Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

2J1L

Crystal Structure of Human Rho-related GTP-binding protein RhoD

Functional Information from GO Data
ChainGOidnamespacecontents
A0000139cellular_componentGolgi membrane
A0000166molecular_functionnucleotide binding
A0003924molecular_functionGTPase activity
A0005085molecular_functionguanyl-nucleotide exchange factor activity
A0005525molecular_functionGTP binding
A0005741cellular_componentmitochondrial outer membrane
A0005768cellular_componentendosome
A0005769cellular_componentearly endosome
A0005829cellular_componentcytosol
A0005886cellular_componentplasma membrane
A0007015biological_processactin filament organization
A0007165biological_processsignal transduction
A0007264biological_processsmall GTPase-mediated signal transduction
A0007266biological_processRho protein signal transduction
A0010008cellular_componentendosome membrane
A0016020cellular_componentmembrane
A0016477biological_processcell migration
A0019901molecular_functionprotein kinase binding
A0030032biological_processlamellipodium assembly
A0030335biological_processpositive regulation of cell migration
A0032956biological_processregulation of actin cytoskeleton organization
A0045785biological_processpositive regulation of cell adhesion
A0048041biological_processfocal adhesion assembly
A0051017biological_processactin filament bundle assembly
A0051056biological_processregulation of small GTPase mediated signal transduction
Functional Information from PDB Data
site_idAC1
Number of Residues5
DetailsBINDING SITE FOR RESIDUE MG A1195
ChainResidue
ATHR31
AGDP1194
AHOH2002
AHOH2003
AHOH2004

site_idAC2
Number of Residues16
DetailsBINDING SITE FOR RESIDUE GDP A1194
ChainResidue
ALYS30
ATHR31
ASER32
ALYS130
AASP132
ALEU133
ASER172
AALA173
AARG174
AMG1195
AHOH2001
AHOH2002
AASP25
AGLY27
ACYS28
AGLY29

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues3
DetailsBINDING: BINDING => ECO:0000250
ChainResidueDetails
AGLY24
AASP71
ACYS129

218853

PDB entries from 2024-04-24

PDB statisticsPDBj update infoContact PDBjnumon