2J1L

Crystal Structure of Human Rho-related GTP-binding protein RhoD

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000139	cellular_component	Golgi membrane
A	0003924	molecular_function	GTPase activity
A	0003925	molecular_function	G protein activity
A	0005085	molecular_function	guanyl-nucleotide exchange factor activity
A	0005515	molecular_function	protein binding
A	0005525	molecular_function	GTP binding
A	0005741	cellular_component	mitochondrial outer membrane
A	0005769	cellular_component	early endosome
A	0005829	cellular_component	cytosol
A	0005886	cellular_component	plasma membrane
A	0007015	biological_process	actin filament organization
A	0007266	biological_process	Rho protein signal transduction
A	0010008	cellular_component	endosome membrane
A	0019901	molecular_function	protein kinase binding
A	0030032	biological_process	lamellipodium assembly
A	0030335	biological_process	positive regulation of cell migration
A	0032956	biological_process	regulation of actin cytoskeleton organization
A	0045785	biological_process	positive regulation of cell adhesion
A	0048041	biological_process	focal adhesion assembly
A	0051017	biological_process	actin filament bundle assembly
A	0051056	biological_process	regulation of small GTPase mediated signal transduction
A	0051893	biological_process	regulation of focal adhesion assembly

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG A1195

Chain	Residue
A	THR31
A	GDP1194
A	HOH2002
A	HOH2003
A	HOH2004

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site_id	AC2
Number of Residues	16
Details	BINDING SITE FOR RESIDUE GDP A1194

Chain	Residue
A	LYS30
A	THR31
A	SER32
A	LYS130
A	ASP132
A	LEU133
A	SER172
A	ALA173
A	ARG174
A	MG1195
A	HOH2001
A	HOH2002
A	ASP25
A	GLY27
A	CYS28
A	GLY29

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"AUG-2006","submissionDatabase":"PDB data bank","title":"Crystal Structure of Human Rho-Related GTP-Binding Protein Rhod.","authors":["Pike A.C.W.","Johansson C.","Gileadi C.","Niesen F.H.","Sobott F.","Schoch G.","Elkins J.","Smee C.","Gorrec F.","Watt S.","Bray J.","Turnbull A.P.","von Delft F.","Arrowsmith C.","Edwards A.","Weigelt J.","Sundstrom M.","Doyle D."]}},{"source":"PDB","id":"2J1L","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	8
Details	Binding site: {"evidences":[{"source":"PubMed","id":"34114565","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"7KDC","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"34114565","evidenceCode":"ECO:0000269"},{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"AUG-2006","submissionDatabase":"PDB data bank","title":"Crystal Structure of Human Rho-Related GTP-Binding Protein Rhod.","authors":["Pike A.C.W.","Johansson C.","Gileadi C.","Niesen F.H.","Sobott F.","Schoch G.","Elkins J.","Smee C.","Gorrec F.","Watt S.","Bray J.","Turnbull A.P.","von Delft F.","Arrowsmith C.","Edwards A.","Weigelt J.","Sundstrom M.","Doyle D."]}},{"source":"PDB","id":"2J1L","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7KDC","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI4
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"34114565","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7KDC","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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