Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

2J7A

Crystal structure of cytochrome c nitrite reductase NrfHA complex from Desulfovibrio vulgaris

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005886	cellular_component	plasma membrane
A	0016491	molecular_function	oxidoreductase activity
A	0019645	biological_process	anaerobic electron transport chain
A	0020037	molecular_function	heme binding
A	0030288	cellular_component	outer membrane-bounded periplasmic space
A	0042279	molecular_function	nitrite reductase (cytochrome, ammonia-forming) activity
A	0042597	cellular_component	periplasmic space
A	0046872	molecular_function	metal ion binding
B	0005886	cellular_component	plasma membrane
B	0016491	molecular_function	oxidoreductase activity
B	0019645	biological_process	anaerobic electron transport chain
B	0020037	molecular_function	heme binding
B	0030288	cellular_component	outer membrane-bounded periplasmic space
B	0042279	molecular_function	nitrite reductase (cytochrome, ammonia-forming) activity
B	0042597	cellular_component	periplasmic space
B	0046872	molecular_function	metal ion binding
C	0005886	cellular_component	plasma membrane
C	0009055	molecular_function	electron transfer activity
C	0009061	biological_process	anaerobic respiration
C	0016020	cellular_component	membrane
C	0019333	biological_process	denitrification pathway
C	0020037	molecular_function	heme binding
C	0046872	molecular_function	metal ion binding
D	0005886	cellular_component	plasma membrane
D	0016491	molecular_function	oxidoreductase activity
D	0019645	biological_process	anaerobic electron transport chain
D	0020037	molecular_function	heme binding
D	0030288	cellular_component	outer membrane-bounded periplasmic space
D	0042279	molecular_function	nitrite reductase (cytochrome, ammonia-forming) activity
D	0042597	cellular_component	periplasmic space
D	0046872	molecular_function	metal ion binding
E	0005886	cellular_component	plasma membrane
E	0016491	molecular_function	oxidoreductase activity
E	0019645	biological_process	anaerobic electron transport chain
E	0020037	molecular_function	heme binding
E	0030288	cellular_component	outer membrane-bounded periplasmic space
E	0042279	molecular_function	nitrite reductase (cytochrome, ammonia-forming) activity
E	0042597	cellular_component	periplasmic space
E	0046872	molecular_function	metal ion binding
F	0005886	cellular_component	plasma membrane
F	0009055	molecular_function	electron transfer activity
F	0009061	biological_process	anaerobic respiration
F	0016020	cellular_component	membrane
F	0019333	biological_process	denitrification pathway
F	0020037	molecular_function	heme binding
F	0046872	molecular_function	metal ion binding
G	0005886	cellular_component	plasma membrane
G	0016491	molecular_function	oxidoreductase activity
G	0019645	biological_process	anaerobic electron transport chain
G	0020037	molecular_function	heme binding
G	0030288	cellular_component	outer membrane-bounded periplasmic space
G	0042279	molecular_function	nitrite reductase (cytochrome, ammonia-forming) activity
G	0042597	cellular_component	periplasmic space
G	0046872	molecular_function	metal ion binding
H	0005886	cellular_component	plasma membrane
H	0016491	molecular_function	oxidoreductase activity
H	0019645	biological_process	anaerobic electron transport chain
H	0020037	molecular_function	heme binding
H	0030288	cellular_component	outer membrane-bounded periplasmic space
H	0042279	molecular_function	nitrite reductase (cytochrome, ammonia-forming) activity
H	0042597	cellular_component	periplasmic space
H	0046872	molecular_function	metal ion binding
I	0005886	cellular_component	plasma membrane
I	0009055	molecular_function	electron transfer activity
I	0009061	biological_process	anaerobic respiration
I	0016020	cellular_component	membrane
I	0019333	biological_process	denitrification pathway
I	0020037	molecular_function	heme binding
I	0046872	molecular_function	metal ion binding
J	0005886	cellular_component	plasma membrane
J	0016491	molecular_function	oxidoreductase activity
J	0019645	biological_process	anaerobic electron transport chain
J	0020037	molecular_function	heme binding
J	0030288	cellular_component	outer membrane-bounded periplasmic space
J	0042279	molecular_function	nitrite reductase (cytochrome, ammonia-forming) activity
J	0042597	cellular_component	periplasmic space
J	0046872	molecular_function	metal ion binding
K	0005886	cellular_component	plasma membrane
K	0016491	molecular_function	oxidoreductase activity
K	0019645	biological_process	anaerobic electron transport chain
K	0020037	molecular_function	heme binding
K	0030288	cellular_component	outer membrane-bounded periplasmic space
K	0042279	molecular_function	nitrite reductase (cytochrome, ammonia-forming) activity
K	0042597	cellular_component	periplasmic space
K	0046872	molecular_function	metal ion binding
L	0005886	cellular_component	plasma membrane
L	0009055	molecular_function	electron transfer activity
L	0009061	biological_process	anaerobic respiration
L	0016020	cellular_component	membrane
L	0019333	biological_process	denitrification pathway
L	0020037	molecular_function	heme binding
L	0046872	molecular_function	metal ion binding
M	0005886	cellular_component	plasma membrane
M	0016491	molecular_function	oxidoreductase activity
M	0019645	biological_process	anaerobic electron transport chain
M	0020037	molecular_function	heme binding
M	0030288	cellular_component	outer membrane-bounded periplasmic space
M	0042279	molecular_function	nitrite reductase (cytochrome, ammonia-forming) activity
M	0042597	cellular_component	periplasmic space
M	0046872	molecular_function	metal ion binding
N	0005886	cellular_component	plasma membrane
N	0016491	molecular_function	oxidoreductase activity
N	0019645	biological_process	anaerobic electron transport chain
N	0020037	molecular_function	heme binding
N	0030288	cellular_component	outer membrane-bounded periplasmic space
N	0042279	molecular_function	nitrite reductase (cytochrome, ammonia-forming) activity
N	0042597	cellular_component	periplasmic space
N	0046872	molecular_function	metal ion binding
O	0005886	cellular_component	plasma membrane
O	0009055	molecular_function	electron transfer activity
O	0009061	biological_process	anaerobic respiration
O	0016020	cellular_component	membrane
O	0019333	biological_process	denitrification pathway
O	0020037	molecular_function	heme binding
O	0046872	molecular_function	metal ion binding
P	0005886	cellular_component	plasma membrane
P	0016491	molecular_function	oxidoreductase activity
P	0019645	biological_process	anaerobic electron transport chain
P	0020037	molecular_function	heme binding
P	0030288	cellular_component	outer membrane-bounded periplasmic space
P	0042279	molecular_function	nitrite reductase (cytochrome, ammonia-forming) activity
P	0042597	cellular_component	periplasmic space
P	0046872	molecular_function	metal ion binding
Q	0005886	cellular_component	plasma membrane
Q	0016491	molecular_function	oxidoreductase activity
Q	0019645	biological_process	anaerobic electron transport chain
Q	0020037	molecular_function	heme binding
Q	0030288	cellular_component	outer membrane-bounded periplasmic space
Q	0042279	molecular_function	nitrite reductase (cytochrome, ammonia-forming) activity
Q	0042597	cellular_component	periplasmic space
Q	0046872	molecular_function	metal ion binding
R	0005886	cellular_component	plasma membrane
R	0009055	molecular_function	electron transfer activity
R	0009061	biological_process	anaerobic respiration
R	0016020	cellular_component	membrane
R	0019333	biological_process	denitrification pathway
R	0020037	molecular_function	heme binding
R	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA A1006

