2IDV

Crystal structure of wheat C113S mutant EIF4E bound TO 7-methyl-GDP

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003723	molecular_function	RNA binding
A	0003743	molecular_function	translation initiation factor activity
A	0005737	cellular_component	cytoplasm
A	0006413	biological_process	translational initiation

Functional Information from PDB Data

site_id	AC1
Number of Residues	12
Details	BINDING SITE FOR RESIDUE M7G A 1000

Chain	Residue
A	ARG58
A	HOH1076
A	HOH1092
A	HOH1093
A	TRP62
A	LYS107
A	TRP108
A	GLU109
A	ARG158
A	ARG163
A	HOH1012
A	HOH1066

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Functional Information from PROSITE/UniProt

site_id	PS00813
Number of Residues	24
Details	IF4E Eukaryotic initiation factor 4E signature. DFhcFKnkIePkWEDpisanGGKW

Chain	Residue	Details
A	ASP96-TRP119

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	BINDING: BINDING => ECO:0000269|PubMed:17322339, ECO:0007744|PDB:2IDV

Chain	Residue	Details
A	ARG58
A	LYS90
A	TRP108
A	ARG158

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site_id	SWS_FT_FI2
Number of Residues	1
Details	BINDING: BINDING => ECO:0000250|UniProtKB:Q00LS8

Chain	Residue	Details
A	LYS203

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