Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003676 | molecular_function | nucleic acid binding |
| A | 0003723 | molecular_function | RNA binding |
| A | 0004518 | molecular_function | nuclease activity |
| A | 0004527 | molecular_function | exonuclease activity |
| A | 0004540 | molecular_function | RNA nuclease activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0006401 | biological_process | RNA catabolic process |
| A | 0006402 | biological_process | mRNA catabolic process |
| A | 0008408 | molecular_function | 3'-5' exonuclease activity |
| A | 0008859 | molecular_function | exoribonuclease II activity |
| A | 0016070 | biological_process | RNA metabolic process |
| A | 0016078 | biological_process | tRNA decay |
| A | 0016787 | molecular_function | hydrolase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG A1644 |
| Chain | Residue |
| A | ASP201 |
| A | ASP210 |
| A | HOH2011 |
| A | HOH2013 |
| B | A12 |
| B | A13 |
Functional Information from PROSITE/UniProt
| site_id | PS01175 |
| Number of Residues | 25 |
| Details | RIBONUCLEASE_II Ribonuclease II family signature. HFGLglea.YAtWTSPIRKYgDminH |
| Chain | Residue | Details |
| A | HIS484-HIS508 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 327 |
| Details | Domain: {"description":"RNB","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 82 |
| Details | Domain: {"description":"S1 motif"} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"N6-acetyllysine; by PatZ","evidences":[{"source":"PubMed","id":"26847092","evidenceCode":"ECO:0000269"}]} |
Catalytic Information from CSA
| site_id | MCSA1 |
| Number of Residues | 6 |
| Details | M-CSA 338 |
| Chain | Residue | Details |
| A | ASP201 | metal ligand |
| A | ASP207 | metal ligand |
| A | ASN209 | activator, electrostatic stabiliser, increase nucleophilicity |
| A | ASP210 | metal ligand |
| A | TYR313 | activator, hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
| A | ARG500 | activator, electrostatic stabiliser, hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