Chain	Residue
A	GLU235
A	TYR236
A	LYS295
A	GLN297
A	HOH2098
A	HOH2101

site_id	AC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA A1007

Chain	Residue
A	HEC1003
A	HEC1004
A	HOH2195
A	GLY78
A	GLU117
A	ALA118

site_id	AC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA B1006

Chain	Residue
B	GLU235
B	TYR236
B	LYS295
B	GLN297
B	HOH2101
B	HOH2105

site_id	AC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CA B1007

Chain	Residue
B	GLY78
B	GLU117
B	ALA118
B	HEC1003
B	HEC1004

site_id	AC5
Number of Residues	5
Details	BINDING SITE FOR RESIDUE ACT C1006

Chain	Residue
A	HOH2118
C	HIS120
C	HEC1003
F	HEC1003
F	HEC1004

site_id	AC6
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA D1006

Chain	Residue
D	GLU235
D	TYR236
D	LYS295
D	GLN297
D	HOH2092
D	HOH2095

site_id	AC7
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CA D1007

Chain	Residue
D	GLY78
D	GLU117
D	ALA118
D	HEC1003
D	HEC1004

site_id	AC8
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CA E1006

Chain	Residue
E	GLU235
E	TYR236
E	LYS295
E	GLN297
E	HOH2085

site_id	AC9
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CA E1007

Chain	Residue
E	GLY78
E	GLU117
E	ALA118
E	HEC1003
E	HEC1004

site_id	BC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA G1006

Chain	Residue
G	GLU235
G	TYR236
G	LYS295
G	GLN297
G	HOH2074
G	HOH2080

site_id	BC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA G1007

Chain	Residue
G	GLY78
G	GLU117
G	ALA118
G	HEC1003
G	HEC1004
G	HOH2155

site_id	BC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA H1006

Chain	Residue
H	GLU235
H	TYR236
H	LYS295
H	GLN297
H	HOH2103
H	HOH2104

site_id	BC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CA H1007

Chain	Residue
H	GLY78
H	GLU117
H	ALA118
H	HEC1003
H	HEC1004

site_id	BC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ACT I1006

Chain	Residue
I	HEC1003
I	HEC1004
L	HEC1003
L	HEC1004

site_id	BC6
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA J1006

Chain	Residue
J	GLU235
J	TYR236
J	LYS295
J	GLN297
J	HOH2087
J	HOH2088

site_id	BC7
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA J1007

Chain	Residue
J	GLY78
J	GLU117
J	ALA118
J	HEC1003
J	HEC1004
J	HOH2165

site_id	BC8
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA K1006

Chain	Residue
K	GLU235
K	TYR236
K	LYS295
K	GLN297
K	HOH2043
K	HOH2048

site_id	BC9
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CA K1007

Chain	Residue
K	GLY78
K	GLU117
K	ALA118
K	HEC1003
K	HEC1004

site_id	CC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA M1006

Chain	Residue
M	GLU235
M	TYR236
M	LYS295
M	GLN297
M	HOH2103
M	HOH2104

site_id	CC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA M1007

Chain	Residue
M	GLY78
M	GLU117
M	ALA118
M	HEC1003
M	HEC1004
M	HOH2200

site_id	CC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA N1006

Chain	Residue
N	GLU235
N	TYR236
N	LYS295
N	GLN297
N	HOH2112
N	HOH2113

site_id	CC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CA N1007

Chain	Residue
N	GLY78
N	GLU117
N	ALA118
N	HEC1003
N	HEC1004

site_id	CC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ACT O1006

Chain	Residue
O	HEC1003
P	HOH2111
R	HEC1003
R	HEC1004

site_id	CC6
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA P1006

Chain	Residue
P	GLU235
P	TYR236
P	LYS295
P	GLN297
P	HOH2094
P	HOH2098

site_id	CC7
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CA P1007

Chain	Residue
P	GLY78
P	GLU117
P	ALA118
P	HEC1003
P	HEC1004

site_id	CC8
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CA Q1006

Chain	Residue
Q	GLU235
Q	TYR236
Q	LYS295
Q	GLN297
Q	HOH2062

site_id	CC9
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CA Q1007

Chain	Residue
Q	GLY78
Q	GLU117
Q	ALA118
Q	HEC1003
Q	HEC1004

site_id	DC1
Number of Residues	20
Details	BINDING SITE FOR RESIDUE HEM A1001

Chain	Residue
A	TYR115
A	ARG116
A	ALA118
A	PHE128
A	ILE131
A	ARG133
A	CYS147
A	CYS150
A	LYS151
A	CYS232
A	HIS233
A	TYR236
A	HIS298
A	ASN429
A	HEC1003
A	HOH2032
A	HOH2034
A	HOH2103
A	HOH2187
A	HOH2188

site_id	DC2
Number of Residues	23
Details	BINDING SITE FOR RESIDUE HEM A1002

Chain	Residue
A	TYR39
A	PHE57
A	GLN60
A	TYR64
A	GLY186
A	CYS187
A	CYS190
A	HIS191
A	MET196
A	LEU198
A	ARG221
A	ARG225
A	MET321
A	ILE332
A	SER333
A	HIS335
A	TRP337
A	HEC1003
A	HOH2117
A	HOH2189
A	HOH2190
A	HOH2191
C	VAL127

site_id	DC3
Number of Residues	25
Details	BINDING SITE FOR RESIDUE HEM A1003

Chain	Residue
A	GLY78
A	SER79
A	ALA118
A	ARG119
A	GLY120
A	HIS121
A	TYR123
A	ALA124
A	ASP127
A	CYS150
A	ILE185
A	THR189
A	VAL228
A	CYS229
A	CYS232
A	HIS233
A	HIS320
A	TRP337
A	THR338
A	HEC1001
A	HEC1002
A	HEC1004
A	CA1007
A	HOH2192
A	HOH2193

site_id	DC4
Number of Residues	24
Details	BINDING SITE FOR RESIDUE HEM A1004

Chain	Residue
A	THR74
A	LYS77
A	GLY78
A	GLU117
A	HIS233
A	TRP304
A	HIS309
A	VAL314
A	THR315
A	CYS316
A	CYS319
A	HIS320
A	SER339
A	PRO340
A	MET341
A	GLN369
A	ASN429
A	PHE433
A	HIS434
A	HEC1003
A	CA1007
A	HOH2194
A	HOH2195
A	HOH2196

site_id	DC5
Number of Residues	20
Details	BINDING SITE FOR RESIDUE HEM A1005

Chain	Residue
A	HIS309
A	VAL314
A	PRO340
A	ALA348
A	CYS349
A	CYS352
A	HIS353
A	ARG364
A	VAL365
A	HOH2197
A	HOH2198
A	HOH2199
A	HOH2200
A	HOH2201
B	HIS353
B	LYS356
B	HEC1005
B	HOH2183
C	ARG141
C	MET148

