2J37

MODEL OF MAMMALIAN SRP BOUND TO 80S RNCS

Functional Information from GO Data

Chain	GOid	namespace	contents
4	0003735	molecular_function	structural constituent of ribosome
4	0005840	cellular_component	ribosome
4	0006412	biological_process	translation
4	0019843	molecular_function	rRNA binding
4	1990904	cellular_component	ribonucleoprotein complex
5	0000463	biological_process	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
5	0003729	molecular_function	mRNA binding
5	0003735	molecular_function	structural constituent of ribosome
5	0005840	cellular_component	ribosome
5	0006412	biological_process	translation
5	0022625	cellular_component	cytosolic large ribosomal subunit
5	1990904	cellular_component	ribonucleoprotein complex
6	0003735	molecular_function	structural constituent of ribosome
6	0005840	cellular_component	ribosome
6	0006412	biological_process	translation
6	1990904	cellular_component	ribonucleoprotein complex
B	0006614	biological_process	SRP-dependent cotranslational protein targeting to membrane
B	0008312	molecular_function	7S RNA binding
B	0048500	cellular_component	signal recognition particle
W	0003723	molecular_function	RNA binding
W	0003924	molecular_function	GTPase activity
W	0005525	molecular_function	GTP binding
W	0005634	cellular_component	nucleus
W	0005737	cellular_component	cytoplasm
W	0005783	cellular_component	endoplasmic reticulum
W	0005786	cellular_component	signal recognition particle, endoplasmic reticulum targeting
W	0005829	cellular_component	cytosol
W	0006614	biological_process	SRP-dependent cotranslational protein targeting to membrane
W	0006616	biological_process	SRP-dependent cotranslational protein targeting to membrane, translocation
W	0006617	biological_process	SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition
W	0008312	molecular_function	7S RNA binding
W	0016607	cellular_component	nuclear speck
W	0016787	molecular_function	hydrolase activity
W	0016887	molecular_function	ATP hydrolysis activity
W	0019003	molecular_function	GDP binding
W	0030593	biological_process	neutrophil chemotaxis
W	0030851	biological_process	granulocyte differentiation
W	0030942	molecular_function	endoplasmic reticulum signal peptide binding
W	0031017	biological_process	exocrine pancreas development
W	0043021	molecular_function	ribonucleoprotein complex binding
W	0045047	biological_process	protein targeting to ER
W	0048500	cellular_component	signal recognition particle

Functional Information from PROSITE/UniProt

site_id	PS00050
Number of Residues	16
Details	RIBOSOMAL_L23 Ribosomal protein L23 signature. KKAYVKLTpdydaldV

Chain	Residue	Details
4	LYS130-VAL145

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site_id	PS00300
Number of Residues	14
Details	SRP54 SRP54-type proteins GTP-binding domain signature. PIiFIGTGEhIddF

Chain	Residue	Details
W	PRO269-PHE282

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	3
Details	BINDING: BINDING => ECO:0000250

Chain	Residue	Details
W	GLY108
W	ASP190
W	THR248

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