2IQ1

Crystal structure of human PPM1K

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004722	molecular_function	protein serine/threonine phosphatase activity
A	0006470	biological_process	protein dephosphorylation
A	0043169	molecular_function	cation binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG A 1

Chain	Residue
A	ASP127
A	GLY128
A	ASP337
A	HOH470
A	HOH472
A	HOH473

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Functional Information from PROSITE/UniProt

site_id	PS01032
Number of Residues	9
Details	PPM_1 PPM-type phosphatase domain signature. YFAVYDGHG

Chain	Residue	Details
A	TYR122-GLY130

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	3
Details	BINDING: BINDING => ECO:0000305|PubMed:22291014, ECO:0007744|PDB:4DA1

Chain	Residue	Details
A	ASP127
A	ASP298
A	ASP337

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site_id	SWS_FT_FI2
Number of Residues	1
Details	BINDING: BINDING => ECO:0000305|PubMed:22291014, ECO:0007744|PDB:2IQ1

Chain	Residue	Details
A	GLY128

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site_id	SWS_FT_FI3
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:Q8BXN7

Chain	Residue	Details
A	SER248

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