site_id	DC6
Number of Residues	21
Details	BINDING SITE FOR RESIDUE HEM B1001

Chain	Residue
B	TYR115
B	ARG116
B	ALA118
B	PHE128
B	ILE131
B	ARG133
B	CYS147
B	CYS150
B	LYS151
B	CYS232
B	HIS233
B	TYR236
B	HIS298
B	ASN429
B	HEC1003
B	HOH2031
B	HOH2046
B	HOH2176
B	HOH2177
B	HOH2178
B	HOH2179

site_id	DC7
Number of Residues	21
Details	BINDING SITE FOR RESIDUE HEM B1002

Chain	Residue
B	TYR39
B	PHE57
B	GLN60
B	TYR64
B	GLY186
B	CYS187
B	CYS190
B	HIS191
B	MET196
B	ARG221
B	ARG225
B	MET321
B	TYR323
B	ILE332
B	SER333
B	HIS335
B	TRP337
B	HEC1003
B	HOH2118
B	HOH2180
C	ALA157

site_id	DC8
Number of Residues	25
Details	BINDING SITE FOR RESIDUE HEM B1003

Chain	Residue
B	GLY78
B	SER79
B	ALA118
B	ARG119
B	HIS121
B	TYR123
B	ALA124
B	ASP127
B	CYS150
B	LYS151
B	ILE185
B	THR189
B	VAL228
B	CYS229
B	CYS232
B	HIS233
B	HIS320
B	TRP337
B	THR338
B	HEC1001
B	HEC1002
B	HEC1004
B	CA1007
B	HOH2181
B	HOH2182

site_id	DC9
Number of Residues	23
Details	BINDING SITE FOR RESIDUE HEM B1004

Chain	Residue
B	THR74
B	LYS77
B	GLY78
B	GLU117
B	HIS233
B	TRP304
B	HIS309
B	VAL314
B	THR315
B	CYS316
B	CYS319
B	HIS320
B	SER339
B	PRO340
B	MET341
B	GLN369
B	ASN429
B	PHE433
B	HIS434
B	HEC1003
B	CA1007
B	HOH2137
B	HOH2182

site_id	EC1
Number of Residues	23
Details	BINDING SITE FOR RESIDUE HEM B1005

Chain	Residue
A	THR308
A	HIS353
A	LYS356
A	HEC1005
B	HIS309
B	VAL314
B	ASP318
B	CYS319
B	PRO340
B	ALA348
B	CYS349
B	CYS352
B	HIS353
B	ARG364
B	VAL365
B	HOH2183
B	HOH2184
B	HOH2185
B	HOH2186
B	HOH2187
B	HOH2188
C	MET148
C	LYS149

site_id	EC2
Number of Residues	15
Details	BINDING SITE FOR RESIDUE HEM C1001

Chain	Residue
C	THR37
C	CYS43
C	CYS46
C	ILE48
C	MET49
C	ASN67
C	HIS70
C	ASP89
C	MET92
C	ASN93
C	LEU103
C	ALA104
C	GLY105
C	THR108
C	HEC1002

site_id	EC3
Number of Residues	19
Details	BINDING SITE FOR RESIDUE HEM C1002

Chain	Residue
C	ARG40
C	CYS43
C	MET49
C	VAL52
C	HIS56
C	HIS61
C	SER65
C	CYS66
C	CYS69
C	HIS70
C	ILE102
C	LYS109
C	VAL112
C	THR137
C	GLN144
C	HIS145
C	HEC1001
C	HOH2022
C	HOH2047

site_id	EC4
Number of Residues	20
Details	BINDING SITE FOR RESIDUE HEM C1003

Chain	Residue
C	GLY60
C	HIS61
C	ASP68
C	VAL112
C	ASN115
C	CYS116
C	CYS119
C	HIS120
C	HIS140
C	VAL143
C	HEC1004
C	ACT1006
C	HOH2012
C	HOH2048
C	HOH2049
D	LYS329
F	CYS119
F	HIS120
F	MET122
F	THR123

site_id	EC5
Number of Residues	17
Details	BINDING SITE FOR RESIDUE HEM C1004

Chain	Residue
A	TYR323
A	ARG325
A	LYS331
A	GLN351
A	HOH2119
C	CYS116
C	HIS120
C	ASN124
C	SER129
C	LYS133
C	CYS136
C	CYS139
C	HIS140
C	HEC1003
D	ARG325
D	LYS329
F	HEC1004

site_id	EC6
Number of Residues	9
Details	BINDING SITE FOR RESIDUE LMT C1005

Chain	Residue
A	GLY26
A	SER28
A	ASP29
A	VAL30
C	HIS73
C	ASN74
C	LEU75
C	ALA118
C	HOH2050

site_id	EC7
Number of Residues	20
Details	BINDING SITE FOR RESIDUE HEM D1001

Chain	Residue
D	TYR115
D	ARG116
D	ALA118
D	PHE128
D	ILE131
D	ARG133
D	CYS147
D	CYS150
D	LYS151
D	CYS232
D	HIS233
D	TYR236
D	PHE238
D	HIS298
D	ASN429
D	HEC1003
D	HOH2038
D	HOH2158
D	HOH2159
D	HOH2160

site_id	EC8
Number of Residues	24
Details	BINDING SITE FOR RESIDUE HEM D1002

Chain	Residue
D	TYR39
D	PHE57
D	GLN60
D	TYR61
D	TYR64
D	GLY186
D	CYS187
D	CYS190
D	HIS191
D	MET196
D	LEU198
D	ARG221
D	ARG225
D	MET321
D	ILE332
D	SER333
D	HIS335
D	TRP337
D	HEC1003
D	HOH2108
D	HOH2161
D	HOH2162
F	GLU126
F	VAL127

site_id	EC9
Number of Residues	25
Details	BINDING SITE FOR RESIDUE HEM D1003

Chain	Residue
D	GLY78
D	SER79
D	ALA118
D	ARG119
D	GLY120
D	HIS121
D	TYR123
D	ALA124
D	ASP127
D	CYS150
D	ILE185
D	VAL228
D	CYS229
D	CYS232
D	HIS233
D	HIS320
D	MET321
D	TRP337
D	THR338
D	HEC1001
D	HEC1002
D	HEC1004
D	CA1007
D	HOH2039
D	HOH2163

site_id	FC1
Number of Residues	23
Details	BINDING SITE FOR RESIDUE HEM D1004

Chain	Residue
D	THR74
D	LYS77
D	GLY78
D	GLU117
D	CYS229
D	HIS233
D	TRP304
D	HIS309
D	VAL314
D	THR315
D	CYS316
D	CYS319
D	HIS320
D	SER339
D	MET341
D	GLN369
D	ASN429
D	PHE433
D	HIS434
D	HEC1003
D	CA1007
D	HOH2164
D	HOH2165

site_id	FC2
Number of Residues	17
Details	BINDING SITE FOR RESIDUE HEM D1005

Chain	Residue
D	HIS309
D	VAL314
D	ALA348
D	CYS349
D	CYS352
D	HIS353
D	ARG364
D	VAL365
D	HOH2125
D	HOH2166
D	HOH2167
D	HOH2168
D	HOH2169
D	HOH2170
E	HIS353
E	LYS356
F	ARG141

