubMed:18597779, ECO:0007744|PDB:2J7A, ECO:0007744|PDB:2VR0 |
| Chain | Residue | Details |
| C | HIS61 | |
| F | HIS145 | |
| I | HIS61 | |
| I | HIS70 | |
| I | HIS120 | |
| I | HIS140 | |
| I | HIS145 | |
| L | HIS61 | |
| L | HIS70 | |
| L | HIS120 | |
| L | HIS140 | |
| C | HIS70 | |
| L | HIS145 | |
| O | HIS61 | |
| O | HIS70 | |
| O | HIS120 | |
| O | HIS140 | |
| O | HIS145 | |
| R | HIS61 | |
| R | HIS70 | |
| R | HIS120 | |
| R | HIS140 | |
| C | HIS120 | |
| R | HIS145 | |
| C | HIS140 | |
| C | HIS145 | |
| F | HIS61 | |
| F | HIS70 | |
| F | HIS120 | |
| F | HIS140 |
| site_id | SWS_FT_FI8 |
| Number of Residues | 12 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:18597779, ECO:0007744|PDB:2VR0 |
| Chain | Residue | Details |
| C | ASN67 | |
| O | LYS82 | |
| R | ASN67 | |
| R | LYS82 | |
| C | LYS82 | |
| F | ASN67 | |
| F | LYS82 | |
| I | ASN67 | |
| I | LYS82 | |
| L | ASN67 | |
| L | LYS82 | |
| O | ASN67 |
| site_id | SWS_FT_FI9 |
| Number of Residues | 18 |
| Details | SITE: Interaction with NrfA => ECO:0000269|PubMed:17139260, ECO:0007744|PDB:2J7A |
| Chain | Residue | Details |
| C | ARG40 | |
| L | ARG40 | |
| L | LYS57 | |
| L | ASN63 | |
| O | ARG40 | |
| O | LYS57 | |
| O | ASN63 | |
| R | ARG40 | |
| R | LYS57 | |
| R | ASN63 | |
| C | LYS57 | |
| C | ASN63 | |
| F | ARG40 | |
| F | LYS57 | |
| F | ASN63 | |
| I | ARG40 | |
| I | LYS57 | |
| I | ASN63 |
