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2IF0

Crystal Structure of mouse Rab27b bound to GDP in monoclinic space group

Functional Information from GO Data
ChainGOidnamespacecontents
A0000166molecular_functionnucleotide binding
A0003924molecular_functionGTPase activity
A0003925molecular_functionG protein activity
A0005515molecular_functionprotein binding
A0005525molecular_functionGTP binding
A0005737cellular_componentcytoplasm
A0005768cellular_componentendosome
A0005770cellular_componentlate endosome
A0005794cellular_componentGolgi apparatus
A0005795cellular_componentGolgi stack
A0006887biological_processexocytosis
A0012505cellular_componentendomembrane system
A0016020cellular_componentmembrane
A0016324cellular_componentapical plasma membrane
A0016787molecular_functionhydrolase activity
A0017157biological_processregulation of exocytosis
A0019003molecular_functionGDP binding
A0019904molecular_functionprotein domain specific binding
A0030140cellular_componenttrans-Golgi network transport vesicle
A0030141cellular_componentsecretory granule
A0030672cellular_componentsynaptic vesicle membrane
A0031489molecular_functionmyosin V binding
A0032585cellular_componentmultivesicular body membrane
A0042470cellular_componentmelanosome
A0042589cellular_componentzymogen granule membrane
A0045921biological_processpositive regulation of exocytosis
A0048488biological_processsynaptic vesicle endocytosis
A0070382cellular_componentexocytic vesicle
A0071985biological_processmultivesicular body sorting pathway
A0099641biological_processanterograde axonal protein transport
A1904115cellular_componentaxon cytoplasm
B0000166molecular_functionnucleotide binding
B0003924molecular_functionGTPase activity
B0003925molecular_functionG protein activity
B0005515molecular_functionprotein binding
B0005525molecular_functionGTP binding
B0005737cellular_componentcytoplasm
B0005768cellular_componentendosome
B0005770cellular_componentlate endosome
B0005794cellular_componentGolgi apparatus
B0005795cellular_componentGolgi stack
B0006887biological_processexocytosis
B0012505cellular_componentendomembrane system
B0016020cellular_componentmembrane
B0016324cellular_componentapical plasma membrane
B0016787molecular_functionhydrolase activity
B0017157biological_processregulation of exocytosis
B0019003molecular_functionGDP binding
B0019904molecular_functionprotein domain specific binding
B0030140cellular_componenttrans-Golgi network transport vesicle
B0030141cellular_componentsecretory granule
B0030672cellular_componentsynaptic vesicle membrane
B0031489molecular_functionmyosin V binding
B0032585cellular_componentmultivesicular body membrane
B0042470cellular_componentmelanosome
B0042589cellular_componentzymogen granule membrane
B0045921biological_processpositive regulation of exocytosis
B0048488biological_processsynaptic vesicle endocytosis
B0070382cellular_componentexocytic vesicle
B0071985biological_processmultivesicular body sorting pathway
B0099641biological_processanterograde axonal protein transport
B1904115cellular_componentaxon cytoplasm
Functional Information from PDB Data
site_idAC1
Number of Residues2
DetailsBINDING SITE FOR RESIDUE MG A 602
ChainResidue
ATHR23
AGDP501

site_idAC2
Number of Residues2
DetailsBINDING SITE FOR RESIDUE MG B 502
ChainResidue
BTHR23
BGDP1501

site_idAC3
Number of Residues14
DetailsBINDING SITE FOR RESIDUE GDP A 501
ChainResidue
ATHR24
AASN133
ALYS134
AASP136
ALEU137
ASER163
AALA164
AALA165
AMG602
AGLY19
AVAL20
AGLY21
ALYS22
ATHR23

site_idAC4
Number of Residues18
DetailsBINDING SITE FOR RESIDUE GDP B 1501
ChainResidue
AASN35
APRO36
ALYS37
BASP17
BGLY19
BVAL20
BGLY21
BLYS22
BTHR23
BTHR24
BASN133
BLYS134
BASP136
BLEU137
BSER163
BALA164
BALA165
BMG502

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues8
DetailsBINDING: BINDING => ECO:0000269|PubMed:18940604
ChainResidueDetails
AASP17
ATHR75
ALYS134
AALA164
BASP17
BTHR75
BLYS134
BALA164

site_idSWS_FT_FI2
Number of Residues2
DetailsMOD_RES: N-acetylthreonine => ECO:0000250|UniProtKB:O00194
ChainResidueDetails
AASP3
BASP3

Catalytic Information from CSA
site_idCSA1
Number of Residues1
DetailsAnnotated By Reference To The Literature 1ksj
ChainResidueDetails
ALEU78

site_idCSA2
Number of Residues1
DetailsAnnotated By Reference To The Literature 1ksj
ChainResidueDetails
BLEU78

site_idCSA3
Number of Residues1
DetailsAnnotated By Reference To The Literature 1ksj
ChainResidueDetails
AGLY19

site_idCSA4
Number of Residues1
DetailsAnnotated By Reference To The Literature 1ksj
ChainResidueDetails
BGLY19

237423

PDB entries from 2025-06-11

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