site_id	FC3
Number of Residues	21
Details	BINDING SITE FOR RESIDUE HEM E1001

Chain	Residue
E	TYR115
E	ARG116
E	ALA118
E	PHE128
E	ILE131
E	ARG133
E	CYS147
E	CYS150
E	LYS151
E	CYS232
E	HIS233
E	TYR236
E	HIS298
E	ASN429
E	HEC1003
E	HOH2045
E	HOH2049
E	HOH2070
E	HOH2149
E	HOH2150
E	HOH2151

site_id	FC4
Number of Residues	22
Details	BINDING SITE FOR RESIDUE HEM E1002

Chain	Residue
E	TYR39
E	PHE57
E	GLN60
E	TYR61
E	TYR64
E	GLY186
E	CYS187
E	CYS190
E	HIS191
E	MET196
E	LEU198
E	ARG221
E	ARG225
E	MET321
E	TYR323
E	ILE332
E	SER333
E	HIS335
E	TRP337
E	HEC1003
E	HOH2099
F	ALA157

site_id	FC5
Number of Residues	27
Details	BINDING SITE FOR RESIDUE HEM E1003

Chain	Residue
E	GLY78
E	SER79
E	ALA118
E	ARG119
E	GLY120
E	HIS121
E	TYR123
E	ALA124
E	ASP127
E	CYS150
E	LYS151
E	ILE185
E	THR189
E	VAL228
E	CYS229
E	CYS232
E	HIS233
E	HIS320
E	MET321
E	TRP337
E	THR338
E	HEC1001
E	HEC1002
E	HEC1004
E	CA1007
E	HOH2039
E	HOH2152

site_id	FC6
Number of Residues	22
Details	BINDING SITE FOR RESIDUE HEM E1004

Chain	Residue
E	THR74
E	LYS77
E	GLY78
E	GLU117
E	HIS233
E	TRP304
E	HIS309
E	VAL314
E	THR315
E	CYS316
E	CYS319
E	HIS320
E	SER339
E	MET341
E	GLN369
E	ASN429
E	PHE433
E	HIS434
E	HEC1003
E	HEC1005
E	CA1007
E	HOH2153

site_id	FC7
Number of Residues	19
Details	BINDING SITE FOR RESIDUE HEM E1005

Chain	Residue
D	HIS353
D	LYS356
D	HOH2167
E	THR308
E	HIS309
E	VAL314
E	ASP318
E	CYS319
E	ALA348
E	CYS349
E	CYS352
E	HIS353
E	ARG364
E	VAL365
E	HEC1004
E	HOH2154
E	HOH2155
F	MET148
F	LYS149

site_id	FC8
Number of Residues	14
Details	BINDING SITE FOR RESIDUE HEM F1001

Chain	Residue
F	THR37
F	CYS43
F	CYS46
F	ILE48
F	MET49
F	ASN67
F	HIS70
F	ASP89
F	MET92
F	PRO98
F	ALA104
F	GLY105
F	THR108
F	HEC1002

site_id	FC9
Number of Residues	18
Details	BINDING SITE FOR RESIDUE HEM F1002

Chain	Residue
F	ARG40
F	MET49
F	VAL52
F	HIS56
F	HIS61
F	SER65
F	CYS66
F	CYS69
F	HIS70
F	LYS109
F	VAL112
F	THR137
F	VAL143
F	GLN144
F	HIS145
F	HEC1001
F	HOH2035
F	HOH2039

site_id	GC1
Number of Residues	19
Details	BINDING SITE FOR RESIDUE HEM F1003

Chain	Residue
A	LYS329
C	CYS119
C	HIS120
C	MET122
C	THR123
C	ACT1006
F	GLY60
F	HIS61
F	ASP68
F	VAL112
F	ASN115
F	CYS116
F	CYS119
F	HIS120
F	HIS140
F	VAL143
F	HOH2040
F	HOH2041
F	HOH2042

site_id	GC2
Number of Residues	16
Details	BINDING SITE FOR RESIDUE HEM F1004

Chain	Residue
A	ARG325
C	HEC1004
C	ACT1006
D	ASP318
D	TYR323
D	THR324
D	ARG325
D	LYS331
D	GLN351
F	CYS116
F	HIS120
F	ASN124
F	SER129
F	CYS136
F	CYS139
F	HIS140

site_id	GC3
Number of Residues	9
Details	BINDING SITE FOR RESIDUE LMT F1005

Chain	Residue
C	LYS35
D	GLY26
D	SER28
D	ASP29
D	VAL30
F	HIS73
F	ASN74
F	LEU75
F	ALA118

site_id	GC4
Number of Residues	20
Details	BINDING SITE FOR RESIDUE HEM G1001

Chain	Residue
G	TYR115
G	ARG116
G	ALA118
G	PHE128
G	ILE131
G	ARG133
G	CYS147
G	CYS150
G	LYS151
G	CYS232
G	HIS233
G	TYR236
G	HIS298
G	ASN429
G	HEC1003
G	HOH2036
G	HOH2047
G	HOH2082
G	HOH2148
G	HOH2149

site_id	GC5
Number of Residues	22
Details	BINDING SITE FOR RESIDUE HEM G1002

Chain	Residue
G	TYR39
G	PHE57
G	GLN60
G	TYR64
G	GLY186
G	CYS187
G	CYS190
G	HIS191
G	MET196
G	LEU198
G	ARG221
G	ARG225
G	MET321
G	SER333
G	HIS335
G	TRP337
G	HEC1003
G	HOH2091
G	HOH2150
G	HOH2151
I	GLU126
I	VAL127

site_id	GC6
Number of Residues	25
Details	BINDING SITE FOR RESIDUE HEM G1003

Chain	Residue
G	GLY78
G	SER79
G	ALA118
G	ARG119
G	GLY120
G	HIS121
G	TYR123
G	ALA124
G	ASP127
G	CYS150
G	ILE185
G	THR189
G	VAL228
G	CYS229
G	CYS232
G	HIS233
G	HIS320
G	TRP337
G	THR338
G	HEC1001
G	HEC1002
G	HEC1004
G	CA1007
G	HOH2037
G	HOH2152

site_id	GC7
Number of Residues	23
Details	BINDING SITE FOR RESIDUE HEM G1004

Chain	Residue
G	THR74
G	LYS77
G	GLY78
G	GLU117
G	HIS233
G	TRP304
G	HIS309
G	VAL314
G	THR315
G	CYS316
G	CYS319
G	HIS320
G	SER339
G	GLN369
G	ASN429
G	PHE433
G	HIS434
G	HEC1003
G	HEC1005
G	CA1007
G	HOH2153
G	HOH2154
G	HOH2155

site_id	GC8
Number of Residues	18
Details	BINDING SITE FOR RESIDUE HEM G1005

Chain	Residue
G	HIS309
G	ALA348
G	CYS349
G	CYS352
G	HIS353
G	ARG364
G	VAL365
G	HEC1004
G	HOH2157
G	HOH2158
G	HOH2159
G	HOH2160
H	HIS353
H	LYS356
H	HEC1005
H	HOH2192
I	ARG141
I	MET148

