2IL1
Crystal structure of a predicted human GTPase in complex with GDP
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG A 402 |
| Chain | Residue |
| A | THR152 |
| A | GDP401 |
| A | HOH1013 |
| A | HOH1014 |
| A | HOH1015 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA A 501 |
| Chain | Residue |
| A | HOH1001 |
| A | HOH1001 |
| A | ASP290 |
| A | ASP290 |
| A | GLU291 |
| A | GLU291 |
| site_id | AC3 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE GDP A 401 |
| Chain | Residue |
| A | ARG147 |
| A | GLY148 |
| A | VAL149 |
| A | GLY150 |
| A | LYS151 |
| A | THR152 |
| A | SER153 |
| A | ASN251 |
| A | LYS252 |
| A | ASP254 |
| A | CYS255 |
| A | SER282 |
| A | ALA283 |
| A | LYS284 |
| A | MG402 |
| A | HOH1014 |
| A | UNX1404 |
| site_id | AC4 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE UNX A 1401 |
| Chain | Residue |
| A | CYS279 |
| A | ASN288 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE UNX A 1402 |
| Chain | Residue |
| A | ARG199 |
| A | PHE200 |
| A | SER202 |
| A | ILE203 |
| A | GLN272 |
| site_id | AC6 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE UNX A 1403 |
| Chain | Residue |
| A | ASP254 |
| A | ASP285 |
| site_id | AC7 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE UNX A 1404 |
| Chain | Residue |
| A | CYS255 |
| A | GDP401 |
| site_id | AC8 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE UNX A 1405 |
| Chain | Residue |
| A | ALA195 |
| A | LYS234 |
| A | ASP237 |
| site_id | AC9 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE UNX A 1406 |
| Chain | Residue |
| A | ASP254 |
| A | GLU256 |
| A | THR257 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 17 |
| Details | Motif: {"description":"Switch 2","evidences":[{"source":"UniProtKB","id":"P62820","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 14 |
| Details | Binding site: {"evidences":[{"source":"UniProtKB","id":"P61026","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 3 |
| Details | Binding site: {"evidences":[{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"FEB-2009","submissionDatabase":"PDB data bank","title":"Crystal structure of a predicted human GTPase in complex with GDP.","authoringGroup":["Structural genomics consortium (SGC)"]}},{"source":"PDB","id":"2IL1","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Phosphothreonine; by LRRK2","evidences":[{"source":"PubMed","id":"29125462","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 11 |
| Details | Binding site: {} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"Q8CG50","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1ksj |
| Chain | Residue | Details |
| A | GLN197 |
