2IHQ
Crystal Structure of the Rat Androgen Receptor Ligand Binding Domian Complex with an N-Aryl-Hydroxybicyclohydantoin
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE LG7 A 90 |
| Chain | Residue |
| A | LEU701 |
| A | MET749 |
| A | ARG752 |
| A | PHE764 |
| A | MET780 |
| A | MET787 |
| A | LEU873 |
| A | THR877 |
| A | MET895 |
| A | LEU704 |
| A | ASN705 |
| A | LEU707 |
| A | GLY708 |
| A | GLN711 |
| A | MET742 |
| A | MET745 |
| A | VAL746 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 3 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"11320241","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1I37","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Site: {"description":"Interaction with coactivator LXXL and FXXFY motifs","evidences":[{"source":"UniProtKB","id":"P10275","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Site: {"description":"Interaction with coactivator FXXLF and FXXFY motifs","evidences":[{"source":"UniProtKB","id":"P10275","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Phosphotyrosine; by CSK","evidences":[{"source":"UniProtKB","id":"P10275","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 3 |
| Details | Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)","evidences":[{"source":"UniProtKB","id":"P10275","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