site_id	GC9
Number of Residues	20
Details	BINDING SITE FOR RESIDUE HEM H1001

Chain	Residue
H	TYR115
H	ARG116
H	ASP127
H	PHE128
H	ILE131
H	ARG133
H	CYS147
H	CYS150
H	LYS151
H	CYS232
H	HIS233
H	TYR236
H	HIS298
H	ASN429
H	HEC1003
H	HOH2031
H	HOH2049
H	HOH2184
H	HOH2185
H	HOH2186

site_id	HC1
Number of Residues	20
Details	BINDING SITE FOR RESIDUE HEM H1002

Chain	Residue
H	TYR39
H	PHE57
H	GLN60
H	TYR64
H	GLY186
H	CYS187
H	CYS190
H	HIS191
H	MET196
H	LEU198
H	ARG221
H	ARG225
H	MET321
H	ILE332
H	SER333
H	HIS335
H	TRP337
H	HEC1003
H	HOH2117
I	ALA157

site_id	HC2
Number of Residues	25
Details	BINDING SITE FOR RESIDUE HEM H1003

Chain	Residue
H	GLY78
H	SER79
H	ALA118
H	ARG119
H	GLY120
H	HIS121
H	TYR123
H	ALA124
H	ASP127
H	CYS150
H	LYS151
H	ILE185
H	THR189
H	VAL228
H	CYS229
H	CYS232
H	HIS233
H	HIS320
H	TRP337
H	THR338
H	HEC1001
H	HEC1002
H	HEC1004
H	CA1007
H	HOH2187

site_id	HC3
Number of Residues	23
Details	BINDING SITE FOR RESIDUE HEM H1004

Chain	Residue
H	THR74
H	LYS77
H	GLY78
H	GLU117
H	GLU300
H	TRP304
H	HIS309
H	VAL314
H	THR315
H	CYS316
H	CYS319
H	HIS320
H	SER339
H	MET341
H	GLN369
H	ASN429
H	PHE433
H	HIS434
H	HEC1003
H	HEC1005
H	CA1007
H	HOH2139
H	HOH2188

site_id	HC4
Number of Residues	24
Details	BINDING SITE FOR RESIDUE HEM H1005

Chain	Residue
G	HIS353
G	LYS356
G	HEC1005
H	HIS309
H	VAL314
H	ASP318
H	CYS319
H	PRO340
H	ALA348
H	CYS349
H	CYS352
H	HIS353
H	ARG364
H	VAL365
H	PRO436
H	HEC1004
H	HOH2189
H	HOH2190
H	HOH2191
H	HOH2192
H	HOH2193
H	HOH2194
I	MET148
I	LYS149

site_id	HC5
Number of Residues	12
Details	BINDING SITE FOR RESIDUE HEM I1001

Chain	Residue
I	THR37
I	CYS43
I	CYS46
I	MET49
I	ASN67
I	HIS70
I	ASP89
I	ASN93
I	ALA104
I	GLY105
I	THR108
I	HEC1002

site_id	HC6
Number of Residues	19
Details	BINDING SITE FOR RESIDUE HEM I1002

Chain	Residue
I	CYS43
I	MET49
I	VAL52
I	HIS56
I	HIS61
I	SER65
I	CYS66
I	CYS69
I	HIS70
I	ILE102
I	ALA104
I	LYS109
I	VAL112
I	THR137
I	GLN144
I	HIS145
I	HEC1001
I	HOH2037
I	HOH2038

site_id	HC7
Number of Residues	19
Details	BINDING SITE FOR RESIDUE HEM I1003

Chain	Residue
I	GLY60
I	HIS61
I	ASP68
I	VAL112
I	ASN115
I	CYS116
I	CYS119
I	HIS120
I	HIS140
I	VAL143
I	HEC1004
I	ACT1006
I	HOH2039
I	HOH2040
J	LYS329
L	CYS119
L	HIS120
L	MET122
L	THR123

site_id	HC8
Number of Residues	18
Details	BINDING SITE FOR RESIDUE HEM I1004

Chain	Residue
G	ASP318
G	TYR323
G	THR324
G	ARG325
G	LYS331
G	GLN351
I	CYS116
I	HIS120
I	ASN124
I	SER129
I	CYS136
I	CYS139
I	HIS140
I	HEC1003
I	ACT1006
J	ARG325
J	LYS329
L	HEC1004

site_id	HC9
Number of Residues	8
Details	BINDING SITE FOR RESIDUE LMT I1005

Chain	Residue
G	GLY26
G	SER28
G	ASP29
G	VAL30
I	HIS73
I	ASN74
I	LEU75
I	ALA118

site_id	IC1
Number of Residues	19
Details	BINDING SITE FOR RESIDUE HEM J1001

Chain	Residue
J	TYR115
J	ARG116
J	PHE128
J	ILE131
J	ARG133
J	CYS147
J	CYS150
J	LYS151
J	CYS232
J	HIS233
J	TYR236
J	HIS298
J	ASN429
J	HEC1003
J	HOH2034
J	HOH2157
J	HOH2158
J	HOH2159
J	HOH2160

site_id	IC2
Number of Residues	25
Details	BINDING SITE FOR RESIDUE HEM J1002

Chain	Residue
J	TYR39
J	PHE57
J	GLN60
J	TYR61
J	TYR64
J	GLY186
J	CYS187
J	CYS190
J	HIS191
J	MET196
J	LEU198
J	ARG221
J	ARG225
J	MET321
J	ILE332
J	SER333
J	HIS335
J	TRP337
J	HEC1003
J	HOH2100
J	HOH2161
J	HOH2162
L	GLU126
L	VAL127
L	HOH2029

site_id	IC3
Number of Residues	26
Details	BINDING SITE FOR RESIDUE HEM J1003

Chain	Residue
J	GLY78
J	SER79
J	ALA118
J	ARG119
J	GLY120
J	HIS121
J	TYR123
J	ALA124
J	ASP127
J	CYS150
J	ILE185
J	THR189
J	VAL228
J	CYS229
J	CYS232
J	HIS233
J	HIS320
J	MET321
J	TRP337
J	THR338
J	HEC1001
J	HEC1002
J	HEC1004
J	CA1007
J	HOH2036
J	HOH2163

site_id	IC4
Number of Residues	26
Details	BINDING SITE FOR RESIDUE HEM J1004

Chain	Residue
J	THR74
J	LYS77
J	GLY78
J	GLU117
J	CYS229
J	HIS233
J	TYR301
J	TRP304
J	HIS309
J	VAL314
J	THR315
J	CYS316
J	CYS319
J	HIS320
J	SER339
J	MET341
J	GLN369
J	ASN429
J	PHE433
J	HIS434
J	HEC1003
J	HEC1005
J	CA1007
J	HOH2118
J	HOH2164
J	HOH2165

site_id	IC5
Number of Residues	19
Details	BINDING SITE FOR RESIDUE HEM J1005

Chain	Residue
J	THR308
J	HIS309
J	ALA312
J	CYS319
J	ALA348
J	CYS349
J	CYS352
J	HIS353
J	ARG364
J	VAL365
J	HEC1004
J	HOH2166
J	HOH2167
J	HOH2168
K	HIS353
K	LYS356
K	HEC1005
L	ARG141
L	MET148

