2J6P

STRUCTURE OF AS-SB REDUCTASE FROM LEISHMANIA MAJOR

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004725	molecular_function	protein tyrosine phosphatase activity
A	0005634	cellular_component	nucleus
A	0005737	cellular_component	cytoplasm
B	0004725	molecular_function	protein tyrosine phosphatase activity
B	0005634	cellular_component	nucleus
B	0005737	cellular_component	cytoplasm
C	0004725	molecular_function	protein tyrosine phosphatase activity
C	0005634	cellular_component	nucleus
C	0005737	cellular_component	cytoplasm
D	0004725	molecular_function	protein tyrosine phosphatase activity
D	0005634	cellular_component	nucleus
D	0005737	cellular_component	cytoplasm
E	0004725	molecular_function	protein tyrosine phosphatase activity
E	0005634	cellular_component	nucleus
E	0005737	cellular_component	cytoplasm
F	0004725	molecular_function	protein tyrosine phosphatase activity
F	0005634	cellular_component	nucleus
F	0005737	cellular_component	cytoplasm

Functional Information from PDB Data

site_id	AC1
Number of Residues	12
Details	binding site for residue EPE A 201

Chain	Residue
A	CYS75
B	EPE201
B	SO4205
B	HOH375
A	ALA76
A	GLN77
A	SER78
A	LEU79
A	VAL80
A	ARG81
A	SO4203
B	VAL80

---

site_id	AC2
Number of Residues	4
Details	binding site for residue GOL A 202

Chain	Residue
A	TYR6
A	ARG107
A	HOH303
C	HIS115

---

site_id	AC3
Number of Residues	9
Details	binding site for residue SO4 A 203

Chain	Residue
A	CYS75
A	ALA76
A	GLN77
A	SER78
A	LEU79
A	VAL80
A	ARG81
A	EPE201
B	EPE201

---

site_id	AC4
Number of Residues	6
Details	binding site for residue SO4 A 204

Chain	Residue
A	LYS84
A	ARG88
E	CYS51
E	THR52
E	GLU53
E	ARG88

---

site_id	AC5
Number of Residues	12
Details	binding site for residue EPE B 201

Chain	Residue
A	VAL80
A	ARG81
A	EPE201
A	SO4203
A	HOH377
B	CYS75
B	ALA76
B	GLN77
B	LEU79
B	VAL80
B	ARG81
B	SO4205

---

site_id	AC6
Number of Residues	4
Details	binding site for residue GOL B 202

Chain	Residue
A	SER33
B	HIS115
B	HOH314
B	HOH370

---

site_id	AC7
Number of Residues	4
Details	binding site for residue GOL B 203

Chain	Residue
B	TYR6
B	LYS8
B	ARG107
D	HIS115

---

site_id	AC8
Number of Residues	4
Details	binding site for residue SO4 B 204

Chain	Residue
B	THR52
B	GLU53
C	LYS84
C	ARG88

---

site_id	AC9
Number of Residues	9
Details	binding site for residue SO4 B 205

Chain	Residue
A	EPE201
B	CYS75
B	ALA76
B	GLN77
B	SER78
B	LEU79
B	VAL80
B	ARG81
B	EPE201

---

site_id	AD1
Number of Residues	11
Details	binding site for residue EPE C 201

Chain	Residue
C	CYS75
C	ALA76
C	GLN77
C	SER78
C	LEU79
C	VAL80
C	ARG81
C	HOH332
C	HOH339
E	ARG81
E	SO4202

---

site_id	AD2
Number of Residues	4
Details	binding site for residue GOL C 202

Chain	Residue
A	HIS115
C	LYS8
C	ARG107
C	HOH365

---

site_id	AD3
Number of Residues	10
Details	binding site for residue EPE D 201

Chain	Residue
D	CYS75
D	ALA76
D	GLN77
D	SER78
D	LEU79
D	VAL80
D	ARG81
D	HOH310
F	ARG81
F	SO4201

---

site_id	AD4
Number of Residues	2
Details	binding site for residue GOL D 202

Chain	Residue
D	HIS115
D	HOH320

---

site_id	AD5
Number of Residues	6
Details	binding site for residue SO4 D 203

Chain	Residue
A	THR52
A	GLU53
D	LYS84
D	ARG88
D	HOH321
D	HOH328

---

site_id	AD6
Number of Residues	6
Details	binding site for residue SO4 D 204

Chain	Residue
D	ARG107
D	HOH301
D	HOH338
D	HOH340
B	HIS115
D	LYS8

---

site_id	AD7
Number of Residues	5
Details	binding site for residue GOL E 201

Chain	Residue
A	ARG107
C	HIS115
C	HOH320
E	SER33
E	HOH304

---

site_id	AD8
Number of Residues	8
Details	binding site for residue SO4 E 202

Chain	Residue
C	EPE201
E	CYS75
E	ALA76
E	GLN77
E	SER78
E	LEU79
E	VAL80
E	ARG81

---

site_id	AD9
Number of Residues	10
Details	binding site for residue SO4 F 201

Chain	Residue
D	EPE201
F	CYS75
F	ALA76
F	GLN77
F	SER78
F	LEU79
F	VAL80
F	ARG81
F	HOH303
F	HOH314

---

site_id	AE1
Number of Residues	6
Details	binding site for residue SO4 F 202

Chain	Residue
B	LYS84
B	ARG88
F	CYS51
F	THR52
F	GLU53
F	ARG88

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