Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004616 | molecular_function | phosphogluconate dehydrogenase (decarboxylating) activity |
| A | 0006098 | biological_process | pentose-phosphate shunt |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0019521 | biological_process | D-gluconate metabolic process |
| A | 0050661 | molecular_function | NADP binding |
| B | 0004616 | molecular_function | phosphogluconate dehydrogenase (decarboxylating) activity |
| B | 0006098 | biological_process | pentose-phosphate shunt |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0019521 | biological_process | D-gluconate metabolic process |
| B | 0050661 | molecular_function | NADP binding |
| C | 0004616 | molecular_function | phosphogluconate dehydrogenase (decarboxylating) activity |
| C | 0006098 | biological_process | pentose-phosphate shunt |
| C | 0016491 | molecular_function | oxidoreductase activity |
| C | 0019521 | biological_process | D-gluconate metabolic process |
| C | 0050661 | molecular_function | NADP binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE 5RP A1471 |
| Chain | Residue |
| A | ASN102 |
| A | NAP1470 |
| A | HOH2034 |
| A | HOH2069 |
| A | HOH2136 |
| B | ARG447 |
| B | PHE450 |
| B | HIS453 |
| A | LYS184 |
| A | HIS187 |
| A | ASN188 |
| A | GLU191 |
| A | TYR192 |
| A | LYS262 |
| A | THR264 |
| A | ARG289 |
| site_id | AC2 |
| Number of Residues | 23 |
| Details | BINDING SITE FOR RESIDUE NAP A1470 |
| Chain | Residue |
| A | GLY10 |
| A | MET11 |
| A | VAL13 |
| A | MET14 |
| A | ASN33 |
| A | ARG34 |
| A | THR35 |
| A | LYS38 |
| A | MET73 |
| A | VAL74 |
| A | GLN75 |
| A | ALA79 |
| A | GLY101 |
| A | ASN102 |
| A | VAL127 |
| A | GLY130 |
| A | LYS184 |
| A | 5RP1471 |
| A | HOH2034 |
| A | HOH2135 |
| A | HOH2136 |
| A | HOH2137 |
| B | GLY451 |
| site_id | AC3 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE A2P B1470 |
| Chain | Residue |
| B | GLY10 |
| B | MET11 |
| B | ALA12 |
| B | ASN33 |
| B | ARG34 |
| B | THR35 |
| B | LYS38 |
| B | VAL74 |
| B | GLN75 |
| B | ALA79 |
| B | HOH2134 |
| B | HOH2135 |
| B | HOH2136 |
| site_id | AC4 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE A2P C1470 |
| Chain | Residue |
| C | GLY10 |
| C | ASN33 |
| C | ARG34 |
| C | THR35 |
| C | LYS38 |
| C | VAL74 |
| C | GLN75 |
| C | ALA79 |
| C | THR83 |
| C | HOH2150 |
| C | HOH2151 |
| C | HOH2152 |
Functional Information from PROSITE/UniProt
| site_id | PS00461 |
| Number of Residues | 13 |
| Details | 6PGD 6-phosphogluconate dehydrogenase signature. IlDkaGNKGTGkW |
| Chain | Residue | Details |
| A | ILE255-TRP267 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 3 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"source":"PubMed","id":"17222187","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 3 |
| Details | Active site: {"description":"Proton donor","evidences":[{"source":"PubMed","id":"17222187","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 33 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"17222187","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 21 |
| Details | Binding site: {"description":"in other chain","evidences":[{"source":"PubMed","id":"17222187","evidenceCode":"ECO:0000269"}]} |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 2pgd |
| Chain | Residue | Details |
| A | GLY130 | |
| A | GLU191 | |
| A | LYS184 | |
| A | ASN188 | |
| site_id | CSA2 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 2pgd |
| Chain | Residue | Details |
| B | GLY130 | |
| B | GLU191 | |
| B | LYS184 | |
| B | ASN188 | |
| site_id | CSA3 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 2pgd |
| Chain | Residue | Details |
| C | GLY130 | |
| C | GLU191 | |
| C | LYS184 | |
| C | ASN188 | |