site_id	IC6
Number of Residues	17
Details	BINDING SITE FOR RESIDUE HEM K1001

Chain	Residue
K	TYR115
K	ARG116
K	ALA118
K	PHE128
K	ILE131
K	ARG133
K	CYS147
K	CYS150
K	LYS151
K	CYS232
K	HIS233
K	TYR236
K	HIS298
K	ASN429
K	HEC1003
K	HOH2021
K	HOH2098

site_id	IC7
Number of Residues	22
Details	BINDING SITE FOR RESIDUE HEM K1002

Chain	Residue
K	TYR39
K	PHE57
K	GLN60
K	TYR64
K	GLY186
K	CYS187
K	CYS190
K	HIS191
K	MET196
K	LEU198
K	ARG221
K	ARG225
K	VAL228
K	MET321
K	TYR323
K	ILE332
K	SER333
K	HIS335
K	TRP337
K	HEC1003
K	HOH2099
L	ALA157

site_id	IC8
Number of Residues	27
Details	BINDING SITE FOR RESIDUE HEM K1003

Chain	Residue
K	GLY78
K	SER79
K	ALA118
K	ARG119
K	GLY120
K	HIS121
K	TYR123
K	ALA124
K	ASP127
K	CYS150
K	LYS151
K	ILE185
K	THR189
K	VAL228
K	CYS229
K	CYS232
K	HIS233
K	HIS320
K	MET321
K	TRP337
K	THR338
K	HEC1001
K	HEC1002
K	HEC1004
K	CA1007
K	HOH2100
K	HOH2101

site_id	IC9
Number of Residues	24
Details	BINDING SITE FOR RESIDUE HEM K1004

Chain	Residue
K	THR74
K	LYS77
K	GLY78
K	GLU117
K	CYS229
K	HIS233
K	TRP304
K	HIS309
K	VAL314
K	THR315
K	CYS316
K	CYS319
K	HIS320
K	SER339
K	MET341
K	GLN369
K	ASN429
K	PHE433
K	HIS434
K	HEC1003
K	HEC1005
K	CA1007
K	HOH2068
K	HOH2102

site_id	JC1
Number of Residues	23
Details	BINDING SITE FOR RESIDUE HEM K1005

Chain	Residue
J	HIS353
J	LYS356
J	HEC1005
J	HOH2112
K	HIS309
K	VAL314
K	ASP318
K	CYS319
K	PRO340
K	ALA348
K	CYS349
K	CYS352
K	HIS353
K	ARG364
K	VAL365
K	PRO436
K	HEC1004
K	HOH2103
K	HOH2104
K	HOH2105
K	HOH2106
L	MET148
L	LYS149

site_id	JC2
Number of Residues	20
Details	BINDING SITE FOR RESIDUE HEM L1002

Chain	Residue
L	ARG40
L	CYS43
L	MET49
L	VAL52
L	HIS56
L	HIS61
L	CYS66
L	CYS69
L	HIS70
L	ILE102
L	ALA104
L	LYS109
L	VAL112
L	THR137
L	VAL143
L	GLN144
L	HIS145
L	HEC1101
L	HOH2012
L	HOH2040

site_id	JC3
Number of Residues	22
Details	BINDING SITE FOR RESIDUE HEM L1003

Chain	Residue
G	LYS329
I	CYS119
I	HIS120
I	MET122
I	THR123
I	ACT1006
L	GLY60
L	HIS61
L	ILE64
L	ASP68
L	CYS69
L	VAL112
L	ASN115
L	CYS116
L	CYS119
L	HIS120
L	HIS140
L	VAL143
L	HEC1004
L	HOH2041
L	HOH2042
L	HOH2043

site_id	JC4
Number of Residues	19
Details	BINDING SITE FOR RESIDUE HEM L1004

Chain	Residue
G	ARG325
G	LYS329
I	HEC1004
I	ACT1006
J	TYR323
J	THR324
J	ARG325
J	LYS331
J	ARG347
J	GLN351
L	CYS116
L	HIS120
L	ASN124
L	SER129
L	LYS133
L	CYS136
L	CYS139
L	HIS140
L	HEC1003

site_id	JC5
Number of Residues	9
Details	BINDING SITE FOR RESIDUE LMT L1005

Chain	Residue
I	LYS35
J	GLY26
J	SER28
J	ASP29
J	VAL30
L	HIS73
L	ASN74
L	LEU75
L	LEU76

site_id	JC6
Number of Residues	12
Details	BINDING SITE FOR RESIDUE HEM L1101

Chain	Residue
L	THR37
L	CYS43
L	CYS46
L	MET49
L	ASN67
L	HIS70
L	ASP89
L	PRO98
L	ALA104
L	GLY105
L	THR108
L	HEC1002

site_id	JC7
Number of Residues	19
Details	BINDING SITE FOR RESIDUE HEM M1001

Chain	Residue
M	TYR115
M	ARG116
M	ALA118
M	PHE128
M	ILE131
M	ARG133
M	CYS147
M	CYS150
M	LYS151
M	CYS232
M	HIS233
M	TYR236
M	HIS298
M	ASN429
M	HEC1003
M	HOH2044
M	HOH2045
M	HOH2193
M	HOH2194

site_id	JC8
Number of Residues	22
Details	BINDING SITE FOR RESIDUE HEM M1002

Chain	Residue
M	TYR39
M	PHE57
M	GLN60
M	TYR61
M	TYR64
M	GLY186
M	CYS187
M	CYS190
M	HIS191
M	MET196
M	LEU198
M	ARG221
M	ARG225
M	MET321
M	SER333
M	HIS335
M	TRP337
M	HEC1003
M	HOH2116
M	HOH2195
M	HOH2196
O	VAL127

site_id	JC9
Number of Residues	25
Details	BINDING SITE FOR RESIDUE HEM M1003

Chain	Residue
M	GLY78
M	SER79
M	ALA118
M	ARG119
M	GLY120
M	HIS121
M	TYR123
M	ALA124
M	ASP127
M	CYS150
M	ILE185
M	THR189
M	VAL228
M	CYS229
M	CYS232
M	HIS233
M	HIS320
M	TRP337
M	THR338
M	HEC1001
M	HEC1002
M	HEC1004
M	CA1007
M	HOH2046
M	HOH2197

site_id	KC1
Number of Residues	24
Details	BINDING SITE FOR RESIDUE HEM M1004

Chain	Residue
M	THR74
M	LYS77
M	GLY78
M	GLU117
M	HIS233
M	GLU300
M	TYR301
M	TRP304
M	HIS309
M	THR315
M	CYS316
M	CYS319
M	HIS320
M	SER339
M	MET341
M	GLN369
M	ASN429
M	PHE433
M	HIS434
M	HEC1003
M	CA1007
M	HOH2198
M	HOH2199
M	HOH2200

site_id	KC2
Number of Residues	23
Details	BINDING SITE FOR RESIDUE HEM M1005

Chain	Residue
M	THR308
M	HIS309
M	ALA312
M	VAL314
M	ASP318
M	CYS319
M	PRO340
M	ALA348
M	CYS349
M	CYS352
M	HIS353
M	ARG364
M	VAL365
M	HOH2137
M	HOH2201
M	HOH2202
M	HOH2203
N	HIS353
N	LYS356
N	HEC1005
N	HOH2139
O	ARG141
O	MET148

