2IUA
C. trachomatis LpxD
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005829 | cellular_component | cytosol |
| A | 0006629 | biological_process | lipid metabolic process |
| A | 0009245 | biological_process | lipid A biosynthetic process |
| A | 0016020 | cellular_component | membrane |
| A | 0016410 | molecular_function | N-acyltransferase activity |
| A | 0016740 | molecular_function | transferase activity |
| A | 0016746 | molecular_function | acyltransferase activity |
| A | 0016747 | molecular_function | acyltransferase activity, transferring groups other than amino-acyl groups |
| A | 0103118 | molecular_function | UDP-3-O-[(3R)-3-hydroxyacyl]-glucosamine N-acyltransferase activity |
| B | 0005829 | cellular_component | cytosol |
| B | 0006629 | biological_process | lipid metabolic process |
| B | 0009245 | biological_process | lipid A biosynthetic process |
| B | 0016020 | cellular_component | membrane |
| B | 0016410 | molecular_function | N-acyltransferase activity |
| B | 0016740 | molecular_function | transferase activity |
| B | 0016746 | molecular_function | acyltransferase activity |
| B | 0016747 | molecular_function | acyltransferase activity, transferring groups other than amino-acyl groups |
| B | 0103118 | molecular_function | UDP-3-O-[(3R)-3-hydroxyacyl]-glucosamine N-acyltransferase activity |
| C | 0005829 | cellular_component | cytosol |
| C | 0006629 | biological_process | lipid metabolic process |
| C | 0009245 | biological_process | lipid A biosynthetic process |
| C | 0016020 | cellular_component | membrane |
| C | 0016410 | molecular_function | N-acyltransferase activity |
| C | 0016740 | molecular_function | transferase activity |
| C | 0016746 | molecular_function | acyltransferase activity |
| C | 0016747 | molecular_function | acyltransferase activity, transferring groups other than amino-acyl groups |
| C | 0103118 | molecular_function | UDP-3-O-[(3R)-3-hydroxyacyl]-glucosamine N-acyltransferase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A1348 |
| Chain | Residue |
| A | SER64 |
| A | ARG65 |
| A | THR66 |
| A | THR81 |
| A | SER82 |
| site_id | AC2 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE SO4 A1349 |
| Chain | Residue |
| A | ARG176 |
| site_id | AC3 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 A1350 |
| Chain | Residue |
| A | LYS16 |
| B | HIS272 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 B1346 |
| Chain | Residue |
| A | ARG72 |
| B | SER64 |
| B | ARG65 |
| B | THR66 |
| B | THR81 |
| B | HOH2012 |
| A | GLN20 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 B1347 |
| Chain | Residue |
| B | ILE285 |
| B | LYS301 |
| B | SER302 |
| site_id | AC6 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 B1348 |
| Chain | Residue |
| B | LYS175 |
| B | ARG176 |
| site_id | AC7 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE SO4 C1349 |
| Chain | Residue |
| C | ARG176 |
| site_id | AC8 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 C1350 |
| Chain | Residue |
| C | ARG65 |
| C | SER82 |
| site_id | AC9 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE MES A1347 |
| Chain | Residue |
| A | HIS290 |
| B | PHE14 |
| site_id | BC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PLM A1351 |
| Chain | Residue |
| A | ALA264 |
| A | THR282 |
| A | VAL299 |
| B | MET294 |
| B | ALA295 |
| site_id | BC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE PLM A1352 |
| Chain | Residue |
| A | GLN278 |
| A | ALA295 |
| C | GLY280 |
| C | ILE281 |
| C | THR282 |
| C | VAL299 |
| C | THR300 |
| site_id | BC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE PLM B1349 |
| Chain | Residue |
| B | GLY280 |
| B | ILE281 |
| B | ALA312 |
| C | ALA295 |
| C | GLY311 |
| C | ALA312 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 3 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"source":"PubMed","id":"17360522","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 6 |
| Details | Binding site: {} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 15 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"17360522","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 6 |
| Details | Site: {"description":"Participates in a stacking interaction with the uracil ring of UDP-GlcNAc"} |
| Chain | Residue | Details |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1lxa |
| Chain | Residue | Details |
| A | HIS247 |
| site_id | CSA2 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1lxa |
| Chain | Residue | Details |
| B | HIS247 |
| site_id | CSA3 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1lxa |
| Chain | Residue | Details |
| C | HIS247 |
