2IP4
Crystal Structure of Glycinamide Ribonucleotide Synthetase from Thermus thermophilus HB8
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0004637 | molecular_function | phosphoribosylamine-glycine ligase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0006164 | biological_process | purine nucleotide biosynthetic process |
| A | 0006189 | biological_process | 'de novo' IMP biosynthetic process |
| A | 0009113 | biological_process | purine nucleobase biosynthetic process |
| A | 0016874 | molecular_function | ligase activity |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0004637 | molecular_function | phosphoribosylamine-glycine ligase activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0006164 | biological_process | purine nucleotide biosynthetic process |
| B | 0006189 | biological_process | 'de novo' IMP biosynthetic process |
| B | 0009113 | biological_process | purine nucleobase biosynthetic process |
| B | 0016874 | molecular_function | ligase activity |
| B | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 A 418 |
| Chain | Residue |
| A | ARG11 |
| A | GLU70 |
| A | ARG281 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 A 419 |
| Chain | Residue |
| A | TYR332 |
| A | GLY370 |
| A | ARG371 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 B 418 |
| Chain | Residue |
| B | TYR332 |
| B | ARG371 |
| B | HOH427 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 B 419 |
| Chain | Residue |
| B | ARG11 |
| B | PRO69 |
| B | GLU70 |
| B | ARG281 |
| B | HOH432 |
Functional Information from PROSITE/UniProt
| site_id | PS00184 |
| Number of Residues | 8 |
| Details | GARS Phosphoribosylglycinamide synthetase signature. RFGDPEaQ |
| Chain | Residue | Details |
| A | ARG281-GLN288 |