site_id	KC3
Number of Residues	20
Details	BINDING SITE FOR RESIDUE HEM N1001

Chain	Residue
N	TYR115
N	ARG116
N	ALA118
N	PHE128
N	ILE131
N	ARG133
N	CYS147
N	CYS150
N	LYS151
N	CYS232
N	HIS233
N	TYR236
N	HIS298
N	ASN429
N	HEC1003
N	HOH2042
N	HOH2060
N	HOH2198
N	HOH2199
N	HOH2200

site_id	KC4
Number of Residues	21
Details	BINDING SITE FOR RESIDUE HEM N1002

Chain	Residue
N	TYR39
N	PHE57
N	GLN60
N	TYR64
N	GLY186
N	CYS187
N	CYS190
N	HIS191
N	MET196
N	LEU198
N	ARG221
N	ARG225
N	MET321
N	TYR323
N	ILE332
N	SER333
N	HIS335
N	TRP337
N	HEC1003
N	HOH2125
O	ALA157

site_id	KC5
Number of Residues	27
Details	BINDING SITE FOR RESIDUE HEM N1003

Chain	Residue
N	GLY78
N	SER79
N	ALA118
N	ARG119
N	HIS121
N	TYR123
N	ALA124
N	ASP127
N	CYS150
N	LYS151
N	ILE185
N	THR189
N	VAL228
N	CYS229
N	CYS232
N	HIS233
N	HIS320
N	TRP337
N	THR338
N	HEC1001
N	HEC1002
N	HEC1004
N	CA1007
N	HOH2020
N	HOH2044
N	HOH2072
N	HOH2201

site_id	KC6
Number of Residues	25
Details	BINDING SITE FOR RESIDUE HEM N1004

Chain	Residue
N	THR74
N	LYS77
N	GLY78
N	GLU117
N	HIS233
N	TYR301
N	TRP304
N	HIS309
N	VAL314
N	THR315
N	CYS316
N	CYS319
N	HIS320
N	SER339
N	PRO340
N	MET341
N	GLN369
N	ASN429
N	PHE433
N	HIS434
N	HEC1003
N	HEC1005
N	CA1007
N	HOH2201
N	HOH2202

site_id	KC7
Number of Residues	22
Details	BINDING SITE FOR RESIDUE HEM N1005

Chain	Residue
M	THR308
M	HIS353
M	LYS356
M	HEC1005
N	HIS309
N	VAL314
N	ASP318
N	CYS319
N	PRO340
N	ALA348
N	CYS349
N	CYS352
N	HIS353
N	ARG364
N	VAL365
N	HEC1004
N	HOH2203
N	HOH2204
N	HOH2205
N	HOH2206
O	MET148
O	LYS149

site_id	KC8
Number of Residues	17
Details	BINDING SITE FOR RESIDUE HEM O1001

Chain	Residue
O	THR37
O	CYS43
O	CYS46
O	ILE48
O	MET49
O	ASN67
O	HIS70
O	ASP89
O	VAL90
O	MET92
O	ASN93
O	PRO98
O	LEU103
O	ALA104
O	GLY105
O	THR108
O	HEC1002

site_id	KC9
Number of Residues	20
Details	BINDING SITE FOR RESIDUE HEM O1002

Chain	Residue
O	CYS43
O	MET49
O	VAL52
O	HIS56
O	HIS61
O	SER65
O	CYS66
O	CYS69
O	HIS70
O	ALA104
O	LYS109
O	VAL112
O	THR137
O	VAL143
O	GLN144
O	HIS145
O	HEC1001
O	HOH2022
O	HOH2040
O	HOH2049

site_id	LC1
Number of Residues	18
Details	BINDING SITE FOR RESIDUE HEM O1003

Chain	Residue
O	GLY60
O	HIS61
O	ASP68
O	VAL112
O	ASN115
O	CYS116
O	CYS119
O	HIS120
O	HIS140
O	HEC1004
O	ACT1006
O	HOH2011
O	HOH2050
P	LYS329
R	CYS119
R	HIS120
R	MET122
R	THR123

site_id	LC2
Number of Residues	18
Details	BINDING SITE FOR RESIDUE HEM O1004

Chain	Residue
M	ASP318
M	TYR323
M	THR324
M	ARG325
M	LYS331
M	GLN351
O	CYS116
O	HIS120
O	ASN124
O	SER129
O	LYS133
O	CYS136
O	CYS139
O	HIS140
O	HEC1003
P	ARG325
P	LYS329
R	HEC1004

site_id	LC3
Number of Residues	9
Details	BINDING SITE FOR RESIDUE LMT O1005

Chain	Residue
M	GLY26
M	SER28
M	ASP29
M	VAL30
O	HIS73
O	ASN74
O	LEU75
O	ALA118
R	LYS35

site_id	LC4
Number of Residues	20
Details	BINDING SITE FOR RESIDUE HEM P1001

Chain	Residue
P	TYR115
P	ARG116
P	ALA118
P	PHE128
P	ILE131
P	ARG133
P	CYS147
P	CYS150
P	LYS151
P	CYS232
P	HIS233
P	TYR236
P	HIS298
P	ASN429
P	HEC1003
P	HOH2044
P	HOH2045
P	HOH2101
P	HOH2166
P	HOH2167

site_id	LC5
Number of Residues	23
Details	BINDING SITE FOR RESIDUE HEM P1002

Chain	Residue
P	TYR39
P	PHE57
P	GLN60
P	TYR61
P	TYR64
P	GLY186
P	CYS187
P	CYS190
P	HIS191
P	MET196
P	LEU198
P	ARG221
P	ARG225
P	MET321
P	ILE332
P	SER333
P	HIS335
P	TRP337
P	HEC1003
P	HOH2110
P	HOH2168
R	VAL127
R	HOH2030

site_id	LC6
Number of Residues	24
Details	BINDING SITE FOR RESIDUE HEM P1003

Chain	Residue
P	GLY78
P	SER79
P	ALA118
P	ARG119
P	GLY120
P	HIS121
P	TYR123
P	ALA124
P	ASP127
P	CYS150
P	ILE185
P	VAL228
P	CYS229
P	CYS232
P	HIS233
P	HIS320
P	MET321
P	TRP337
P	THR338
P	HEC1001
P	HEC1002
P	HEC1004
P	CA1007
P	HOH2027

site_id	LC7
Number of Residues	24
Details	BINDING SITE FOR RESIDUE HEM P1004

Chain	Residue
P	THR74
P	LYS77
P	GLY78
P	GLU117
P	HIS233
P	TYR301
P	TRP304
P	HIS309
P	VAL314
P	THR315
P	CYS316
P	CYS319
P	HIS320
P	SER339
P	MET341
P	GLN369
P	ASN429
P	PHE433
P	HIS434
P	HEC1003
P	HEC1005
P	CA1007
P	HOH2130
P	HOH2169

