2IJX
Crystal structure of PCNA3 monomer from Sulfolobus solfataricus.
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003677 | molecular_function | DNA binding |
| A | 0006260 | biological_process | DNA replication |
| A | 0006272 | biological_process | leading strand elongation |
| A | 0006275 | biological_process | regulation of DNA replication |
| A | 0030337 | molecular_function | DNA polymerase processivity factor activity |
| B | 0003677 | molecular_function | DNA binding |
| B | 0006260 | biological_process | DNA replication |
| B | 0006272 | biological_process | leading strand elongation |
| B | 0006275 | biological_process | regulation of DNA replication |
| B | 0030337 | molecular_function | DNA polymerase processivity factor activity |
| C | 0003677 | molecular_function | DNA binding |
| C | 0006260 | biological_process | DNA replication |
| C | 0006272 | biological_process | leading strand elongation |
| C | 0006275 | biological_process | regulation of DNA replication |
| C | 0030337 | molecular_function | DNA polymerase processivity factor activity |
| D | 0003677 | molecular_function | DNA binding |
| D | 0006260 | biological_process | DNA replication |
| D | 0006272 | biological_process | leading strand elongation |
| D | 0006275 | biological_process | regulation of DNA replication |
| D | 0030337 | molecular_function | DNA polymerase processivity factor activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO B 601 |
| Chain | Residue |
| B | SER135 |
| B | SER136 |
| B | ASP137 |
| B | ASP212 |
| C | ARG83 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO C 602 |
| Chain | Residue |
| C | ARG112 |
| C | HOH632 |
| C | HOH634 |
| A | ASN110 |
| C | PHE69 |
| C | ASN70 |
| C | TYR73 |
| site_id | AC3 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE EDO C 603 |
| Chain | Residue |
| C | SER135 |
| C | GLY138 |
| C | VAL174 |
| C | GLU175 |
| C | PHE176 |
| C | THR180 |
| C | GLY182 |
| C | HOH662 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO A 604 |
| Chain | Residue |
| A | TYR73 |
| A | PHE109 |
| A | ASN110 |
| C | ASN110 |
| C | VAL111 |
| C | ARG112 |
| site_id | AC5 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO B 605 |
| Chain | Residue |
| B | SER211 |
| B | TYR213 |
| B | PHE227 |
| B | PHE228 |
| B | ASN229 |
| B | HOH712 |
| B | HOH728 |
| site_id | AC6 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE EDO C 606 |
| Chain | Residue |
| C | THR133 |
| C | SER211 |
| C | TYR213 |
| C | PHE227 |
| C | PHE228 |
| C | ASN229 |
| C | HOH670 |
| C | HOH715 |
| site_id | AC7 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE EDO C 607 |
| Chain | Residue |
| B | LYS84 |
| B | GLU85 |
| B | SER104 |
| C | LEU210 |
| C | SER211 |
| C | ASP212 |
| C | ASN229 |
| C | GLU231 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO D 608 |
| Chain | Residue |
| D | VAL26 |
| D | GLU35 |
| D | LEU36 |
| D | VAL37 |
| D | GLU118 |
| D | HOH666 |
| site_id | AC9 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE EDO A 609 |
| Chain | Residue |
| A | GLN225 |
| A | THR237 |
| site_id | BC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO D 610 |
| Chain | Residue |
| D | SER211 |
| D | TYR213 |
| D | LYS215 |
| D | PHE227 |
| D | ASN229 |
| site_id | BC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO C 611 |
| Chain | Residue |
| B | ARG9 |
| B | ARG83 |
| B | LYS84 |
| C | VAL10 |
| C | ASP13 |
| C | LYS209 |
| C | HOH630 |
| site_id | BC3 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE EDO B 612 |
| Chain | Residue |
| B | ILE102 |
| B | HOH751 |
| site_id | BC4 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE EDO B 613 |
| Chain | Residue |
| B | PHE109 |
| site_id | BC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO A 614 |
| Chain | Residue |
| A | ASN70 |
| A | GLN72 |
| A | TYR73 |
| A | LYS76 |
| site_id | BC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO C 615 |
| Chain | Residue |
| B | EDO617 |
| C | ARG9 |
| C | ARG83 |
| site_id | BC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO D 616 |
| Chain | Residue |
| D | VAL80 |
| D | ALA81 |
| D | LYS82 |
| D | ARG83 |
| D | GLU85 |
| site_id | BC8 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO B 617 |
| Chain | Residue |
| B | VAL10 |
| B | ASP13 |
| B | LYS209 |
| B | HOH648 |
| C | ARG83 |
| C | LYS84 |
| C | EDO615 |
| site_id | BC9 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE EDO C 618 |
| Chain | Residue |
| C | ILE44 |
| C | TYR196 |
| C | SER197 |
| C | LEU240 |
| C | ALA241 |
| C | PRO242 |
| C | LYS243 |
| C | VAL244 |
| site_id | CC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO D 619 |
| Chain | Residue |
| D | PHE128 |
| D | SER131 |
| D | SER189 |
| site_id | CC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO C 620 |
| Chain | Residue |
| A | SER131 |
| A | GLU187 |
| A | LYS215 |
| C | LEU126 |
| C | GLN127 |
| C | PHE128 |
Functional Information from PROSITE/UniProt
| site_id | PS01251 |
| Number of Residues | 24 |
| Details | PCNA_1 Proliferating cell nuclear antigen signature 1. SVeLvALDrAHIsLIsVnLpremF |
| Chain | Residue | Details |
| A | SER33-PHE56 |