site_id	LC8
Number of Residues	22
Details	BINDING SITE FOR RESIDUE HEM P1005

Chain	Residue
P	THR308
P	HIS309
P	ALA312
P	CYS319
P	ALA348
P	CYS349
P	CYS352
P	HIS353
P	ARG364
P	VAL365
P	PHE433
P	HEC1004
P	HOH2170
P	HOH2171
P	HOH2172
P	HOH2173
Q	HIS353
Q	LYS356
Q	HEC1005
Q	HOH2081
R	ARG141
R	MET148

site_id	LC9
Number of Residues	20
Details	BINDING SITE FOR RESIDUE HEM Q1001

Chain	Residue
Q	TYR115
Q	ARG116
Q	ALA118
Q	ASP127
Q	PHE128
Q	ARG133
Q	CYS147
Q	CYS150
Q	LYS151
Q	CYS232
Q	HIS233
Q	TYR236
Q	HIS298
Q	ASN429
Q	HEC1003
Q	HOH2029
Q	HOH2121
Q	HOH2122
Q	HOH2123
Q	HOH2124

site_id	MC1
Number of Residues	22
Details	BINDING SITE FOR RESIDUE HEM Q1002

Chain	Residue
Q	TYR39
Q	PHE57
Q	GLN60
Q	TYR61
Q	TYR64
Q	GLY186
Q	CYS187
Q	CYS190
Q	HIS191
Q	MET196
Q	LEU198
Q	ARG221
Q	ARG225
Q	MET321
Q	TYR323
Q	ILE332
Q	SER333
Q	HIS335
Q	TRP337
Q	HEC1003
Q	HOH2069
R	ALA157

site_id	MC2
Number of Residues	27
Details	BINDING SITE FOR RESIDUE HEM Q1003

Chain	Residue
Q	GLY78
Q	SER79
Q	ALA118
Q	ARG119
Q	GLY120
Q	HIS121
Q	TYR123
Q	ALA124
Q	ASP127
Q	CYS150
Q	LYS151
Q	ILE185
Q	THR189
Q	VAL228
Q	CYS229
Q	CYS232
Q	HIS233
Q	HIS320
Q	MET321
Q	TRP337
Q	THR338
Q	HEC1001
Q	HEC1002
Q	HEC1004
Q	CA1007
Q	HOH2006
Q	HOH2125

site_id	MC3
Number of Residues	26
Details	BINDING SITE FOR RESIDUE HEM Q1004

Chain	Residue
Q	THR74
Q	LYS77
Q	GLU117
Q	ALA118
Q	HIS233
Q	GLU300
Q	TRP304
Q	HIS309
Q	VAL314
Q	THR315
Q	CYS316
Q	CYS319
Q	HIS320
Q	SER339
Q	PRO340
Q	MET341
Q	GLN369
Q	ASN429
Q	SER430
Q	PHE433
Q	HIS434
Q	HEC1003
Q	HEC1005
Q	CA1007
Q	HOH2087
Q	HOH2127

site_id	MC4
Number of Residues	26
Details	BINDING SITE FOR RESIDUE HEM Q1005

Chain	Residue
P	HIS353
P	LYS356
P	HEC1005
Q	THR308
Q	HIS309
Q	VAL314
Q	ASP318
Q	CYS319
Q	PRO340
Q	ALA348
Q	CYS349
Q	CYS352
Q	HIS353
Q	ARG364
Q	VAL365
Q	PHE433
Q	PRO436
Q	HEC1004
Q	HOH2128
Q	HOH2129
Q	HOH2130
Q	HOH2131
Q	HOH2132
R	ARG141
R	MET148
R	LYS149

site_id	MC5
Number of Residues	15
Details	BINDING SITE FOR RESIDUE HEM R1001

Chain	Residue
R	THR37
R	CYS43
R	CYS46
R	ILE48
R	MET49
R	ASN67
R	HIS70
R	ASP89
R	MET92
R	ILE102
R	ALA104
R	GLY105
R	THR108
R	HEC1002
R	HOH2041

site_id	MC6
Number of Residues	17
Details	BINDING SITE FOR RESIDUE HEM R1002

Chain	Residue
R	MET49
R	VAL52
R	GLY53
R	HIS56
R	HIS61
R	SER65
R	CYS66
R	CYS69
R	HIS70
R	LYS109
R	VAL112
R	THR137
R	VAL143
R	GLN144
R	HIS145
R	HEC1001
R	HOH2042

site_id	MC7
Number of Residues	20
Details	BINDING SITE FOR RESIDUE HEM R1003

Chain	Residue
M	LYS329
O	CYS119
O	HIS120
O	MET122
O	THR123
O	ACT1006
R	GLY60
R	HIS61
R	ILE64
R	ASP68
R	VAL112
R	ASN115
R	CYS116
R	CYS119
R	HIS120
R	HIS140
R	VAL143
R	HOH2011
R	HOH2043
R	HOH2044

site_id	MC8
Number of Residues	16
Details	BINDING SITE FOR RESIDUE HEM R1004

Chain	Residue
M	ARG325
O	HEC1004
O	ACT1006
P	TYR323
P	ARG325
P	LYS331
P	ARG347
P	GLN351
R	CYS116
R	HIS120
R	ASN124
R	SER129
R	LYS133
R	CYS136
R	CYS139
R	HIS140

site_id	MC9
Number of Residues	9
Details	BINDING SITE FOR RESIDUE LMT R1005

Chain	Residue
O	LYS35
P	GLY26
P	SER28
P	ASP29
P	VAL30
R	HIS73
R	ASN74
R	LEU75
R	ALA118

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	336
Details	Region: {"description":"Interaction with NrfH","evidences":[{"source":"PubMed","id":"17139260","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2J7A","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI2
Number of Residues	84
Details	Binding site: {"evidences":[{"source":"PubMed","id":"17139260","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18597779","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2J7A","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2VR0","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI3
Number of Residues	138
Details	Binding site: {"description":"axial binding residue","evidences":[{"source":"PubMed","id":"17139260","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18597779","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2J7A","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2VR0","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI4
Number of Residues	72
Details	Binding site: {"description":"covalent","evidences":[{"source":"PubMed","id":"17139260","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2J7A","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI5
Number of Residues	84
Details	Binding site: {"description":"covalent","evidences":[{"source":"PubMed","id":"17139260","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18597779","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2J7A","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2VR0","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI6
Number of Residues	12
Details	Binding site: {"description":"covalent","evidences":[{"source":"PubMed","id":"18597779","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2VR0","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI7
Number of Residues	12
Details	Site: {"description":"Interaction with NrfH","evidences":[{"source":"PubMed","id":"17139260","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2J7A","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI8
Number of Residues	108
Details	Transmembrane: {"description":"Helical; Signal-anchor for type II membrane protein","evidences":[{"evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"17139260","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18597779","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

site_id	SWS_FT_FI9
Number of Residues	216
Details	Region: {"description":"Interaction with NrfA","evidences":[{"source":"PubMed","id":"17139260","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2J7A","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI10
Number of Residues	12
Details	Binding site: {"description":"axial binding residue","evidences":[{"source":"PubMed","id":"17139260","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2J7A","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI11
Number of Residues	12
Details	Binding site: {"evidences":[{"source":"PubMed","id":"18597779","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2VR0","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI12
Number of Residues	18
Details	Site: {"description":"Interaction with NrfA","evidences":[{"source":"PubMed","id":"17139260","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2J7A","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)